Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER007W
Length:
518
Number of sequences:
5887
Description:
YER007W PAC2 SGDID:S000000809, Chr V from 164527-166083, Genome Release 64-1-1, Verified ORF, "Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151P33076    1130   C2TA_HUMAN MHC class II transactivator OS=Hom...940.48     37     26     47GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0033613; F:activating transcription factor binding; IPI:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0032966; P:negative regulation of collagen biosynthetic process; IC:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0045345; P:positive regulation of MHC class I biosynthetic process; IDA:BHF-UCL.::GO:0045348; P:positive regulation of MHC class II biosynthetic process; IC:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0046677; P:response to antibiotic; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
152Q38SD2    2015   LRRK1_HUMAN Leucine-rich repeat serine/threon...1750.92     36.2     27     44GO:0005739; C:mitochondrion; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
153Q0WR59    1048   Y5020_ARATH Probable inactive receptor kinase...2430.51     37     26     47GO:0005829; C:cytosol; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
154Q9VEK6    641   SUR8_DROME Leucine-rich repeat protein soc-2 ...2170.52     36.6     26     47
155O00206    839   TLR4_HUMAN Toll-like receptor 4 OS=Homo sapie...1390.54     36.6     32     53GO:0009897; C:external side of plasma membrane; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0046696; C:lipopolysaccharide receptor complex; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0001530; F:lipopolysaccharide binding; NAS:UniProtKB.::GO:0001875; F:lipopolysaccharide receptor activity; IDA:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
GO:0000187; P:activation of MAPK activity; ISS:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0050829; P:defense response to Gram-negative bacterium; IC:BHF-UCL.::GO:0016046; P:detection of fungus; NAS:UniProtKB.::GO:0032497; P:detection of lipopolysaccharide; IDA:UniProtKB.::GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:BHF-UCL.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL.::GO:0032689; P:negative regulation of interferon-gamma production; ISS:BHF-UCL.::GO:0032700; P:negative regulation of interleukin-17 production; ISS:BHF-UCL.::GO:0032707; P:negative regulation of interleukin-23 production; ISS:BHF-UCL.::GO:0032715; P:negative regulation of interleukin-6 production; ISS:BHF-UCL.::GO:0045671; P:negative regulation of osteoclast differentiation; NAS:UniProtKB.::GO:0032720; P:negative regulation of tumor necrosis factor production; ISS:BHF-UCL.::GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0032727; P:positive regulation of interferon-alpha production; ISS:BHF-UCL.::GO:0032728; P:positive regulation of interferon-beta production; ISS:BHF-UCL.::GO:0032729; P:positive regulation of interferon-gamma production; ISS:BHF-UCL.::GO:0032732; P:positive regulation of interleukin-1 production; ISS:BHF-UCL.::GO:0032733; P:positive regulation of interleukin-10 production; ISS:BHF-UCL.::GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IDA:UniProtKB.::GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.::GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IDA:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:MGI.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.::GO:0010572; P:positive regulation of platelet activation; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IDA:UniProtKB.::GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.::GO:0042088; P:T-helper 1 type immune response; NAS:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
156Q9TTN0    839   TLR4_PANPA Toll-like receptor 4 OS=Pan panisc...1390.55     36.6     32     53GO:0005622; C:intracellular; IEA:InterPro.::GO:0046696; C:lipopolysaccharide receptor complex; ISS:UniProtKB.
GO:0001875; F:lipopolysaccharide receptor activity; ISS:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0032497; P:detection of lipopolysaccharide; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0042116; P:macrophage activation; ISS:UniProtKB.
157O75427    683   LRCH4_HUMAN Leucine-rich repeat and calponin ...1960.55     36.6     28     45GO:0016605; C:PML body; IDA:MGI.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007399; P:nervous system development; TAS:ProtInc.
158A4D1F6    860   LRRD1_HUMAN Leucine-rich repeat and death dom...1680.75     36.2     28     46
GO:0007165; P:signal transduction; IEA:InterPro.
159Q5RFS7    360   PP1R7_PONAB Protein phosphatase 1 regulatory ...2320.64     36.2     27     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
160Q9ERV7    915   PIDD_MOUSE p53-induced protein with a death d...1880.69     36.6     26     43GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0006915; P:apoptotic process; IDA:MGI.
161Q8SPE8    837   TLR4_GORGO Toll-like receptor 4 OS=Gorilla go...1390.7     36.6     32     53GO:0005622; C:intracellular; IEA:InterPro.::GO:0046696; C:lipopolysaccharide receptor complex; ISS:UniProtKB.
GO:0001875; F:lipopolysaccharide receptor activity; ISS:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0032497; P:detection of lipopolysaccharide; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0042116; P:macrophage activation; ISS:UniProtKB.
162P12024    1315   CHAO_DROME Chaoptin OS=Drosophila melanogaste...2280.72     36.6     27     43GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0007156; P:homophilic cell adhesion; IDA:FlyBase.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042052; P:rhabdomere development; IGI:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
163Q3U3V8    786   XRRA1_MOUSE X-ray radiation resistance-associ...1330.73     36.2     29     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0010165; P:response to X-ray; ISS:UniProtKB.
164Q9JJ28    1271   FLII_MOUSE Protein flightless-1 homolog OS=Mu...1510.73     36.6     28     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; TAS:MGI.::GO:0051014; P:actin filament severing; TAS:MGI.::GO:0007275; P:multicellular organismal development; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
165Q7L1W4    858   LRC8D_HUMAN Leucine-rich repeat-containing pr...2370.74     36.2     25     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
166Q9FG24    735   SRF2_ARATH Protein STRUBBELIG-RECEPTOR FAMILY...1660.75     36.2     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
167Q3SYS4    643   DAAF1_BOVIN Dynein assembly factor 1, axonema...1770.76     36.2     27     47GO:0035085; C:cilium axoneme; ISS:UniProtKB.
GO:0045502; F:dynein binding; ISS:UniProtKB.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
168Q8BMT4    693   LRC33_MOUSE Leucine-rich repeat-containing pr...1983.2     34.3     25     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
169Q9NR97    1041   TLR8_HUMAN Toll-like receptor 8 OS=Homo sapie...1812     35     26     45GO:0036020; C:endolysosome membrane; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IC:UniProtKB.
GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0004872; F:receptor activity; NAS:UniProtKB.::GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0016064; P:immunoglobulin mediated immune response; TAS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; NAS:UniProtKB.::GO:0045089; P:positive regulation of innate immune response; IDA:UniProtKB.::GO:0045356; P:positive regulation of interferon-alpha biosynthetic process; IDA:UniProtKB.::GO:0045359; P:positive regulation of interferon-beta biosynthetic process; IDA:UniProtKB.::GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:UniProtKB.::GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IMP:UniProtKB.
170C0LGS2    1136   Y4361_ARATH Probable LRR receptor-like serine...1730.88     36.2     29     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
171P84329    595   HFW1_DROPS Protein halfway OS=Drosophila pseu...1460.89     35.8     26     40GO:0005622; C:intracellular; ISS:GOC.
GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.::GO:0035073; P:pupariation; ISS:UniProtKB.::GO:0035075; P:response to ecdysone; ISS:UniProtKB.
172Q5TJ59    904   TLR3_BOVIN Toll-like receptor 3 OS=Bos taurus...1520.9     36.2     28     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
173Q6AYH9    633   DAAF1_RAT Dynein assembly factor 1, axonemal ...1200.9     35.8     31     53GO:0035085; C:cilium axoneme; ISS:UniProtKB.
GO:0045502; F:dynein binding; ISS:UniProtKB.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
174Q9FN93    887   Y5596_ARATH Probable LRR receptor-like serine...790.93     36.2     39     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
175Q9D9B4    229   CJ011_MOUSE Leucine-rich repeat-containing pr...1720.94     35     29     44
176Q8BXA7    1320   PHLP2_MOUSE PH domain leucine-rich repeat-con...1611     35.8     31     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
177Q9D2H9    634   DAAF1_MOUSE Dynein assembly factor 1, axonema...1251     35.8     30     51GO:0035085; C:cilium axoneme; ISS:UniProtKB.
GO:0045502; F:dynein binding; ISS:UniProtKB.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
178Q8VDB8    371   LRRC2_MOUSE Leucine-rich repeat-containing pr...1441     35.4     31     44
179Q8ZQQ2    765   SLRP_SALTY E3 ubiquitin-protein ligase slrP O...1841     35.8     24     45GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0009405; P:pathogenesis; IDA:UniProtKB.::GO:0030254; P:protein secretion by the type III secretion system; ISS:UniProtKB.
180Q1X8D7    754   LRC36_HUMAN Leucine-rich repeat-containing pr...981.1     35.8     33     55
181Q9Z1P4    907   LGR5_MOUSE Leucine-rich repeat-containing G-p...731.1     35.8     36     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016500; F:protein-hormone receptor activity; IEA:InterPro.
GO:0048839; P:inner ear development; IDA:MGI.
records
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