UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YEL021W

Length:

267

Number of sequences:

5887

Description:

YEL021W URA3 SGDID:S000000747, Chr V from 116167-116970, Genome Release 64-1-1, Verified ORF, "Orotidine-5'-phosphate (OMP) decarboxylase, catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
91	A9M3Q3	246	PYRF_NEIM0 Orotidine 5'-phosphate decarboxyla...	250	0.003	41.6	23	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
92	Q4ZVD9	232	PYRF_PSEU2 Orotidine 5'-phosphate decarboxyla...	125	0.003	41.6	28	47
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
93	A5F6Y1	231	PYRF_VIBC3 Orotidine 5'-phosphate decarboxyla...	216	0.004	41.2	26	44
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
94	Q884R0	232	PYRF_PSESM Orotidine 5'-phosphate decarboxyla...	125	0.006	40.8	28	48
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
95	A3M508	232	PYRF_ACIBT Orotidine 5'-phosphate decarboxyla...	101	0.007	40.4	31	49
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
96	B2HZE8	232	PYRF_ACIBC Orotidine 5'-phosphate decarboxyla...	101	0.007	40.4	31	49
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
97	B7I534	232	PYRF_ACIB5 Orotidine 5'-phosphate decarboxyla...	101	0.007	40.4	31	49
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
98	Q3J8N5	232	PYRF_NITOC Orotidine 5'-phosphate decarboxyla...	227	0.007	40.4	22	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
99	A6V3L5	232	PYRF_PSEA7 Orotidine 5'-phosphate decarboxyla...	233	0.008	40.4	23	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
100	O58462	208	PYRF_PYRHO Orotidine 5'-phosphate decarboxyla...	212	0.008	40	24	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
101	A7MUN7	233	PYRF_VIBHB Orotidine 5'-phosphate decarboxyla...	230	0.008	40.4	23	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
102	A5UBN7	230	PYRF_HAEIE Orotidine 5'-phosphate decarboxyla...	243	0.01	40	23	39
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
103	Q21IS8	238	PYRF_SACD2 Orotidine 5'-phosphate decarboxyla...	220	0.011	40	25	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
104	B4EW04	248	PYRF_PROMH Orotidine 5'-phosphate decarboxyla...	237	0.012	40	22	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
105	Q15T09	231	PYRF_PSEA6 Orotidine 5'-phosphate decarboxyla...	220	0.012	39.7	22	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
106	A1KT74	246	PYRF_NEIMF Orotidine 5'-phosphate decarboxyla...	253	0.012	40	23	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
107	Q9K005	246	PYRF_NEIMB Orotidine 5'-phosphate decarboxyla...	253	0.012	40	23	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
108	A8FVN0	234	PYRF_SHESH Orotidine 5'-phosphate decarboxyla...	223	0.014	39.7	25	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
109	C3LNL5	231	PYRF_VIBCM Orotidine 5'-phosphate decarboxyla...	219	0.014	39.7	25	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
110	Q9KQT7	231	PYRF_VIBCH Orotidine 5'-phosphate decarboxyla...	219	0.014	39.7	25	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
111	B0BP16	230	PYRF_ACTPJ Orotidine 5'-phosphate decarboxyla...	223	0.016	39.3	23	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
112	B3GXH2	230	PYRF_ACTP7 Orotidine 5'-phosphate decarboxyla...	223	0.016	39.3	23	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
113	A3N0A0	230	PYRF_ACTP2 Orotidine 5'-phosphate decarboxyla...	223	0.016	39.3	23	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
114	P43812	230	PYRF_HAEIN Orotidine 5'-phosphate decarboxyla...	234	0.016	39.3	23	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
115	Q9UZ35	208	PYRF_PYRAB Orotidine 5'-phosphate decarboxyla...	221	0.018	39.3	23	40
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:HAMAP.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
116	Q7NTL2	247	PYRF_CHRVO Orotidine 5'-phosphate decarboxyla...	218	0.021	39.3	24	40
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
117	B8F472	230	PYRF_HAEPS Orotidine 5'-phosphate decarboxyla...	225	0.022	38.9	23	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
118	Q1LTG7	249	PYRF_BAUCH Orotidine 5'-phosphate decarboxyla...	233	0.023	38.9	23	40
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
119	Q87N49	233	PYRF_VIBPA Orotidine 5'-phosphate decarboxyla...	219	0.025	38.9	24	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
120	Q4QJV1	230	PYRF_HAEI8 Orotidine 5'-phosphate decarboxyla...	243	0.027	38.9	23	39
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
121	C1CD54	233	PYRF_STRZJ Orotidine 5'-phosphate decarboxyla...	167	0.027	38.9	28	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.

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