Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YEL062W
Length:
615
Number of sequences:
5887
Description:
YEL062W NPR2 SGDID:S000000788, Chr V from 34407-36254, Genome Release 64-1-1, Verified ORF, "Subunit of the conserved Npr2/3 complex that mediates downregulation of TORC1 activity upon amino acid limitation; subunit of SEA (Seh1-associated) complex; homolog of human NPRL2; target of Grr1p; required for growth on urea and proline"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P39923    615   NPR2_YEAST Nitrogen permease regulator 2 OS=S...6150     1252     100     100GO:0097042; C:extrinsic to fungal-type vacuolar membrane; IDA:SGD.::GO:0035859; C:Seh1-associated complex; IDA:SGD.
GO:0034198; P:cellular response to amino acid starvation; IMP:SGD.::GO:0006995; P:cellular response to nitrogen starvation; IMP:SGD.::GO:0015824; P:proline transport; IMP:SGD.::GO:0032006; P:regulation of TOR signaling cascade; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0042493; P:response to drug; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0015840; P:urea transport; IMP:SGD.
2O42857    409   NPR2_SCHPO Nitrogen permease regulator 2 homo...960.0003     47.4     32     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0034198; P:cellular response to amino acid starvation; ISS:PomBase.::GO:0070881; P:regulation of proline transport; ISS:PomBase.::GO:0032006; P:regulation of TOR signaling cascade; ISS:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q8WTW4    380   NPRL2_HUMAN Nitrogen permease regulator 2-lik...563.4     34.3     36     54GO:0005737; C:cytoplasm; IDA:HPA.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; IDA:UniProtKB.
GO:0033673; P:negative regulation of kinase activity; IDA:UniProtKB.
4Q5E9U9    380   NPRL2_BOVIN Nitrogen permease regulator 2-lik...600.97     35.8     35     53
5Q9WUE4    380   NPRL2_MOUSE Nitrogen permease regulator 2-lik...601.2     35.8     35     53
6Q2GYD8    2043   ATG2_CHAGB Autophagy-related protein 2 OS=634...1190.97     36.6     27     44GO:0005770; C:late endosome; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
7Q96QB1    1528   RHG07_HUMAN Rho GTPase-activating protein 7 O...837.2     33.5     31     47GO:0005901; C:caveola; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.::GO:0030900; P:forebrain development; ISS:UniProtKB.::GO:0003007; P:heart morphogenesis; ISS:UniProtKB.::GO:0021575; P:hindbrain morphogenesis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0035024; P:negative regulation of Rho protein signal transduction; IMP:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; IDA:UniProtKB.::GO:0001843; P:neural tube closure; ISS:UniProtKB.::GO:0035307; P:positive regulation of protein dephosphorylation; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
8D2HNY3    1025   FAN1_AILME Fanconi-associated nuclease 1 OS=A...408.6     33.1     38     60GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008409; F:5'-3' exonuclease activity; ISS:UniProtKB.::GO:0017108; F:5'-flap endonuclease activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004528; F:phosphodiesterase I activity; IEA:EC.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.
GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0033683; P:nucleotide-excision repair, DNA incision; ISS:UniProtKB.
records
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