UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER018C

Length:

221

Number of sequences:

5887

Description:

YER018C SPC25 SGDID:S000000820, Chr V from 192624-191959, Genome Release 64-1-1, reverse complement, Verified ORF, "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	P48679	665	LMNA_RAT Prelamin-A/C OS=Rattus norvegicus (R...	68	5.8	31.6	29	56	GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005635; C:nuclear envelope; ISS:UniProtKB.::GO:0016363; C:nuclear matrix; IDA:RGD.
									GO:0005198; F:structural molecule activity; TAS:RGD.
									GO:0006998; P:nuclear envelope organization; TAS:RGD.::GO:0090343; P:positive regulation of cell aging; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEP:RGD.
32	Q7UM33	881	CLPB_RHOBA Chaperone protein ClpB OS=Rhodopir...	64	5.9	31.6	25	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
									GO:0016485; P:protein processing; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
33	O42649	1194	SMC3_SCHPO Structural maintenance of chromoso...	104	6.1	31.6	22	48	GO:0000794; C:condensed nuclear chromosome; IC:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0030892; C:mitotic cohesin complex; TAS:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:PomBase.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007064; P:mitotic sister chromatid cohesion; IMP:UniProtKB.::GO:0016567; P:protein ubiquitination; ISS:PomBase.
34	P02468	1607	LAMC1_MOUSE Laminin subunit gamma-1 OS=Mus mu...	88	6.2	31.6	24	43	GO:0005604; C:basement membrane; ISS:HGNC.
									GO:0005201; F:extracellular matrix structural constituent; ISS:HGNC.
									GO:0007155; P:cell adhesion; ISS:HGNC.::GO:0016477; P:cell migration; ISS:HGNC.::GO:0022617; P:extracellular matrix disassembly; ISS:HGNC.::GO:0031581; P:hemidesmosome assembly; ISS:HGNC.::GO:0006461; P:protein complex assembly; ISS:HGNC.
35	Q9LBG3	1653	PAA_STRCG Probable cell-surface antigen I/II ...	101	6.6	31.6	26	50	GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0009274; C:peptidoglycan-based cell wall; IEA:InterPro.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0044406; P:adhesion to host; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:InterPro.
36	P50532	1290	SMC4_XENLA Structural maintenance of chromoso...	100	6.7	31.6	22	48	GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007076; P:mitotic chromosome condensation; ISS:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
37	Q5ZJY5	1065	SMC5_CHICK Structural maintenance of chromoso...	73	7.5	31.2	30	47	GO:0000781; C:chromosome, telomeric region; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090398; P:cellular senescence; ISS:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.::GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.::GO:0000722; P:telomere maintenance via recombination; ISS:UniProtKB.
38	A0JNT9	577	BICR1_MOUSE Bicaudal D-related protein 1 OS=M...	69	7.7	31.2	32	55	GO:0005813; C:centrosome; IDA:UniProtKB.
									GO:0034452; F:dynactin binding; IDA:UniProtKB.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
									GO:0055107; P:Golgi to secretory granule transport; IMP:UniProtKB.::GO:0031175; P:neuron projection development; IMP:UniProtKB.
39	Q6ZRK6	1079	CCD73_HUMAN Coiled-coil domain-containing pro...	97	9.5	31.2	23	47
40	P32380	944	SP110_YEAST Spindle pole body component 110 O...	99	9.5	31.2	24	46	GO:0005823; C:central plaque of spindle pole body; IDA:SGD.::GO:0005822; C:inner plaque of spindle pole body; IDA:SGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0005200; F:structural constituent of cytoskeleton; IPI:SGD.
									GO:0000742; P:karyogamy involved in conjugation with cellular fusion; IMP:SGD.::GO:0007020; P:microtubule nucleation; IPI:SGD.
41	Q9Y496	699	KIF3A_HUMAN Kinesin-like protein KIF3A OS=Hom...	116	10	30.8	23	44	GO:0005813; C:centrosome; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016939; C:kinesin II complex; IDA:BHF-UCL.::GO:0072372; C:primary cilium; ISS:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:BHF-UCL.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008574; F:plus-end-directed microtubule motor activity; TAS:BHF-UCL.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0006996; P:organelle organization; TAS:ProtInc.::GO:0072383; P:plus-end-directed vesicle transport along microtubule; TAS:BHF-UCL.

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