UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YEL021W

Length:

267

Number of sequences:

5887

Description:

YEL021W URA3 SGDID:S000000747, Chr V from 116167-116970, Genome Release 64-1-1, Verified ORF, "Orotidine-5'-phosphate (OMP) decarboxylase, catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P03962	267	PYRF_YEAST Orotidine 5'-phosphate decarboxyla...	267	0	550	100	100	GO:0005829; C:cytosol; IDA:SGD.::GO:0005625; C:soluble fraction; IDA:SGD.
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IDA:SGD.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IMP:SGD.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
2	Q8J0E6	264	PYRF_TORDE Orotidine 5'-phosphate decarboxyla...	263	3e-167	470	84	94
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
3	Q9HFX0	265	PYRF_ZYGBA Orotidine 5'-phosphate decarboxyla...	263	5e-164	462	83	92
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
4	P33283	265	PYRF_CANGA Orotidine 5'-phosphate decarboxyla...	265	1e-163	461	82	91
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
5	P07922	267	PYRF_KLULA Orotidine 5'-phosphate decarboxyla...	262	3e-159	450	83	90
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
6	P41769	267	PYRF_KLUMA Orotidine 5'-phosphate decarboxyla...	265	3e-159	450	82	89
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
7	Q9Y726	268	PYRF_SACEX Orotidine 5'-phosphate decarboxyla...	263	1e-155	441	80	88
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
8	Q757S1	267	PYRF_ASHGO Orotidine 5'-phosphate decarboxyla...	267	9e-153	434	76	88
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
9	P78724	267	PYRF_HANAN Orotidine 5'-phosphate decarboxyla...	261	3e-150	427	76	87
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
10	P79075	265	PYRF_CYBFA Orotidine 5'-phosphate decarboxyla...	259	2e-147	420	75	87
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
11	Q06375	263	PYRF_PICAN Orotidine 5'-phosphate decarboxyla...	258	1e-146	418	75	88
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
12	Q6BY69	267	PYRF_DEBHA Orotidine 5'-phosphate decarboxyla...	260	6e-146	417	73	87
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
13	Q01378	270	PYRF_CANBO Orotidine 5'-phosphate decarboxyla...	260	2e-145	416	74	87
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
14	O42771	268	PYRF_CANTR Orotidine 5'-phosphate decarboxyla...	265	3e-145	415	72	86
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
15	P48844	261	PYRF_KODOH Orotidine 5'-phosphate decarboxyla...	258	7e-145	414	74	88
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
16	P32430	266	PYRF_CANMA Orotidine 5'-phosphate decarboxyla...	265	8e-145	414	72	86
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
17	P49434	267	PYRF_PICST Orotidine 5'-phosphate decarboxyla...	261	2e-144	413	72	87
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
18	O94127	266	PYRF_CYBJA Orotidine 5'-phosphate decarboxyla...	262	1e-143	410	74	87
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
19	O93864	268	PYRF_PACTA Orotidine 5'-phosphate decarboxyla...	262	6e-143	409	73	85
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
20	Q6IUR4	262	PYRF_CANGY Orotidine 5'-phosphate decarboxyla...	259	4e-142	407	72	88
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
21	P13649	270	PYRF_CANAL Orotidine 5'-phosphate decarboxyla...	267	1e-141	406	71	84
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IMP:CGD.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.::GO:0044406; P:adhesion to host; IMP:CGD.::GO:0030447; P:filamentous growth; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0046109; P:uridine biosynthetic process; IMP:CGD.
22	Q9HFN9	265	PYRF_CANRU Orotidine 5'-phosphate decarboxyla...	263	3e-141	405	73	84
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
23	Q9C150	270	PYRF_CANDC Orotidine 5'-phosphate decarboxyla...	267	2e-140	402	70	84
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
24	Q12595	268	PYRF_CANPA Orotidine 5'-phosphate decarboxyla...	263	6e-137	394	69	84
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
25	Q9UVZ5	265	PYRF_SACFI Orotidine 5'-phosphate decarboxyla...	263	1e-133	385	69	83
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
26	Q9C1J2	263	PYRF_PICPA Orotidine 5'-phosphate decarboxyla...	255	7e-133	383	74	85
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
27	Q12724	286	PYRF_YARLI Orotidine 5'-phosphate decarboxyla...	283	3e-116	342	60	73
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
28	Q12604	284	PYRF_DIPMG Orotidine 5'-phosphate decarboxyla...	274	1e-112	332	61	73
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
29	P14964	278	PYRF_SCHCO Orotidine 5'-phosphate decarboxyla...	273	9e-89	271	52	68
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
30	P15188	283	PYRF_USTMA Orotidine 5'-phosphate decarboxyla...	280	1e-87	269	50	66
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
31	Q7Z8L4	276	PYRF_PENCA Orotidine 5'-phosphate decarboxyla...	275	1e-87	268	50	67
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.

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