Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YEL060C
Length:
635
Number of sequences:
5887
Description:
YEL060C PRB1 SGDID:S000000786, Chr V from 41953-40046, Genome Release 64-1-1, reverse complement, Verified ORF, "Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation; activity inhibited by Pbi2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q6UW60    755   PCSK4_HUMAN Proprotein convertase subtilisin/...1030.021     41.6     32     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0006508; P:proteolysis; IBA:RefGenome.
212P0DD35    1169   C5AP_STRPQ C5a peptidase OS=Streptococcus pyo...960.03     41.2     33     53GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
213P0DD34    1169   C5AP_STRP3 C5a peptidase OS=Streptococcus pyo...960.03     41.2     33     53GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
214Q5X9R0    1184   C5AP_STRP6 C5a peptidase OS=Streptococcus pyo...960.031     41.2     33     53GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
215P15926    1167   C5AP_STRPY C5a peptidase OS=Streptococcus pyo...960.032     41.2     33     53GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
216P58099    1181   C5AP_STRP1 C5a peptidase OS=Streptococcus pyo...960.036     41.2     33     53GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
217P29120    753   NEC1_HUMAN Neuroendocrine convertase 1 OS=Hom...2530.038     40.8     25     38GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IBA:RefGenome.::GO:0030141; C:secretory granule; TAS:Reactome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; ISS:BHF-UCL.
GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0043043; P:peptide biosynthetic process; ISS:BHF-UCL.::GO:0016486; P:peptide hormone processing; TAS:Reactome.::GO:0006508; P:proteolysis; TAS:ProtInc.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
218Q9LLL8    749   XSP1_ARATH Xylem serine proteinase 1 OS=Arabi...560.046     40.4     43     54GO:0009505; C:plant-type cell wall; IDA:TAIR.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
219P09231    756   KEX1A_KLULA Protease KEX1 OS=1267 / NRRL Y-11...2390.048     40.4     26     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
220P28840    752   NEC1_RAT Neuroendocrine convertase 1 OS=Rattu...2530.054     40.4     25     38GO:0043679; C:axon terminus; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0005802; C:trans-Golgi network; IDA:RGD.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0051087; F:chaperone binding; IPI:RGD.::GO:0043559; F:insulin binding; IPI:RGD.::GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0009790; P:embryo development; IEP:RGD.::GO:0022008; P:neurogenesis; IEP:RGD.::GO:0031016; P:pancreas development; IEP:RGD.::GO:0016486; P:peptide hormone processing; IDA:RGD.::GO:0021983; P:pituitary gland development; IEP:RGD.::GO:0050714; P:positive regulation of protein secretion; IDA:RGD.::GO:0016540; P:protein autoprocessing; IMP:RGD.::GO:0006508; P:proteolysis; IMP:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0010157; P:response to chlorate; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0070555; P:response to interleukin-1; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.
221P63240    753   NEC1_MUSCO Neuroendocrine convertase 1 OS=Mus...2530.055     40.4     25     38GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
222P63239    753   NEC1_MOUSE Neuroendocrine convertase 1 OS=Mus...2530.06     40     25     38GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IBA:RefGenome.::GO:0030141; C:secretory granule; TAS:Reactome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
223Q9GLR1    753   NEC1_BOVIN Neuroendocrine convertase 1 OS=Bos...980.15     38.9     30     45GO:0005615; C:extracellular space; ISS:RefGenome.::GO:0005794; C:Golgi apparatus; ISS:RefGenome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
224O64495    775   SDD1_ARATH Subtilisin-like protease SDD1 OS=A...1530.16     38.9     29     42GO:0048046; C:apoplast; IEA:UniProtKB-SubCell.::GO:0009897; C:external side of plasma membrane; IDA:TAIR.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; IMP:TAIR.::GO:0010103; P:stomatal complex morphogenesis; IMP:TAIR.
225P51559    943   BLI4_CAEEL Endoprotease bli-4 OS=Caenorhabdit...2560.3     38.1     27     40GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
226P26016    1269   FUR11_DROME Furin-like protease 1, isoforms 1...3100.42     37.7     23     38GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0004252; F:serine-type endopeptidase activity; IDA:FlyBase.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
227P30430    1101   FUR1C_DROME Furin-like protease 1, isoform 1-...1550.65     37     25     42GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0004252; F:serine-type endopeptidase activity; IDA:FlyBase.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
228P30199    461   EPIP_STAEP Epidermin leader peptide-processin...2960.7     36.6     25     36
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
229Q04592    1877   PCSK5_MOUSE Proprotein convertase subtilisin/...2540.91     36.6     23     40GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030141; C:secretory granule; IDA:MGI.
GO:0042277; F:peptide binding; IDA:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
GO:0009952; P:anterior/posterior pattern specification; IMP:BHF-UCL.::GO:0042089; P:cytokine biosynthetic process; IDA:BHF-UCL.::GO:0007566; P:embryo implantation; IMP:BHF-UCL.::GO:0048566; P:embryonic digestive tract development; IMP:BHF-UCL.::GO:0048706; P:embryonic skeletal system development; IMP:BHF-UCL.::GO:0007507; P:heart development; IMP:BHF-UCL.::GO:0001822; P:kidney development; IMP:BHF-UCL.::GO:0035108; P:limb morphogenesis; IMP:BHF-UCL.::GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030323; P:respiratory tube development; IMP:BHF-UCL.::GO:0019067; P:viral assembly, maturation, egress, and release; IDA:BHF-UCL.
230P41413    1809   PCSK5_RAT Proprotein convertase subtilisin/ke...2541.2     36.2     23     40GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005794; C:Golgi apparatus; IBA:RefGenome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0007565; P:female pregnancy; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
231P83610    62   ALP_FUSCU Alkaline proteinase OS=Fusarium cul...271.4     33.1     44     67GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
232B9JC68    134   RPOZ_AGRRK DNA-directed RNA polymerase subuni...431.6     33.9     37     53GO:0030880; C:RNA polymerase complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
233P29122    969   PCSK6_HUMAN Proprotein convertase subtilisin/...1161.6     35.8     27     43GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0031012; C:extracellular matrix; IDA:BHF-UCL.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005796; C:Golgi lumen; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005625; C:soluble fraction; IDA:BHF-UCL.
GO:0043499; F:eukaryotic cell surface binding; IDA:BHF-UCL.::GO:0008201; F:heparin binding; IDA:BHF-UCL.::GO:0048406; F:nerve growth factor binding; IDA:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
GO:0009100; P:glycoprotein metabolic process; IDA:BHF-UCL.::GO:0032455; P:nerve growth factor processing; TAS:Reactome.::GO:0032902; P:nerve growth factor production; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030510; P:regulation of BMP signaling pathway; TAS:BHF-UCL.::GO:0032940; P:secretion by cell; IDA:BHF-UCL.
234Q7YJX0    201   RR4_CALFG 30S ribosomal protein S4, chloropla...851.6     34.7     26     45GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0015935; C:small ribosomal subunit; IEA:InterPro.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
235Q63415    937   PCSK6_RAT Proprotein convertase subtilisin/ke...1162.1     35.4     27     43GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005794; C:Golgi apparatus; IBA:RefGenome.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0016486; P:peptide hormone processing; IEP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
236Q06RC7    203   RR4_JASNU 30S ribosomal protein S4, chloropla...552.3     34.3     29     56GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0015935; C:small ribosomal subunit; IEA:InterPro.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
237P15292    1962   P3P_LACLS PIII-type proteinase OS=Lactococcus...522.3     35     44     60GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
238Q02470    1902   P2P_LACPA PII-type proteinase OS=Lactobacillu...522.4     35     44     60GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
239P15293    1902   P2P_LACLC PII-type proteinase OS=Lactococcus ...522.5     35     44     60GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
240P16271    1902   P1P_LACLC PI-type proteinase OS=Lactococcus l...522.5     35     44     60GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
241B5ZW67    134   RPOZ_RHILW DNA-directed RNA polymerase subuni...413.7     32.7     39     56GO:0030880; C:RNA polymerase complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
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