rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
451 | P79735 | 215 | RAN_DANRE GTP-binding nuclear protein Ran OS=... | 197 | 9e-23 | 96.7 | 30 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 452 | P35290 | 203 | RAB24_MOUSE Ras-related protein Rab-24 OS=Mus... | 161 | 9e-23 | 96.3 | 32 | 57 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 453 | Q9YGC0 | 215 | RAN_SALSA GTP-binding nuclear protein Ran OS=... | 197 | 1e-22 | 96.3 | 30 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 454 | O17915 | 215 | RAN_CAEEL GTP-binding nuclear protein ran-1 O... | 196 | 2e-22 | 95.9 | 29 | 49 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0046785; P:microtubule polymerization; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 455 | P52301 | 216 | RAN_XENLA GTP-binding nuclear protein Ran OS=... | 196 | 2e-22 | 95.9 | 30 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 456 | Q7ZZX9 | 215 | RAN_CARAU GTP-binding nuclear protein Ran OS=... | 197 | 2e-22 | 95.5 | 29 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 457 | P42558 | 216 | RAN_CHICK GTP-binding nuclear protein Ran OS=... | 196 | 2e-22 | 95.5 | 30 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 458 | Q6GL85 | 216 | RAN_XENTR GTP-binding nuclear protein Ran OS=... | 196 | 2e-22 | 95.5 | 30 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 459 | P62828 | 216 | RAN_RAT GTP-binding nuclear protein Ran OS=Ra... | 196 | 2e-22 | 95.5 | 30 | 49 | GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 460 | Q5R556 | 216 | RAN_PONAB GTP-binding nuclear protein Ran OS=... | 196 | 2e-22 | 95.5 | 30 | 49 | GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 461 | P62827 | 216 | RAN_MOUSE GTP-binding nuclear protein Ran OS=... | 196 | 2e-22 | 95.5 | 30 | 49 | GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0034629; P:cellular protein complex localization; IMP:MGI.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006606; P:protein import into nucleus; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 462 | Q4R4M9 | 216 | RAN_MACFA GTP-binding nuclear protein Ran OS=... | 196 | 2e-22 | 95.5 | 30 | 49 | GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 463 | P62826 | 216 | RAN_HUMAN GTP-binding nuclear protein Ran OS=... | 196 | 2e-22 | 95.5 | 30 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; NAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003682; F:chromatin binding; TAS:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006259; P:DNA metabolic process; TAS:UniProtKB.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0007067; P:mitosis; TAS:UniProtKB.::GO:0007052; P:mitotic spindle organization; TAS:UniProtKB.::GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006611; P:protein export from nucleus; NAS:UniProtKB.::GO:0006405; P:RNA export from nucleus; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0046796; P:viral genome transport in host cell; TAS:Reactome.::GO:0019058; P:viral infectious cycle; TAS:Reactome. | 464 | P62825 | 216 | RAN_CANFA GTP-binding nuclear protein Ran OS=... | 196 | 2e-22 | 95.5 | 30 | 49 | GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 465 | Q3T054 | 216 | RAN_BOVIN GTP-binding nuclear protein Ran OS=... | 196 | 2e-22 | 95.5 | 30 | 49 | GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 466 | Q7ZYF1 | 273 | DJ27A_XENLA DnaJ homolog subfamily C member 2... | 195 | 3e-22 | 95.9 | 27 | 51 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 467 | P32836 | 220 | GSP2_YEAST GTP-binding nuclear protein GSP2/C... | 154 | 5e-22 | 94.7 | 32 | 55 | GO:0005634; C:nucleus; IGI:SGD. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IGI:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0006997; P:nucleus organization; IGI:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 468 | P32835 | 219 | GSP1_YEAST GTP-binding nuclear protein GSP1/C... | 154 | 5e-22 | 94.7 | 32 | 55 | GO:0005737; C:cytoplasm; TAS:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IGI:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; TAS:SGD.::GO:0006997; P:nucleus organization; IGI:SGD.::GO:0031938; P:regulation of chromatin silencing at telomere; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 469 | Q54FK7 | 204 | RABL_DICDI Ras-related protein RabL OS=Dictyo... | 163 | 7e-22 | 94 | 29 | 53 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 470 | P23175 | 189 | RASH_MSVNS GTPase HRas OS=Murine sarcoma viru... | 164 | 9e-22 | 93.2 | 34 | 55 | GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 471 | Q6IMM1 | 273 | DJC27_CHICK DnaJ homolog subfamily C member 2... | 168 | 1e-21 | 94.4 | 26 | 54 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 472 | P70426 | 219 | RIT1_MOUSE GTP-binding protein Rit1 OS=Mus mu... | 165 | 1e-21 | 93.2 | 35 | 49 | GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:MGI.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 473 | P32254 | 194 | RASS_DICDI Ras-like protein rasS OS=Dictyoste... | 162 | 2e-21 | 92.8 | 36 | 53 | GO:0005622; C:intracellular; IC:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:dictyBase.::GO:0003924; F:GTPase activity; ISS:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:dictyBase.::GO:0000902; P:cell morphogenesis; IMP:dictyBase.::GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:dictyBase.::GO:0051271; P:negative regulation of cellular component movement; IMP:dictyBase.::GO:0050766; P:positive regulation of phagocytosis; IMP:dictyBase.::GO:0007265; P:Ras protein signal transduction; ISS:dictyBase.::GO:0042127; P:regulation of cell proliferation; IMP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase. | 474 | Q6FR65 | 214 | GSP1_CANGA GTP-binding nuclear protein GSP1/R... | 154 | 2e-21 | 93.2 | 32 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 475 | Q92963 | 219 | RIT1_HUMAN GTP-binding protein Rit1 OS=Homo s... | 165 | 2e-21 | 93.2 | 35 | 48 | GO:0005886; C:plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005516; F:calmodulin binding; TAS:ProtInc.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 476 | P32253 | 189 | RASC_DICDI Ras-like protein rasC OS=Dictyoste... | 164 | 2e-21 | 92.4 | 37 | 52 | GO:0005622; C:intracellular; IC:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031982; C:vesicle; IDA:dictyBase. | | | | | | | | | | GO:0005525; F:GTP binding; IDA:dictyBase.::GO:0003924; F:GTPase activity; IDA:dictyBase. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:dictyBase.::GO:0007190; P:activation of adenylate cyclase activity; IGI:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0008283; P:cell proliferation; IGI:dictyBase.::GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:dictyBase.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IMP:dictyBase.::GO:0031276; P:negative regulation of lateral pseudopodium assembly; IMP:dictyBase.::GO:0030828; P:positive regulation of cGMP biosynthetic process; IMP:dictyBase.::GO:0051491; P:positive regulation of filopodium assembly; IMP:dictyBase.::GO:0031284; P:positive regulation of guanylate cyclase activity; IMP:dictyBase.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:dictyBase.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:dictyBase.::GO:0043491; P:protein kinase B signaling cascade; IMP:dictyBase.::GO:0007265; P:Ras protein signal transduction; IDA:dictyBase.::GO:0001558; P:regulation of cell growth; IMP:dictyBase. | 477 | Q7F7I7 | 221 | RAN1_ORYSJ GTP-binding nuclear protein Ran-1 ... | 194 | 2e-21 | 92.8 | 30 | 49 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 478 | A2WSI7 | 221 | RAN1_ORYSI GTP-binding nuclear protein Ran-1 ... | 194 | 2e-21 | 92.8 | 30 | 49 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 479 | Q94694 | 188 | RAP1_PHYPO Ras-related protein Rap-1 OS=Physa... | 166 | 3e-21 | 92 | 35 | 54 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 480 | P01113 | 189 | RASH_MSVMO GTPase HRas OS=Moloney murine sarc... | 164 | 3e-21 | 91.7 | 34 | 55 | GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 481 | Q7GD79 | 221 | RAN2_ORYSJ GTP-binding nuclear protein Ran-2 ... | 157 | 3e-21 | 92.4 | 32 | 54 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |