Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER007W
Length:
518
Number of sequences:
5887
Description:
YER007W PAC2 SGDID:S000000809, Chr V from 164527-166083, Genome Release 64-1-1, Verified ORF, "Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q6ZQY2    391   YV012_HUMAN Leucine-rich repeat-containing pr...1232.5     34.3     28     49
212Q9FN94    868   RLK7_ARATH Receptor-like protein kinase At5g5...772.6     34.7     35     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC.
213Q01631    2300   CYAA_NEUCR Adenylate cyclase OS=1257 / FGSC 9...699.1     32.7     38     54
GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
214Q8NEP3    725   DAAF1_HUMAN Dynein assembly factor 1, axonema...1232.9     34.3     32     54GO:0035085; C:cilium axoneme; IDA:UniProtKB.::GO:0005737; C:cytoplasm; NAS:BHF-UCL.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0045502; F:dynein binding; IMP:UniProtKB.
GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.::GO:0003341; P:cilium movement; IMP:BHF-UCL.::GO:0044458; P:motile cilium assembly; IMP:BHF-UCL.
215Q68CR7    880   LRC66_HUMAN Leucine-rich repeat-containing pr...1792.9     34.3     29     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
216Q96L50    414   LLR1_HUMAN Leucine-rich repeat protein 1 OS=H...1223     34.3     29     51
217Q3UVD5    967   LGR6_MOUSE Leucine-rich repeat-containing G-p...733     34.3     38     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016500; F:protein-hormone receptor activity; IEA:InterPro.
218P32336    851   NUD1_YEAST Protein NUD1 OS=Saccharomyces cere...1399.4     32.7     31     55GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005200; F:structural constituent of cytoskeleton; IPI:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; IMP:SGD.::GO:0045132; P:meiotic chromosome segregation; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
219P08678    2026   CYAA_YEAST Adenylate cyclase OS=Saccharomyces...1563.2     34.3     30     46GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0004016; F:adenylate cyclase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
220P17778    409   YOPM_YERPE Outer membrane protein yopM OS=Yer...1753.2     33.9     26     43GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
221P49185    411   MK08_RAT Mitogen-activated protein kinase 8 O...1613.3     33.9     25     42GO:0033267; C:axon part; IDA:RGD.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0032839; C:dendrite cytoplasm; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0031982; C:vesicle; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:RGD.
GO:0006954; P:inflammatory response; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; IDA:RGD.::GO:0031175; P:neuron projection development; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IEP:RGD.::GO:0030335; P:positive regulation of cell migration; IDA:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0031116; P:positive regulation of microtubule polymerization; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:RGD.::GO:0009408; P:response to heat; IDA:RGD.::GO:0042542; P:response to hydrogen peroxide; IDA:RGD.::GO:0006970; P:response to osmotic stress; IDA:RGD.::GO:0048545; P:response to steroid hormone stimulus; IEP:RGD.
222Q8K375    552   LRC56_MOUSE Leucine-rich repeat-containing pr...1403.4     33.9     32     46
223P10775    456   RINI_PIG Ribonuclease inhibitor OS=Sus scrofa...993.4     33.9     33     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
224Q8SU52    493   CCR4_ENCCU Probable glucose-repressible alcoh...1043.5     33.9     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
225P45983    427   MK08_HUMAN Mitogen-activated protein kinase 8...1623.6     33.9     25     41GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0035033; F:histone deacetylase regulator activity; IMP:BHF-UCL.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0090045; P:positive regulation of deacetylase activity; IMP:BHF-UCL.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0032880; P:regulation of protein localization; IDA:BHF-UCL.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0009411; P:response to UV; IDA:MGI.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
226Q9DAM1    415   LRC34_MOUSE Leucine-rich repeat-containing pr...1863.7     33.9     25     44
227Q91Y86    384   MK08_MOUSE Mitogen-activated protein kinase 8...1623.7     33.9     25     41GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0031558; P:induction of apoptosis in response to chemical stimulus; IGI:MGI.::GO:0001503; P:ossification; IMP:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IMP:MGI.::GO:2000017; P:positive regulation of determination of dorsal identity; IDA:MGI.::GO:0046686; P:response to cadmium ion; IGI:MGI.
228Q55CS7    834   MPL1_DICDI MAP kinase phosphatase with leucin...2283.7     33.9     26     43GO:0005576; C:extracellular region; IC:dictyBase.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IMP:dictyBase.
GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.
229Q54M77    1867   ROCO8_DICDI Probable serine/threonine-protein...1684     33.9     30     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
230Q9CRC8    602   LRC40_MOUSE Leucine-rich repeat-containing pr...2154.1     33.9     25     45
231Q2V898    841   TLR4_BOSTR Toll-like receptor 4 OS=Boselaphus...1784.1     33.9     24     45GO:0005622; C:intracellular; IEA:InterPro.::GO:0046696; C:lipopolysaccharide receptor complex; ISS:UniProtKB.
GO:0001875; F:lipopolysaccharide receptor activity; ISS:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0032497; P:detection of lipopolysaccharide; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
232Q5VUJ6    765   LRCH2_HUMAN Leucine-rich repeat and calponin ...1384.2     33.9     36     52
233P45969    326   YNZ9_CAEEL Uncharacterized protein T09A5.9 OS...2214.5     33.5     29     46
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
234Q8BU40    982   NAL4A_MOUSE NACHT, LRR and PYD domains-contai...3084.6     33.9     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
235Q3UMG5    773   LRCH2_MOUSE Leucine-rich repeat and calponin ...1384.7     33.9     36     53
236O15455    904   TLR3_HUMAN Toll-like receptor 3 OS=Homo sapie...1524.9     33.5     30     45GO:0036020; C:endolysosome membrane; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
GO:0007250; P:activation of NF-kappaB-inducing kinase activity; NAS:UniProtKB.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0042742; P:defense response to bacterium; TAS:ProtInc.::GO:0051607; P:defense response to virus; TAS:BHF-UCL.::GO:0009597; P:detection of virus; NAS:UniProtKB.::GO:0006972; P:hyperosmotic response; NAS:UniProtKB.::GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045671; P:negative regulation of osteoclast differentiation; NAS:UniProtKB.::GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0045356; P:positive regulation of interferon-alpha biosynthetic process; IDA:UniProtKB.::GO:0045359; P:positive regulation of interferon-beta biosynthetic process; IDA:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; ISS:BHF-UCL.::GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:UniProtKB.::GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.::GO:0034123; P:positive regulation of toll-like receptor signaling pathway; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
237Q8QHK8    426   MK08_XENLA Mitogen-activated protein kinase 8...1624.9     33.5     25     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007254; P:JNK cascade; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
238Q09JZ4    432   DAAF1_CHLRE Leucine-rich repeat-containing pr...1415.1     33.5     27     45GO:0044297; C:cell body; IDA:BHF-UCL.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
GO:0070286; P:axonemal dynein complex assembly; IMP:BHF-UCL.::GO:0003341; P:cilium movement; IMP:BHF-UCL.::GO:2000155; P:positive regulation of flagellar cell motility; IMP:BHF-UCL.::GO:0033365; P:protein localization to organelle; IMP:BHF-UCL.::GO:0003356; P:regulation of cilium beat frequency; IMP:BHF-UCL.::GO:0036144; P:regulation of flagellum beat frequency; IMP:BHF-UCL.
239Q91VI7    456   RINI_MOUSE Ribonuclease inhibitor OS=Mus musc...1605.1     33.5     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
240Q4G017    1502   NISCH_RAT Nischarin OS=Rattus norvegicus (Rat...1575.3     33.5     25     45GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0008227; F:G-protein coupled amine receptor activity; IDA:RGD.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IMP:RGD.::GO:0048243; P:norepinephrine secretion; IMP:RGD.::GO:0008217; P:regulation of blood pressure; IMP:RGD.::GO:0032228; P:regulation of synaptic transmission, GABAergic; IMP:RGD.
241O42099    427   MK08B_CYPCA Mitogen-activated protein kinase ...1665.4     33.5     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
records
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