Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER021W
Length:
523
Number of sequences:
5887
Description:
YER021W RPN3 SGDID:S000000823, Chr V from 196948-198519, Genome Release 64-1-1, Verified ORF, "Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40016    523   RPN3_YEAST 26S proteasome regulatory subunit ...5230     1071     100     100GO:0008541; C:proteasome regulatory particle, lid subcomplex; IDA:SGD.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:SGD.
2O42897    497   RPN3_SCHPO Probable 26S proteasome regulatory...4775e-103     325     39     61GO:0005634; C:nucleus; TAS:PomBase.::GO:0008541; C:proteasome regulatory particle, lid subcomplex; ISS:PomBase.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; NAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
3Q9U5Z8    500   PSMD3_ANOST Probable 26S proteasome non-ATPas...4772e-81     268     35     58GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
4O61470    496   PSMD3_ANOGA Probable 26S proteasome non-ATPas...4806e-81     267     34     57GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
5P25161    494   PSMD3_DROME Probable 26S proteasome non-ATPas...4852e-75     253     33     56GO:0008541; C:proteasome regulatory particle, lid subcomplex; ISS:FlyBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0004175; F:endopeptidase activity; IDA:FlyBase.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0006508; P:proteolysis; IDA:FlyBase.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
6O43242    534   PSMD3_HUMAN 26S proteasome non-ATPase regulat...4453e-74     251     34     59GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; TAS:ProtInc.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
7Q2KJ46    534   PSMD3_BOVIN 26S proteasome non-ATPase regulat...4454e-74     250     34     60GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
8P14685    530   PSMD3_MOUSE 26S proteasome non-ATPase regulat...4455e-74     250     34     60GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
9Q1ZXD3    504   PSMD3_DICDI 26S proteasome non-ATPase regulat...4641e-70     240     33     56GO:0005813; C:centrosome; IDA:dictyBase.::GO:0000502; C:proteasome complex; ISS:dictyBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0004175; F:endopeptidase activity; ISS:dictyBase.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase.
10Q9LNU4    488   PSD31_ARATH Probable 26S proteasome non-ATPas...4915e-64     222     33     54GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
11Q9LQR8    487   PSD32_ARATH Probable 26S proteasome non-ATPas...4672e-63     220     35     54GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; TAS:TAIR.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
12Q06364    489   PSMD3_DAUCA Probable 26S proteasome non-ATPas...3581e-62     218     38     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
13P93768    488   PSMD3_TOBAC Probable 26S proteasome non-ATPas...3667e-61     214     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
14Q04908    504   PSMD3_CAEEL 26S proteasome non-ATPase regulat...3201e-55     200     36     60GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0000003; P:reproduction; IMP:WormBase.
15Q8SRT7    376   RPN3_ENCCU 26S proteasome regulatory subunit ...2210.00000000000007     76.6     32     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
16A6H7B5    423   CSN3_BOVIN COP9 signalosome complex subunit 3...1260.00002     50.4     25     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
17O88543    423   CSN3_MOUSE COP9 signalosome complex subunit 3...1260.0004     46.6     23     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.
GO:0001701; P:in utero embryonic development; IMP:MGI.
18Q68FW9    423   CSN3_RAT COP9 signalosome complex subunit 3 O...1260.0006     45.8     23     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
19Q5RFS2    423   CSN3_PONAB COP9 signalosome complex subunit 3...1260.0006     45.8     23     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
20Q4R898    423   CSN3_MACFA COP9 signalosome complex subunit 3...1260.0006     45.8     23     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
21Q9UNS2    423   CSN3_HUMAN COP9 signalosome complex subunit 3...1260.0006     45.8     23     48GO:0005737; C:cytoplasm; IDA:HPA.::GO:0008180; C:signalosome; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0010388; P:cullin deneddylation; IDA:UniProtKB.::GO:0009416; P:response to light stimulus; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
22Q5ZJF1    423   CSN3_CHICK COP9 signalosome complex subunit 3...1260.001     45.1     23     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
23Q7ZTN8    423   CSN3_XENLA COP9 signalosome complex subunit 3...1260.002     44.3     23     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
24Q6P2U9    423   CSN3_DANRE COP9 signalosome complex subunit 3...1260.002     44.3     23     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
25Q28IV6    423   CSN3_XENTR COP9 signalosome complex subunit 3...1260.002     44.3     23     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
26Q8SYG2    445   CSN3_DROME COP9 signalosome complex subunit 3...800.023     40.8     28     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IMP:UniProtKB.
GO:0019781; F:NEDD8 activating enzyme activity; IMP:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0000338; P:protein deneddylation; IMP:UniProtKB.::GO:0050821; P:protein stabilization; IMP:FlyBase.
27Q8W575    429   CSN3_ARATH COP9 signalosome complex subunit 3...1230.04     40     25     44GO:0005829; C:cytosol; IDA:TAIR.::GO:0008180; C:signalosome; IPI:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0010388; P:cullin deneddylation; IMP:TAIR.::GO:0000085; P:G2 phase of mitotic cell cycle; IMP:TAIR.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
28Q4P8T5    454   CSN12_USTMA Protein CSN12 homolog OS=Ustilago...1420.068     39.3     25     43
29Q54E53    418   CSN3_DICDI COP9 signalosome complex subunit 3...1090.093     38.9     23     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008180; C:signalosome; IPI:dictyBase.
GO:0005515; F:protein binding; IPI:dictyBase.
30A7F3L0    451   EIF3E_SCLS1 Eukaryotic translation initiation...2520.43     37     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
31Q8NS93    985   Y786_CORGL UPF0182 protein Cgl0786/cg0896 OS=...580.81     36.2     33     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
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