Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER007W
Length:
518
Number of sequences:
5887
Description:
YER007W PAC2 SGDID:S000000809, Chr V from 164527-166083, Genome Release 64-1-1, Verified ORF, "Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31B2LT65    784   TLR2_SHEEP Toll-like receptor 2 OS=Ovis aries...1382     35     33     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
32B2LT64    784   TLR2_GIRCA Toll-like receptor 2 OS=Giraffa ca...1389.7     32.7     32     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
33O43300    516   LRRT2_HUMAN Leucine-rich repeat transmembrane...1650.003     43.9     33     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
34Q0GC71    784   TLR2_CAPHI Toll-like receptor 2 OS=Capra hirc...1380.41     37     34     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
35Q8YA32    1778   INLI_LISMO Internalin-I OS=Listeria monocytog...1697.2     33.1     26     46GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
36Q8BGA3    515   LRRT2_MOUSE Leucine-rich repeat transmembrane...1650.003     43.5     33     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
37D4A7P2    515   LRRT2_RAT Leucine-rich repeat transmembrane n...1650.004     43.5     33     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0042043; F:neurexin family protein binding; IPI:BHF-UCL.
38B2LT62    784   TLR2_CAPIB Toll-like receptor 2 OS=Capra ibex...1382.1     35     33     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
39Q9C000    1473   NALP1_HUMAN NACHT, LRR and PYD domains-contai...1520.004     43.9     28     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0072558; C:NLRP1 inflammasome complex; TAS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IDA:HGNC.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
GO:0042742; P:defense response to bacterium; ISS:BHF-UCL.::GO:0006917; P:induction of apoptosis; NAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0051402; P:neuron apoptotic process; IDA:HGNC.::GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.::GO:0050718; P:positive regulation of interleukin-1 beta secretion; ISS:BHF-UCL.::GO:0050727; P:regulation of inflammatory response; IC:BHF-UCL.::GO:0032495; P:response to muramyl dipeptide; ISS:BHF-UCL.
40O60346    1717   PHLP1_HUMAN PH domain leucine-rich repeat-con...1609.5     32.7     29     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; TAS:Reactome.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
41P49606    2493   CYAA_USTMA Adenylate cyclase OS=Ustilago mayd...1340.004     43.9     29     49
GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
42Q05443    342   LUM_BOVIN Lumican OS=Bos taurus (Bovine). GN=...1444     33.5     28     47
43Q9WTR8    1696   PHLP1_RAT PH domain leucine-rich repeat prote...2470.005     43.5     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:RGD.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0006470; P:protein dephosphorylation; IDA:RGD.
44Q7SXW3    601   LRC40_DANRE Leucine-rich repeat-containing pr...2230.005     43.1     27     41
45Q86WI3    1866   NLRC5_HUMAN Protein NLRC5 OS=Homo sapiens (Hu...1390.046     40.4     30     50GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:BHF-UCL.
GO:0051607; P:defense response to virus; IEP:UniProtKB.::GO:0045087; P:innate immune response; IMP:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0060339; P:negative regulation of type I interferon-mediated signaling pathway; IDA:UniProtKB.::GO:0060335; P:positive regulation of interferon-gamma-mediated signaling pathway; IDA:UniProtKB.::GO:0045345; P:positive regulation of MHC class I biosynthetic process; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IDA:UniProtKB.::GO:0043549; P:regulation of kinase activity; IDA:UniProtKB.
46Q6XHA6    2646   ROC10_DICDI Probable inactive serine/threonin...1660.006     43.1     28     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
47P58682    1032   TLR8_MOUSE Toll-like receptor 8 OS=Mus muscul...1580.006     43.1     34     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.
GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0045089; P:positive regulation of innate immune response; ISS:UniProtKB.::GO:0045356; P:positive regulation of interferon-alpha biosynthetic process; ISS:UniProtKB.::GO:0045359; P:positive regulation of interferon-beta biosynthetic process; ISS:UniProtKB.::GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; ISS:UniProtKB.::GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; ISS:UniProtKB.
48Q9ZPS9    1143   BRL2_ARATH Serine/threonine-protein kinase BR...1930.006     43.1     32     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0009734; P:auxin mediated signaling pathway; IMP:TAIR.::GO:0009742; P:brassinosteroid mediated signaling pathway; IMP:TAIR.::GO:0010305; P:leaf vascular tissue pattern formation; IMP:TAIR.::GO:0010233; P:phloem transport; IDA:TAIR.
49O46379    192   LUM_RABIT Lumican OS=Oryctolagus cuniculus (R...950.29     36.6     31     52
50Q7KRY7    1851   LAP4_DROME Protein lap4 OS=Drosophila melanog...1920.42     37.4     29     44GO:0016323; C:basolateral plasma membrane; IDA:FlyBase.::GO:0005576; C:extracellular region; IDA:UniProtKB.::GO:0045169; C:fusome; IDA:FlyBase.::GO:0016328; C:lateral plasma membrane; IDA:FlyBase.::GO:0031594; C:neuromuscular junction; IDA:FlyBase.::GO:0005918; C:septate junction; IDA:FlyBase.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005179; F:hormone activity; IDA:UniProtKB.
GO:0030714; P:anterior/posterior axis specification, follicular epithelium; IMP:BHF-UCL.::GO:0022402; P:cell cycle process; IMP:FlyBase.::GO:0060581; P:cell fate commitment involved in pattern specification; IMP:BHF-UCL.::GO:0001708; P:cell fate specification; IMP:BHF-UCL.::GO:0000902; P:cell morphogenesis; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0045198; P:establishment of epithelial cell apical/basal polarity; IMP:FlyBase.::GO:0001737; P:establishment of imaginal disc-derived wing hair orientation; IMP:FlyBase.::GO:0016332; P:establishment or maintenance of polarity of embryonic epithelium; TAS:FlyBase.::GO:0016336; P:establishment or maintenance of polarity of larval imaginal disc epithelium; IMP:FlyBase.::GO:0072002; P:Malpighian tubule development; IMP:FlyBase.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:FlyBase.::GO:0045571; P:negative regulation of imaginal disc growth; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0042048; P:olfactory behavior; IMP:FlyBase.::GO:0007318; P:pole plasm protein localization; IMP:BHF-UCL.::GO:0045823; P:positive regulation of heart contraction; IDA:UniProtKB.::GO:0007464; P:R3/R4 cell fate commitment; IMP:FlyBase.::GO:0051726; P:regulation of cell cycle; NAS:FlyBase.::GO:0030100; P:regulation of endocytosis; IMP:FlyBase.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:BHF-UCL.::GO:0046425; P:regulation of JAK-STAT cascade; IMP:BHF-UCL.::GO:0008593; P:regulation of Notch signaling pathway; IMP:BHF-UCL.::GO:0050803; P:regulation of synapse structure and activity; IMP:FlyBase.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.::GO:0019991; P:septate junction assembly; IMP:FlyBase.::GO:0048863; P:stem cell differentiation; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IMP:FlyBase.::GO:0045186; P:zonula adherens assembly; IMP:FlyBase.
51Q4R3P6    602   LRC40_MACFA Leucine-rich repeat-containing pr...1301.5     35.4     29     44
52Q9C8M9    719   SRF6_ARATH Protein STRUBBELIG-RECEPTOR FAMILY...1390.009     42.4     29     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
53Q8CHE4    1687   PHLP1_MOUSE PH domain leucine-rich repeat-con...2110.01     42.4     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
54Q0P5X1    1673   LRIQ1_MOUSE Leucine-rich repeat and IQ domain...2140.01     42.4     30     49
55Q9DD78    793   TLR21_CHICK Toll-like receptor 2 type-1 OS=Ga...2960.012     42     27     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0035681; P:toll-like receptor 15 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
56Q9LRT1    1016   Y3804_ARATH Probably inactive leucine-rich re...2310.012     42     29     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
57P13605    376   FMOD_BOVIN Fibromodulin OS=Bos taurus (Bovine...2130.014     41.6     26     44GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
58Q9ZUI0    980   Y2241_ARATH Putative leucine-rich repeat rece...1730.015     42     32     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
59P51887    380   FMOD_CHICK Fibromodulin OS=Gallus gallus (Chi...824.4     33.5     30     55GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
60P51884    338   LUM_HUMAN Lumican OS=Homo sapiens (Human). GN...1440.82     35.8     27     47GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005583; C:fibrillar collagen; IDA:UniProtKB.
GO:0005518; F:collagen binding; IDA:UniProtKB.::GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
GO:0030199; P:collagen fibril organization; NAS:UniProtKB.::GO:0007601; P:visual perception; TAS:ProtInc.
61Q15399    786   TLR1_HUMAN Toll-like receptor 1 OS=Homo sapie...2170.02     41.2     27     45GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0035354; C:Toll-like receptor 1-Toll-like receptor 2 protein complex; IDA:MGI.
GO:0046982; F:protein heterodimerization activity; IDA:MGI.::GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
GO:0071727; P:cellular response to triacyl bacterial lipopeptide; IDA:MGI.::GO:0042495; P:detection of triacyl bacterial lipopeptide; IDA:MGI.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; ISS:UniProtKB.::GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; ISS:UniProtKB.
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