Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER017C
Length:
761
Number of sequences:
5887
Description:
YER017C AFG3 SGDID:S000000819, Chr V from 191788-189503, Genome Release 64-1-1, reverse complement, Verified ORF, "Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451Q6NW58    570   SPAST_DANRE Spastin OS=Danio rerio (Zebrafish...2961e-30     131     34     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; ISS:UniProtKB.
GO:0048676; P:axon extension involved in development; IMP:ZFIN.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:ZFIN.::GO:0031122; P:cytoplasmic microtubule organization; IMP:ZFIN.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0051013; P:microtubule severing; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:ZFIN.::GO:0045773; P:positive regulation of axon extension; IMP:ZFIN.::GO:0031117; P:positive regulation of microtubule depolymerization; IMP:ZFIN.::GO:0034214; P:protein hexamerization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
452B2RYN7    581   SPAST_RAT Spastin OS=Rattus norvegicus (Rat)....2411e-30     131     36     54GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007109; P:cytokinesis, completion of separation; ISS:UniProtKB.::GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0051013; P:microtubule severing; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0034214; P:protein hexamerization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
453Q9QYY8    614   SPAST_MOUSE Spastin OS=Mus musculus (Mouse). ...2411e-30     131     36     54GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007109; P:cytokinesis, completion of separation; ISS:UniProtKB.::GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0051013; P:microtubule severing; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0034214; P:protein hexamerization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
454B3P8A3    758   SPAST_DROER Spastin OS=Drosophila erecta (Fru...2751e-30     132     36     51GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051013; P:microtubule severing; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
455B4PL32    758   SPAST_DROYA Spastin OS=Drosophila yakuba (Fru...2752e-30     132     36     51GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051013; P:microtubule severing; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
456B4QSF0    758   SPAST_DROSI Spastin OS=Drosophila simulans (F...2752e-30     131     36     51GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051013; P:microtubule severing; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
457P52917    437   VPS4_YEAST Vacuolar protein sorting-associate...2412e-30     128     38     54GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0042803; F:protein homodimerization activity; IDA:SGD.
GO:0070676; P:intralumenal vesicle formation; IMP:SGD.::GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IMP:SGD.::GO:0051260; P:protein homooligomerization; IDA:SGD.::GO:0045053; P:protein retention in Golgi apparatus; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016125; P:sterol metabolic process; IMP:SGD.
458Q6PIW4    674   FIGL1_HUMAN Fidgetin-like protein 1 OS=Homo s...2335e-30     130     34     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0046034; P:ATP metabolic process; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.::GO:0033687; P:osteoblast proliferation; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.
459Q60QD1    591   FIGL1_CAEBR Fidgetin-like protein 1 OS=Caenor...2345e-30     129     36     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0046034; P:ATP metabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
460Q5U3S1    488   KATL1_DANRE Katanin p60 ATPase-containing sub...2781e-29     127     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
461A8QFF6    454   SPAST_BRUMA Probable spastin homolog Bm1_5336...2512e-29     126     36     56GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0034214; P:protein hexamerization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
462Q4JVP5    517   ARC_CORJK AAA ATPase forming ring-shaped comp...1982e-29     126     36     58GO:0000502; C:proteasome complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
463C3PGA0    524   ARC_CORA7 AAA ATPase forming ring-shaped comp...2603e-29     126     32     50GO:0000502; C:proteasome complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
464P46461    745   NSF1_DROME Vesicle-fusing ATPase 1 OS=Drosoph...2513e-29     128     35     54GO:0005737; C:cytoplasm; NAS:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:FlyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007030; P:Golgi organization; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IDA:FlyBase.::GO:0016082; P:synaptic vesicle priming; NAS:FlyBase.
465C4LIL2    572   ARC_CORK4 AAA ATPase forming ring-shaped comp...2293e-29     127     34     55GO:0000502; C:proteasome complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
466O27092    372   PRS2_METTH Putative 26S protease regulatory s...2575e-29     124     33     51GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
467P40328    754   TBP6_YEAST Probable 26S protease subunit YTA6...2496e-29     127     35     53GO:0005938; C:cell cortex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
468Q0VD48    444   VPS4B_BOVIN Vacuolar protein sorting-associat...2411e-28     123     37     55GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
469B1VDV2    538   ARC_CORU7 AAA ATPase forming ring-shaped comp...2082e-28     124     35     53GO:0000502; C:proteasome complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
470P46467    444   VPS4B_MOUSE Vacuolar protein sorting-associat...2412e-28     122     37     54GO:0005829; C:cytosol; IDA:MGI.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007032; P:endosome organization; IMP:MGI.::GO:0006813; P:potassium ion transport; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
471P46459    744   NSF_HUMAN Vesicle-fusing ATPase OS=Homo sapie...680.23     38.5     29     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.
GO:0006887; P:exocytosis; TAS:UniProtKB.::GO:0045026; P:plasma membrane fusion; TAS:UniProtKB.::GO:0001921; P:positive regulation of receptor recycling; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome.
472P18708    744   NSF_CRIGR Vesicle-fusing ATPase OS=Cricetulus...680.23     38.5     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
473P46460    744   NSF_MOUSE Vesicle-fusing ATPase OS=Mus muscul...680.23     38.5     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; IMP:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019905; F:syntaxin binding; IDA:MGI.
GO:0006813; P:potassium ion transport; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
474Q5R410    744   NSF_PONAB Vesicle-fusing ATPase OS=Pongo abel...680.23     38.5     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
475Q9QUL6    744   NSF_RAT Vesicle-fusing ATPase OS=Rattus norve...680.22     38.5     29     51GO:0043198; C:dendritic shaft; IDA:UniProtKB.::GO:0005795; C:Golgi stack; IDA:RGD.::GO:0014069; C:postsynaptic density; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0017137; F:Rab GTPase binding; IDA:RGD.
GO:0007269; P:neurotransmitter secretion; TAS:UniProtKB.::GO:0015031; P:protein transport; IMP:RGD.::GO:0017157; P:regulation of exocytosis; IMP:RGD.::GO:0006906; P:vesicle fusion; TAS:UniProtKB.
476Q54KQ7    655   SPAST_DICDI Spastin OS=Dictyostelium discoide...2365e-28     123     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
477O75351    444   VPS4B_HUMAN Vacuolar protein sorting-associat...2416e-28     121     37     54GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005774; C:vacuolar membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IMP:UniProtKB.::GO:0042623; F:ATPase activity, coupled; NAS:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0032510; P:endosome to lysosome transport via multivesicular body sorting pathway; IMP:UniProtKB.::GO:0032367; P:intracellular cholesterol transport; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0033993; P:response to lipid; IDA:UniProtKB.
478Q9SEX2    523   KTNA1_ARATH Katanin p60 ATPase-containing sub...2977e-28     122     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0043622; P:cortical microtubule organization; IMP:TAIR.::GO:0009825; P:multidimensional cell growth; IMP:TAIR.::GO:0009832; P:plant-type cell wall biogenesis; IMP:TAIR.::GO:0010091; P:trichome branching; IMP:TAIR.
479Q503W7    362   ATD1B_DANRE ATPase family AAA domain-containi...2867e-28     120     31     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:EC.
480Q9UN37    437   VPS4A_HUMAN Vacuolar protein sorting-associat...2297e-28     121     40     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; NAS:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0000910; P:cytokinesis; IDA:UniProtKB.::GO:0016197; P:endosome transport; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
481C5CBU4    584   ARC_MICLC AAA ATPase forming ring-shaped comp...2047e-28     122     37     56GO:0000502; C:proteasome complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
GO:0019941; P:modification-dependent protein catabolic process; IEA:InterPro.::GO:0010498; P:proteasomal protein catabolic process; IEA:InterPro.
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