Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER023W
Length:
286
Number of sequences:
5887
Description:
YER023W PRO3 SGDID:S000000825, Chr V from 201076-201936, Genome Release 64-1-1, Verified ORF, "Delta 1-pyrroline-5-carboxylate reductase, catalyzes the last step in proline biosynthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32263    286   P5CR_YEAST Pyrroline-5-carboxylate reductase ...2860     578     100     100GO:0005737; C:cytoplasm; IDA:SGD.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IGI:SGD.
GO:0006561; P:proline biosynthetic process; IMP:SGD.
2Q12740    320   P5CR_ZALAR Pyrroline-5-carboxylate reductase ...3064e-49     171     37     54
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
3Q9P7Y7    282   P5CR_SCHPO Pyrroline-5-carboxylate reductase ...2866e-46     162     34     57GO:0005829; C:cytosol; IDA:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; ISS:PomBase.
GO:0006561; P:proline biosynthetic process; ISS:PomBase.
4P74572    267   P5CR_SYNY3 Pyrroline-5-carboxylate reductase ...2865e-40     145     33     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
5P0C1E4    270   P5CR_CORGL Pyrroline-5-carboxylate reductase ...2882e-39     144     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
6P0C1E5    270   P5CR_CORML Pyrroline-5-carboxylate reductase ...2876e-39     143     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
7P54904    276   P5CR1_ARATH Pyrroline-5-carboxylate reductase...2855e-38     140     31     54GO:0005618; C:cell wall; IDA:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IGI:TAIR.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.::GO:0009408; P:response to heat; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
8Q04708    273   P5CR_PEA Pyrroline-5-carboxylate reductase OS...2838e-37     137     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
9P17817    274   P5CR_SOYBN Pyrroline-5-carboxylate reductase ...2837e-36     135     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
10O04016    278   P5CR_ACTCH Pyrroline-5-carboxylate reductase ...2862e-34     131     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
11Q922W5    309   P5CR1_MOUSE Pyrroline-5-carboxylate reductase...2051e-30     121     36     52GO:0005739; C:mitochondrion; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; ISS:UniProtKB.
GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.::GO:0006561; P:proline biosynthetic process; ISS:UniProtKB.
12Q8CP51    271   P5CR_STAES Pyrroline-5-carboxylate reductase ...2665e-30     119     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
13Q5HP48    271   P5CR_STAEQ Pyrroline-5-carboxylate reductase ...2665e-30     119     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
14Q53H96    274   P5CR3_HUMAN Pyrroline-5-carboxylate reductase...2132e-29     117     35     54
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
15A1L2Q8    274   P5CR3_XENLA Pyrroline-5-carboxylate reductase...2172e-29     117     35     53
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
16Q58DT4    320   P5CR1_BOVIN Pyrroline-5-carboxylate reductase...2052e-29     118     35     52GO:0005739; C:mitochondrion; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; ISS:UniProtKB.
GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.::GO:0006561; P:proline biosynthetic process; ISS:UniProtKB.
17P54552    278   P5CR2_BACSU Pyrroline-5-carboxylate reductase...2833e-29     117     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
18Q5R9X6    319   P5CR1_PONAB Pyrroline-5-carboxylate reductase...2057e-29     117     35     52GO:0005739; C:mitochondrion; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; ISS:UniProtKB.
GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.::GO:0006561; P:proline biosynthetic process; ISS:UniProtKB.
19P32322    319   P5CR1_HUMAN Pyrroline-5-carboxylate reductase...2057e-29     117     35     52GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IDA:UniProtKB.
GO:0034599; P:cellular response to oxidative stress; IMP:UniProtKB.::GO:0006561; P:proline biosynthetic process; IDA:UniProtKB.
20Q5RAQ3    320   P5CR2_PONAB Pyrroline-5-carboxylate reductase...2041e-28     116     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
21Q9HH99    270   P5CR_METAC Pyrroline-5-carboxylate reductase ...2851e-28     115     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
22Q96C36    320   P5CR2_HUMAN Pyrroline-5-carboxylate reductase...2046e-28     114     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
23Q4R6W7    320   P5CR2_MACFA Pyrroline-5-carboxylate reductase...2046e-28     114     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
24Q17QJ7    320   P5CR2_BOVIN Pyrroline-5-carboxylate reductase...2046e-28     114     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
25Q922Q4    320   P5CR2_MOUSE Pyrroline-5-carboxylate reductase...2041e-27     113     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
26Q6AY23    320   P5CR2_RAT Pyrroline-5-carboxylate reductase 2...2041e-27     113     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
27Q58D08    308   P5CR3_BOVIN Pyrroline-5-carboxylate reductase...2822e-27     112     30     46
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
28Q4R531    274   P5CR3_MACFA Pyrroline-5-carboxylate reductase...2872e-27     112     30     45
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
29P0A9L9    269   P5CR_SHIFL Pyrroline-5-carboxylate reductase ...2723e-27     111     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
30P0A9L8    269   P5CR_ECOLI Pyrroline-5-carboxylate reductase ...2723e-27     111     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050661; F:NADP binding; IDA:EcoCyc.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IDA:EcoCyc.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
31Q4L6K3    271   P5CR_STAHJ Pyrroline-5-carboxylate reductase ...2654e-27     111     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
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