UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER052C

Length:

527

Number of sequences:

5887

Description:

YER052C HOM3 SGDID:S000000854, Chr V from 257958-256375, Genome Release 64-1-1, reverse complement, Verified ORF, "Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P10869	527	AK_YEAST Aspartokinase OS=Saccharomyces cerev...	527	0	1088	100	100	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0004072; F:aspartate kinase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006555; P:methionine metabolic process; TAS:SGD.::GO:0009088; P:threonine biosynthetic process; IMP:SGD.
2	O60163	519	AK_SCHPO Probable aspartokinase OS=Schizosacc...	495	0	548	56	72	GO:0005829; C:cytosol; IDA:PomBase.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; ISS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0006531; P:aspartate metabolic process; NAS:PomBase.::GO:0006555; P:methionine metabolic process; ISS:PomBase.::GO:0009088; P:threonine biosynthetic process; ISS:PomBase.
3	Q57991	473	AK_METJA Probable aspartokinase OS=JCM 10045 ...	506	9e-63	218	32	53
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0009089; P:lysine biosynthetic process via diaminopimelate; IEA:InterPro.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
4	Q9LYU8	569	AK1_ARATH Aspartokinase 1, chloroplastic OS=A...	497	7e-53	193	30	50	GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
5	O23653	544	AK2_ARATH Aspartokinase 2, chloroplastic OS=A...	506	1e-51	190	28	50	GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
6	Q9S702	559	AK3_ARATH Aspartokinase 3, chloroplastic OS=A...	501	2e-51	189	29	50	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IGI:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
7	O81852	916	AKH2_ARATH Bifunctional aspartokinase/homoser...	500	1e-44	173	26	48	GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IDA:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IDA:TAIR.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
8	P00561	820	AK1H_ECOLI Bifunctional aspartokinase/homoser...	531	1e-42	166	27	46
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IDA:EcoCyc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IDA:EcoCyc.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0009090; P:homoserine biosynthetic process; IDA:EcoCyc.::GO:0009089; P:lysine biosynthetic process via diaminopimelate; IDA:EcoCyc.::GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
9	Q9SA18	911	AKH1_ARATH Bifunctional aspartokinase/homoser...	503	2e-42	166	28	47	GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IDA:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IDA:TAIR.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
10	P27725	819	AK1H_SERMA Bifunctional aspartokinase/homoser...	91	0.34	37.4	21	55
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
11	P37142	921	AKH_DAUCA Bifunctional aspartokinase/homoseri...	500	3e-39	156	26	47	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
12	P49079	920	AKH1_MAIZE Bifunctional aspartokinase/homoser...	504	4e-39	156	26	45	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
13	P49080	917	AKH2_MAIZE Bifunctional aspartokinase/homoser...	502	1e-36	149	25	47
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
14	P44505	815	AKH_HAEIN Bifunctional aspartokinase/homoseri...	441	5e-36	146	30	49
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
15	Q8K9U9	814	AKH_BUCAP Bifunctional aspartokinase/homoseri...	506	3e-35	144	27	49
									GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
16	P57290	816	AKH_BUCAI Bifunctional aspartokinase/homoseri...	370	1e-34	142	29	51
									GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
17	P08660	449	AK3_ECOLI Lysine-sensitive aspartokinase 3 OS...	500	2e-33	135	27	47
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IDA:EcoCyc.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0009090; P:homoserine biosynthetic process; IDA:EcoCyc.::GO:0009089; P:lysine biosynthetic process via diaminopimelate; IDA:EcoCyc.
18	P94417	454	AK3_BACSU Probable aspartokinase OS=Bacillus ...	496	6e-27	116	24	44
									GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
19	Q89AR4	816	AKH_BUCBP Bifunctional aspartokinase/homoseri...	376	8e-26	115	26	47
									GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004412; F:homoserine dehydrogenase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
20	O69077	412	AK_PSEAE Aspartokinase OS=12228). GN=lysC Ord...	61	2.6	34.3	36	54
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
21	O67221	415	AK_AQUAE Aspartokinase OS=Aquifex aeolicus (s...	298	3e-21	99.8	29	50
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
22	P08495	408	AK2_BACSU Aspartokinase 2 OS=Bacillus subtili...	375	4e-20	96.3	26	49
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
23	Q59229	411	AK2_BACSG Aspartokinase 2 OS=Bacillus sp. (st...	369	1e-19	94.7	25	48
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
24	Q04795	404	AK1_BACSU Aspartokinase 1 OS=Bacillus subtili...	372	2e-19	94	26	46
									GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
25	Q9ZCI7	446	AK_RICPR Aspartokinase OS=Rickettsia prowazek...	505	2e-19	94.4	23	43
									GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004349; F:glutamate 5-kinase activity; IEA:InterPro.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.::GO:0006561; P:proline biosynthetic process; IEA:InterPro.
26	P53553	407	AK2_GEOSE Aspartokinase 2 OS=Geobacillus stea...	374	2e-19	94	27	48
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
27	Q92GF9	401	AK_RICCN Aspartokinase OS=Rickettsia conorii ...	481	2e-18	90.9	24	43
									GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004349; F:glutamate 5-kinase activity; IEA:InterPro.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.::GO:0006561; P:proline biosynthetic process; IEA:InterPro.
28	O25827	405	AK_HELPY Aspartokinase OS=pylori). GN=lysC Or...	496	3e-18	90.5	26	43
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
29	Q9PK32	437	AK_CHLMU Aspartokinase OS=Chlamydia muridarum...	309	3e-18	90.9	27	47
									GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
30	Q9ZJZ7	405	AK_HELPJ Aspartokinase OS=Helicobacter pylori...	487	4e-18	90.1	24	42
									GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
31	O84367	431	AK_CHLTR Aspartokinase OS=Chlamydia trachomat...	310	5e-17	87	27	48
									GO:0004072; F:aspartate kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.

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