Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YEL060C
Length:
635
Number of sequences:
5887
Description:
YEL060C PRB1 SGDID:S000000786, Chr V from 41953-40046, Genome Release 64-1-1, reverse complement, Verified ORF, "Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation; activity inhibited by Pbi2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181P29141    806   SUBV_BACSU Minor extracellular protease vpr O...550.37     37.7     38     51GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
182P16397    1433   SUBF_BACSU Bacillopeptidase F OS=Bacillus sub...3500.0000005     57     25     39GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004180; F:carboxypeptidase activity; IEA:InterPro.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
183P85156    40   ASE1_ACRSP Subtilisin-like serine protease AS...430.0000006     51.6     53     65
GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
184Q9RYM8    728   SUB2_DEIRA Probable subtilase-type serine pro...1350.000009     52.4     31     49GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
185Q9Z2A8    1052   MBTP1_CRIGR Membrane-bound transcription fact...3200.00008     49.7     27     37GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
186Q9WTZ3    1052   MBTP1_RAT Membrane-bound transcription factor...3200.00008     49.7     27     37GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IDA:RGD.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IBA:RefGenome.
187P29145    710   NECB_HYDVU PC3-like endoprotease variant B OS...2540.0002     48.5     26     36
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
188Q61139    770   PCSK7_MOUSE Proprotein convertase subtilisin/...2160.0002     48.1     27     45GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0016485; P:protein processing; IBA:RefGenome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
189Q14703    1052   MBTP1_HUMAN Membrane-bound transcription fact...2450.0002     48.1     29     39GO:0005788; C:endoplasmic reticulum lumen; TAS:ProtInc.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IBA:RefGenome.
190P29146    793   NECA_HYDVU PC3-like endoprotease variant A OS...2550.0002     48.1     25     36
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
191Q9WTZ2    1052   MBTP1_MOUSE Membrane-bound transcription fact...2450.0002     48.1     29     39GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IDA:MGI.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IBA:RefGenome.::GO:0042990; P:regulation of transcription factor import into nucleus; IDA:MGI.
192Q62849    783   PCSK7_RAT Proprotein convertase subtilisin/ke...2160.0002     48.1     27     45
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
193Q9V6K1    1441   TPP2_DROME Tripeptidyl-peptidase 2 OS=Drosoph...2110.0003     47.8     27     41GO:0005737; C:cytoplasm; NAS:FlyBase.::GO:0005615; C:extracellular space; IBA:RefGenome.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.::GO:0008240; F:tripeptidyl-peptidase activity; IDA:UniProtKB.
GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0006508; P:proteolysis; IDA:UniProtKB.
194P42781    976   XPR6_YARLI Dibasic-processing endoprotease OS...2570.0003     47.4     25     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
195Q16549    785   PCSK7_HUMAN Proprotein convertase subtilisin/...2160.0004     47.4     27     44GO:0030173; C:integral to Golgi membrane; IDA:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0016486; P:peptide hormone processing; NAS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
196Q59149    662   PRCA_NOSS1 Calcium-dependent protease OS=Nost...2720.0004     47.4     25     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
197Q28193    797   FURIN_BOVIN Furin OS=Bos taurus (Bovine). GN=...1930.0006     46.6     24     42GO:0005615; C:extracellular space; ISS:RefGenome.::GO:0005794; C:Golgi apparatus; ISS:RefGenome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
198P23916    662   PRCA_ANAVT Calcium-dependent protease OS=Anab...2720.001     45.4     25     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
199P29121    655   PCSK4_MOUSE Proprotein convertase subtilisin/...3150.001     45.4     23     38GO:0002080; C:acrosomal membrane; IDA:MGI.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0007340; P:acrosome reaction; IMP:MGI.::GO:0007339; P:binding of sperm to zona pellucida; IMP:MGI.::GO:0006508; P:proteolysis; IBA:RefGenome.::GO:0048240; P:sperm capacitation; IMP:MGI.
200Q78EH2    678   PCSK4_RAT Proprotein convertase subtilisin/ke...2580.002     44.7     24     40
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0006508; P:proteolysis; IBA:RefGenome.
201P23377    793   FURIN_RAT Furin OS=Rattus norvegicus (Rat). G...1550.002     44.7     27     44GO:0005789; C:endoplasmic reticulum membrane; IDA:RGD.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0031985; C:Golgi cisterna; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IMP:RGD.
GO:0007568; P:aging; IEP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
202P09958    794   FURIN_HUMAN Furin OS=Homo sapiens (Human). GN...1600.003     44.3     27     45GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0005796; C:Golgi lumen; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:BHF-UCL.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:MGI.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0048406; F:nerve growth factor binding; IDA:BHF-UCL.::GO:0042277; F:peptide binding; IDA:BHF-UCL.::GO:0002020; F:protease binding; IPI:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.::GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:BHF-UCL.
GO:0008283; P:cell proliferation; IMP:BHF-UCL.::GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.::GO:0032804; P:negative regulation of low-density lipoprotein particle receptor catabolic process; IDA:HGNC.::GO:0032911; P:negative regulation of transforming growth factor beta1 production; IMP:BHF-UCL.::GO:0032455; P:nerve growth factor processing; TAS:Reactome.::GO:0032902; P:nerve growth factor production; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IC:BHF-UCL.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006508; P:proteolysis; TAS:Reactome.::GO:0032940; P:secretion by cell; IDA:BHF-UCL.::GO:0006465; P:signal peptide processing; IDA:HGNC.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.::GO:0019067; P:viral assembly, maturation, egress, and release; IEP:BHF-UCL.
203P13134    814   KEX2_YEAST Kexin OS=Saccharomyces cerevisiae ...2520.004     44.3     26     39GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IDA:SGD.
GO:0007323; P:peptide pheromone maturation; IMP:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
204P30432    1679   FUR2_DROME Furin-like protease 2 OS=Drosophil...2620.005     43.9     25     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:FlyBase.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IDA:FlyBase.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro.
205P29119    783   FURI1_XENLA Furin-1 OS=Xenopus laevis (Africa...980.005     43.5     30     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
206P23188    793   FURIN_MOUSE Furin OS=Mus musculus (Mouse). GN...1610.012     42.4     26     44GO:0005769; C:early endosome; TAS:MGI.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0016021; C:integral to membrane; TAS:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0012510; C:trans-Golgi network transport vesicle membrane; TAS:MGI.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
207Q8NZ80    1150   C5AP_STRP8 C5a peptidase OS=Streptococcus pyo...960.013     42.4     33     54GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
208Q09175    709   KRP1_SCHPO Dibasic-processing endoprotease OS...2440.014     42.4     23     41GO:0009986; C:cell surface; NAS:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IDA:PomBase.
GO:0071432; P:peptide mating pheromone maturation involved in conjugation with cellular fusion; TAS:PomBase.::GO:0016485; P:protein processing; ISS:RefGenome.::GO:0006508; P:proteolysis; IGI:PomBase.
209O65351    757   SUBL_ARATH Subtilisin-like protease OS=Arabid...1478.1     33.1     29     40GO:0048046; C:apoplast; IDA:TAIR.::GO:0009505; C:plant-type cell wall; IDA:TAIR.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IDA:TAIR.
GO:0080001; P:mucilage extrusion from seed coat; IMP:TAIR.::GO:0048359; P:mucilage metabolic process involved seed coat development; IMP:TAIR.::GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
210O13359    938   KEX2_CANAW Kexin OS=Candida albicans (strain ...2520.015     42.4     27     41GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
211Q6UW60    755   PCSK4_HUMAN Proprotein convertase subtilisin/...1030.021     41.6     32     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
GO:0006508; P:proteolysis; IBA:RefGenome.
records
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