UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER022W

Length:

687

Number of sequences:

5887

Description:

YER022W SRB4 SGDID:S000000824, Chr V from 198812-200875, Genome Release 64-1-1, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; homozygosity of the human MED17 L371P mutation is associated with infantile cerebral and cerebellar atrophy with poor myelination"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P32569	687	MED17_YEAST Mediator of RNA polymerase II tra...	687	0	1382	100	100	GO:0070847; C:core mediator complex; IDA:SGD.::GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0033613; F:activating transcription factor binding; IDA:SGD.::GO:0001139; F:core RNA polymerase II recruiting transcription factor activity; IMP:SGD.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.::GO:0005198; F:structural molecule activity; IMP:SGD.
									GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.
2	Q6FQ87	676	MED17_CANGA Mediator of RNA polymerase II tra...	702	0	590	47	67	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
3	Q75D58	639	MED17_ASHGO Mediator of RNA polymerase II tra...	683	6e-159	480	42	63	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
4	Q6CR96	671	MED17_KLULA Mediator of RNA polymerase II tra...	693	3e-148	453	41	61	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
5	Q5AHZ7	565	MED17_CANAL Mediator of RNA polymerase II tra...	461	1e-46	178	31	52	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
6	A3LRF0	587	MED17_PICST Mediator of RNA polymerase II tra...	617	3e-44	171	28	48	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
7	Q6C022	511	MED17_YARLI Mediator of RNA polymerase II tra...	374	9e-31	130	29	48	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
8	A1CV59	639	MED17_NEOFI Mediator of RNA polymerase II tra...	422	3e-24	111	25	50	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
9	Q5B8A6	632	MED17_EMENI Mediator of RNA polymerase II tra...	428	2e-23	108	25	47	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
10	Q4W9B7	639	MED17_ASPFU Mediator of RNA polymerase II tra...	422	2e-23	108	25	50	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
11	Q0CG59	634	MED17_ASPTN Mediator of RNA polymerase II tra...	389	4e-20	98.6	23	47	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
12	Q2UJ16	638	MED17_ASPOR Mediator of RNA polymerase II tra...	395	7e-20	97.8	25	47	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
13	A1CLT5	641	MED17_ASPCL Mediator of RNA polymerase II tra...	280	3e-18	92.4	28	52	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
14	Q1DLD2	691	MED17_COCIM Mediator of RNA polymerase II tra...	357	5e-18	92	26	47	GO:0016592; C:mediator complex; IEA:InterPro.
									GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
15	P87306	545	MED17_SCHPO Mediator of RNA polymerase II tra...	243	0.000000000001	74.3	30	50	GO:0016592; C:mediator complex; IDA:PomBase.
									GO:0005515; F:protein binding; IPI:PomBase.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.

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