Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER007W
Length:
518
Number of sequences:
5887
Description:
YER007W PAC2 SGDID:S000000809, Chr V from 164527-166083, Genome Release 64-1-1, Verified ORF, "Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P39937    518   PAC2_YEAST Protein PAC2 OS=Saccharomyces cere...5180     1047     100     100GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0043014; F:alpha-tubulin binding; IPI:SGD.
GO:0006457; P:protein folding; IGI:SGD.
2Q5U508    522   TBCE_XENLA Tubulin-specific chaperone E OS=Xe...5332e-40     157     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:UniProtKB.
3Q8CIV8    524   TBCE_MOUSE Tubulin-specific chaperone E OS=Mu...5367e-34     137     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0051082; F:unfolded protein binding; TAS:MGI.
GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0000226; P:microtubule cytoskeleton organization; IMP:MGI.::GO:0014889; P:muscle atrophy; IMP:MGI.::GO:0048936; P:peripheral nervous system neuron axonogenesis; IMP:MGI.::GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0007021; P:tubulin complex assembly; TAS:MGI.
4Q5RBD9    527   TBCE_PONAB Tubulin-specific chaperone E OS=Po...5381e-33     137     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:UniProtKB.
5Q15813    527   TBCE_HUMAN Tubulin-specific chaperone E OS=Ho...5382e-33     135     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; TAS:ProtInc.
GO:0051087; F:chaperone binding; TAS:ProtInc.
GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.::GO:0007023; P:post-chaperonin tubulin folding pathway; IDA:UniProtKB.
6Q32KS0    528   TBCE_BOVIN Tubulin-specific chaperone E OS=Bo...5403e-32     132     25     45GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0007023; P:post-chaperonin tubulin folding pathway; TAS:Reactome.
7Q5FVQ9    524   TBCE_RAT Tubulin-specific chaperone E OS=Ratt...5408e-32     131     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:UniProtKB.
8Q5U378    521   TBCE_DANRE Tubulin-specific chaperone E OS=Da...5271e-21     102     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:UniProtKB.
9Q10303    511   ALP21_SCHPO Cell polarity protein alp21 OS=Sc...3770.00000000000003     78.6     26     48GO:0005829; C:cytosol; IDA:PomBase.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0043014; F:alpha-tubulin binding; IPI:PomBase.
GO:0007017; P:microtubule-based process; NAS:PomBase.::GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:PomBase.
10Q55CN0    525   TBCE_DICDI Tubulin-specific chaperone E OS=Di...3780.000000000002     73.2     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
11Q9R1F8    784   TLR2_CRIGR Toll-like receptor 2 OS=Cricetulus...2300.0000000002     67.4     29     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
12Q5QJ74    424   TBCEL_HUMAN Tubulin-specific chaperone cofact...3770.00000001     60.8     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
13A1A4H9    521   LRRT1_BOVIN Leucine-rich repeat transmembrane...1880.00000002     60.5     27     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
14Q86UE6    522   LRRT1_HUMAN Leucine-rich repeat transmembrane...1880.00000002     60.1     27     53GO:0030424; C:axon; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
15Q8K377    522   LRRT1_MOUSE Leucine-rich repeat transmembrane...1880.00000003     60.1     27     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
16Q5PQJ7    424   TBCEL_RAT Tubulin-specific chaperone cofactor...3750.00000003     59.3     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
17Q5R6B1    522   LRRT1_PONAB Leucine-rich repeat transmembrane...1880.0000001     58.2     26     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
18Q9QUN7    784   TLR2_MOUSE Toll-like receptor 2 OS=Mus muscul...1880.0000002     57.4     30     50GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0035355; C:Toll-like receptor 2-Toll-like receptor 6 protein complex; IPI:MGI.
GO:0042498; F:diacyl lipopeptide binding; IDA:MGI.::GO:0070891; F:lipoteichoic acid binding; IDA:MGI.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.::GO:0042497; F:triacyl lipopeptide binding; IDA:MGI.
GO:0002752; P:cell surface pattern recognition receptor signaling pathway; IMP:MGI.::GO:0071221; P:cellular response to bacterial lipopeptide; TAS:BHF-UCL.::GO:0071223; P:cellular response to lipoteichoic acid; IMP:MGI.::GO:0071224; P:cellular response to peptidoglycan; IMP:MGI.::GO:0042892; P:chloramphenicol transport; IMP:MGI.::GO:0050830; P:defense response to Gram-positive bacterium; IMP:MGI.::GO:0052063; P:induction by symbiont of defense-related host nitric oxide production; IMP:MGI.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; IGI:MGI.::GO:0044130; P:negative regulation of growth of symbiont in host; IMP:MGI.::GO:0032695; P:negative regulation of interleukin-12 production; IMP:MGI.::GO:0032700; P:negative regulation of interleukin-17 production; IMP:MGI.::GO:0032722; P:positive regulation of chemokine production; IMP:MGI.::GO:0050715; P:positive regulation of cytokine secretion; IGI:MGI.::GO:0032728; P:positive regulation of interferon-beta production; IDA:BHF-UCL.::GO:0032735; P:positive regulation of interleukin-12 production; IDA:BHF-UCL.::GO:0032741; P:positive regulation of interleukin-18 production; IDA:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.::GO:0002687; P:positive regulation of leukocyte migration; IMP:MGI.::GO:0060907; P:positive regulation of macrophage cytokine production; IMP:MGI.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:MGI.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IMP:MGI.::GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:BHF-UCL.::GO:0002238; P:response to molecule of fungal origin; IMP:MGI.
19Q8C0R9    853   LRRD1_MOUSE Leucine-rich repeat and death dom...1370.34     37.4     34     53
20Q8C5W3    424   TBCEL_MOUSE Tubulin-specific chaperone cofact...3770.00002     50.4     25     44GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.
21Q9Y4C4    1052   MFHA1_HUMAN Malignant fibrous histiocytoma-am...2490.00008     49.3     28     45
22Q9DGB6    781   TLR22_CHICK Toll-like receptor 2 type-2 OS=Ga...2930.0001     48.5     26     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0042494; P:detection of bacterial lipoprotein; NAS:Roslin.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0002224; P:toll-like receptor signaling pathway; NAS:AgBase.
23Q05091    330   PGIP_PYRCO Polygalacturonase inhibitor OS=Pyr...1520.0004     46.2     34     51GO:0048046; C:apoplast; IEA:UniProtKB-SubCell.::GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.
24Q8BZ81    582   LRRT3_MOUSE Leucine-rich repeat transmembrane...1730.0005     46.6     28     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
25P18009    574   IPA4_SHIFL Probable E3 ubiquitin-protein liga...1540.0005     46.6     31     48GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
26Q9BGP6    581   LRRT3_MACFA Leucine-rich repeat transmembrane...1730.0005     46.6     28     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
27Q86VH5    581   LRRT3_HUMAN Leucine-rich repeat transmembrane...1730.0005     46.6     28     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
28P0CE12    788   SSPH2_SALTY E3 ubiquitin-protein ligase sspH2...1590.47     37     27     46GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0009405; P:pathogenesis; ISS:UniProtKB.::GO:0030254; P:protein secretion by the type III secretion system; ISS:UniProtKB.
29D0ZPH9    788   SSPH2_SALT1 E3 ubiquitin-protein ligase sspH2...1590.47     37     27     46GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0009405; P:pathogenesis; IDA:UniProtKB.::GO:0030254; P:protein secretion by the type III secretion system; IDA:UniProtKB.
30Q5BK65    692   LRC33_RAT Leucine-rich repeat-containing prot...1995.2     33.5     24     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
31B2LT65    784   TLR2_SHEEP Toll-like receptor 2 OS=Ovis aries...1382     35     33     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
records
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