Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YEL037C
Length:
398
Number of sequences:
5887
Description:
YEL037C RAD23 SGDID:S000000763, Chr V from 82603-81407, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein with ubiquitin-like N terminus, subunit of Nuclear Excision Repair Factor 2 (NEF2) with Rad4p that binds damaged DNA; enhances protein deglycosylation activity of Png1p; also involved, with Rad4p, in ubiquitylated protein turnover"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P0CH28    690   UBC_BOVIN Polyubiquitin-C OS=Bos taurus (Bovi...621.5     34.7     29     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
122P62979    156   RS27A_HUMAN Ubiquitin-40S ribosomal protein S...581.3     33.9     31     57GO:0022627; C:cytosolic small ribosomal subunit; IDA:UniProtKB.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IDA:UniProtKB.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0006281; P:DNA repair; TAS:Reactome.::GO:0046788; P:egress of virus within host cell; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006414; P:translational elongation; TAS:Reactome.::GO:0006413; P:translational initiation; TAS:Reactome.::GO:0006415; P:translational termination; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0019083; P:viral transcription; TAS:Reactome.
123P62978    156   RS27A_CAVPO Ubiquitin-40S ribosomal protein S...581.3     33.9     31     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006412; P:translation; IEA:InterPro.
124P62992    156   RS27A_BOVIN Ubiquitin-40S ribosomal protein S...581.3     33.9     31     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006412; P:translation; IEA:InterPro.
125P79781    156   RS27A_CHICK Ubiquitin-40S ribosomal protein S...581.3     33.9     31     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005840; C:ribosome; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0035419; P:activation of MAPK activity involved in innate immune response; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0035681; P:toll-like receptor 15 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0035682; P:toll-like receptor 21 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.::GO:0034154; P:toll-like receptor 7 signaling pathway; TAS:Reactome.::GO:0006412; P:translation; IEA:InterPro.::GO:0019985; P:translesion synthesis; TAS:Reactome.
126P23324    229   UBIQP_EUPEU Polyubiquitin OS=Euplotes eurysto...571.4     34.3     32     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
127P0CG66    609   UBC_GORGO Polyubiquitin-C OS=Gorilla gorilla ...621.4     34.7     29     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
128P0CG48    685   UBC_HUMAN Polyubiquitin-C OS=Homo sapiens (Hu...621.5     34.7     29     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005515; F:protein binding; IPI:BHF-UCL.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0006281; P:DNA repair; TAS:Reactome.::GO:0046788; P:egress of virus within host cell; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
129P62976    658   UBIQP_CRIGR Polyubiquitin OS=Cricetulus grise...571.9     34.3     32     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
130P0CG61    761   UBC_PONPY Polyubiquitin-C OS=Pongo pygmaeus (...621.5     34.7     29     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
131P0CG64    761   UBC_PANTR Polyubiquitin-C OS=Pan troglodytes ...621.5     34.7     29     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
132P0CG69    763   UBIQP_DROME Polyubiquitin OS=Drosophila melan...621.5     34.7     29     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.
133Q71UE8    81   NEDD8_RAT NEDD8 OS=Rattus norvegicus (Rat). G...621.5     32.3     26     53GO:0005634; C:nucleus; IDA:RGD.
GO:0045116; P:protein neddylation; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.
134P29595    81   NEDD8_MOUSE NEDD8 OS=Mus musculus (Mouse). GN...621.5     32.3     26     53GO:0005634; C:nucleus; IDA:MGI.
GO:0008104; P:protein localization; IDA:MGI.::GO:0045116; P:protein neddylation; ISS:MGI.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
135Q9HGL0    137   YHLC_SCHPO Uncharacterized ubiquitin-like pro...471.7     33.1     40     60GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
136P0CG50    734   UBC_MOUSE Polyubiquitin-C OS=Mus musculus (Mo...571.9     34.7     32     58GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
137Q63429    810   UBC_RAT Polyubiquitin-C OS=Rattus norvegicus ...571.9     34.3     32     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:RGD.
138Q6P3R1    639   KIF22_XENTR Kinesin-like protein KIF22 OS=Xen...492     34.3     45     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007018; P:microtubule-based movement; IEA:InterPro.
139P42740    457   UBIQP_AGLNE Polyubiquitin OS=Aglaothamnion ne...538     32.3     34     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
140P21899    128   RL40_TRYBB Ubiquitin-60S ribosomal protein L4...532.5     32.3     28     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:UniProtKB-KW.
GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
141Q2HJA8    322   TMUB2_BOVIN Transmembrane and ubiquitin-like ...962.6     33.5     27     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
142Q9JK66    465   PRKN2_RAT E3 ubiquitin-protein ligase parkin ...952.7     33.9     26     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0008021; C:synaptic vesicle; IDA:RGD.
GO:0032403; F:protein complex binding; IDA:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0070997; P:neuron death; ISS:UniProtKB.::GO:0042551; P:neuron maturation; IEP:RGD.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0010506; P:regulation of autophagy; ISS:UniProtKB.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0006986; P:response to unfolded protein; IDA:RGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
143E1BY77    862   UBP13_CHICK Ubiquitin carboxyl-terminal hydro...732.9     33.9     33     52
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
144Q03919    77   RUB1_YEAST NEDD8-like protein RUB1 OS=Sacchar...672.9     31.2     25     54GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0031386; F:protein tag; IDA:SGD.
GO:0045116; P:protein neddylation; IDA:SGD.
145O50341    472   ATPB_FERIS ATP synthase subunit beta OS=Fervi...723     33.9     32     51GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.::GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IEA:InterPro.::GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
146P0CG82    381   UBIQP_TETPY Polyubiquitin OS=Tetrahymena pyri...623.1     33.5     29     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
147P19848    76   UBIQ_COPCO Ubiquitin OS=Coprinus congregatus ...573.1     31.2     30     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
148A4IH17    1129   BAG6_XENTR Large proline-rich protein bag6 OS...693.2     33.9     28     52GO:0071818; C:BAT3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0070628; F:proteasome binding; ISS:UniProtKB.::GO:0043022; F:ribosome binding; ISS:UniProtKB.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0007420; P:brain development; ISS:UniProtKB.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0018393; P:internal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.::GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
149Q5ZJI9    408   UBAC1_CHICK Ubiquitin-associated domain-conta...773.2     33.5     35     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
150Q08601    432   MCA1_YEAST Metacaspase-1 OS=Saccharomyces cer...483.4     33.5     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IDA:SGD.::GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IMP:SGD.
151A6ZP43    432   MCA1_YEAS7 Metacaspase-1 OS=Saccharomyces cer...483.4     33.5     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
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