UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER007W

Length:

518

Number of sequences:

5887

Description:

YER007W PAC2 SGDID:S000000809, Chr V from 164527-166083, Genome Release 64-1-1, Verified ORF, "Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
121	A8JAM0	1159	CC135_CHLRE Coiled-coil domain-containing pro...	201	0.23	38.1	27	45	GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0019861; C:flagellum; IDA:UniProtKB.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001539; P:ciliary or flagellar motility; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
122	C0LGW6	966	ERL1_ARATH LRR receptor-like serine/threonine...	254	0.26	37.7	28	45	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
									GO:0010103; P:stomatal complex morphogenesis; IGI:TAIR.
123	Q01513	2145	CYAA_PODAS Adenylate cyclase OS=Podospora ans...	239	0.27	37.7	26	47
									GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0035556; P:intracellular signal transduction; IEA:InterPro.
124	Q13045	1269	FLII_HUMAN Protein flightless-1 homolog OS=Ho...	151	0.27	37.7	28	51	GO:0005813; C:centrosome; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0003779; F:actin binding; TAS:ProtInc.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006936; P:muscle contraction; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
125	Q9ZWC8	1166	BRL1_ARATH Serine/threonine-protein kinase BR...	189	0.27	37.7	30	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
126	Q3V1N1	1048	MFHA1_MOUSE Malignant fibrous histiocytoma-am...	245	0.29	37.7	28	46
127	Q54WS5	2147	ROCO6_DICDI Probable serine/threonine-protein...	87	0.3	37.7	36	56	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
128	O60602	858	TLR5_HUMAN Toll-like receptor 5 OS=Homo sapie...	136	7.4	33.1	29	43	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0005149; F:interleukin-1 receptor binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
									GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0034123; P:positive regulation of toll-like receptor signaling pathway; IDA:BHF-UCL.
129	Q0PV50	904	TLR3_BOSTR Toll-like receptor 3 OS=Boselaphus...	123	0.31	37.7	31	48	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
130	O94769	699	ECM2_HUMAN Extracellular matrix protein 2 OS=...	108	0.31	37.4	32	50
									GO:0005178; F:integrin binding; TAS:ProtInc.
									GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
131	Q29KL8	1582	DAAF1_DROPS Dynein assembly factor 1, axonema...	132	0.32	37.7	30	50	GO:0035085; C:cilium axoneme; ISS:UniProtKB.
									GO:0045502; F:dynein binding; ISS:UniProtKB.
									GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
132	Q9FIZ3	1252	GSO2_ARATH LRR receptor-like serine/threonine...	215	0.33	37.7	29	46	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
									GO:0009790; P:embryo development; IGI:TAIR.::GO:0009553; P:embryo sac development; IMP:TAIR.::GO:0008544; P:epidermis development; IGI:TAIR.
133	Q501X2	532	CEP72_DANRE Centrosomal protein of 72 kDa OS=...	117	0.35	37.4	35	51	GO:0005813; C:centrosome; ISS:UniProtKB.
									GO:0033566; P:gamma-tubulin complex localization; ISS:UniProtKB.::GO:0007051; P:spindle organization; ISS:UniProtKB.
134	B4QVR7	680	SUR8_DROSI Leucine-rich repeat protein soc-2 ...	217	0.35	37.4	26	47
135	Q65Z91	369	TSK_CHICK Tsukushin OS=Gallus gallus (Chicken...	140	0.36	37	34	49	GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
136	Q9DE67	343	LUM_COTJA Lumican OS=Coturnix coturnix japoni...	181	0.37	37	28	45	GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
137	Q7ZV84	555	DAAF1_DANRE Dynein assembly factor 1, axonema...	135	0.38	37	30	50	GO:0035085; C:cilium axoneme; ISS:UniProtKB.
									GO:0045502; F:dynein binding; IMP:UniProtKB.
									GO:0003305; P:cell migration involved in heart jogging; IMP:ZFIN.::GO:0001539; P:ciliary or flagellar motility; IMP:ZFIN.::GO:0035083; P:cilium axoneme assembly; IMP:ZFIN.::GO:0060027; P:convergent extension involved in gastrulation; IMP:ZFIN.::GO:0001947; P:heart looping; IMP:ZFIN.::GO:0003314; P:heart rudiment morphogenesis; IMP:ZFIN.::GO:0048793; P:pronephros development; IMP:ZFIN.
138	Q9Z2H4	951	LGR4_RAT Leucine-rich repeat-containing G-pro...	180	6.2	33.5	27	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016500; F:protein-hormone receptor activity; IEA:InterPro.
139	Q4R6F0	863	LRRD1_MACFA Leucine-rich repeat and death dom...	168	0.38	37.4	29	46
									GO:0007165; P:signal transduction; IEA:InterPro.
140	Q6P4K6	1129	S11IP_XENTR Serine/threonine-protein kinase 1...	262	0.38	37.4	25	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
141	P51890	343	LUM_CHICK Lumican OS=Gallus gallus (Chicken)....	181	0.4	36.6	28	45
142	Q9HBX8	967	LGR6_HUMAN Leucine-rich repeat-containing G-p...	73	0.42	37.4	40	53	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016500; F:protein-hormone receptor activity; IEA:InterPro.
143	Q6GPJ5	605	LRC40_XENLA Leucine-rich repeat-containing pr...	220	0.42	37	27	43
144	Q6PCJ1	1232	DCTN1_XENLA Dynactin subunit 1 OS=Xenopus lae...	70	0.43	37.4	33	59	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
									GO:0003774; F:motor activity; IEA:UniProtKB-KW.
145	P14605	1692	CYAA_SCHPO Adenylate cyclase OS=Schizosacchar...	122	0.43	37.4	33	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; NAS:PomBase.
									GO:0004016; F:adenylate cyclase activity; IMP:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; NAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; TAS:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; NAS:PomBase.
146	D0ZRB2	765	SLRP_SALT1 E3 ubiquitin-protein ligase slrP O...	184	0.44	37	24	45	GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
									GO:0009405; P:pathogenesis; ISS:UniProtKB.::GO:0030254; P:protein secretion by the type III secretion system; IDA:UniProtKB.
147	Q54TM7	1288	DRKD_DICDI Probable serine/threonine-protein ...	119	0.44	37	30	52
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
148	Q5ZLN0	603	LRC40_CHICK Leucine-rich repeat-containing pr...	191	0.44	37	28	41
149	B4PU77	645	SUR8_DROYA Leucine-rich repeat protein soc-2 ...	217	0.46	37	26	47
150	Q6UY01	552	LRC31_HUMAN Leucine-rich repeat-containing pr...	84	0.47	37	36	55
151	P33076	1130	C2TA_HUMAN MHC class II transactivator OS=Hom...	94	0.48	37	26	47	GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0033613; F:activating transcription factor binding; IPI:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
									GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0032966; P:negative regulation of collagen biosynthetic process; IC:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0045345; P:positive regulation of MHC class I biosynthetic process; IDA:BHF-UCL.::GO:0045348; P:positive regulation of MHC class II biosynthetic process; IC:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0046677; P:response to antibiotic; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.

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