UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YEL021W

Length:

267

Number of sequences:

5887

Description:

YEL021W URA3 SGDID:S000000747, Chr V from 116167-116970, Genome Release 64-1-1, Verified ORF, "Orotidine-5'-phosphate (OMP) decarboxylase, catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	P78748	396	PYRF_SORMK Orotidine 5'-phosphate decarboxyla...	226	5e-22	97.4	31	47
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
62	P05035	397	PYRF_NEUCR Orotidine 5'-phosphate decarboxyla...	144	1e-20	93.6	38	55
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
63	P14017	376	PYRF_CEPAC Orotidine 5'-phosphate decarboxyla...	127	2e-23	101	42	61
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
64	P21594	381	PYRF_HYPJE Orotidine 5'-phosphate decarboxyla...	130	4e-21	94.7	42	57
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
65	Q12709	379	PYRF_HYPAT Orotidine 5'-phosphate decarboxyla...	130	1e-23	102	44	59
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
66	Q5WWS3	229	PYRF_LEGPL Orotidine 5'-phosphate decarboxyla...	217	0.00002	48.5	25	44
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
67	B5FG54	234	PYRF_VIBFM Orotidine 5'-phosphate decarboxyla...	235	0.00007	46.6	26	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
68	Q5E3Z6	234	PYRF_VIBF1 Orotidine 5'-phosphate decarboxyla...	235	0.00007	46.6	26	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
69	Q5ZVL5	229	PYRF_LEGPH Orotidine 5'-phosphate decarboxyla...	217	0.00007	46.6	24	46
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
70	Q8U1U1	211	PYRF_PYRFU Orotidine 5'-phosphate decarboxyla...	225	0.00008	46.2	26	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
71	Q59654	232	PYRF_PSEAE Orotidine 5'-phosphate decarboxyla...	231	0.00008	46.2	24	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
72	Q02P38	232	PYRF_PSEAB Orotidine 5'-phosphate decarboxyla...	231	0.00008	46.2	24	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
73	B7V800	232	PYRF_PSEA8 Orotidine 5'-phosphate decarboxyla...	231	0.00008	46.2	24	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
74	Q2SCG0	233	PYRF_HAHCH Orotidine 5'-phosphate decarboxyla...	221	0.00009	46.2	26	40
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
75	A5IBR7	229	PYRF_LEGPC Orotidine 5'-phosphate decarboxyla...	217	0.0001	45.8	25	44
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
76	Q8EEI4	231	PYRF_SHEON Orotidine 5'-phosphate decarboxyla...	218	0.0001	45.8	24	44
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
77	Q65SI1	234	PYRF_MANSM Orotidine 5'-phosphate decarboxyla...	241	0.0002	45.4	24	39
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
78	A6W097	235	PYRF_MARMS Orotidine 5'-phosphate decarboxyla...	228	0.0002	45.1	26	46
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
79	Q9CMM1	233	PYRF_PASMU Orotidine 5'-phosphate decarboxyla...	243	0.0002	45.1	25	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
80	Q5X5E0	229	PYRF_LEGPA Orotidine 5'-phosphate decarboxyla...	217	0.0003	44.7	24	44
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
81	C3K758	232	PYRF_PSEFS Orotidine 5'-phosphate decarboxyla...	243	0.0004	44.3	24	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
82	Q970X0	213	PYRF_SULTO Orotidine 5'-phosphate decarboxyla...	163	0.0004	43.9	28	48
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
83	Q4KFV3	233	PYRF_PSEF5 Orotidine 5'-phosphate decarboxyla...	237	0.0006	43.9	24	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
84	A1SYZ6	234	PYRF_PSYIN Orotidine 5'-phosphate decarboxyla...	219	0.0006	43.9	26	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
85	B6EIY4	234	PYRF_ALISL Orotidine 5'-phosphate decarboxyla...	223	0.0007	43.5	27	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
86	A6VPK5	232	PYRF_ACTSZ Orotidine 5'-phosphate decarboxyla...	243	0.0008	43.5	23	40
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
87	C5BSJ7	232	PYRF_TERTT Orotidine 5'-phosphate decarboxyla...	225	0.001	43.1	24	40
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
88	Q3K8H1	232	PYRF_PSEPF Orotidine 5'-phosphate decarboxyla...	243	0.001	42.7	23	40
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
89	Q8D2J1	232	PYRF_WIGBR Orotidine 5'-phosphate decarboxyla...	226	0.001	42.7	20	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
90	A1TZF4	236	PYRF_MARAV Orotidine 5'-phosphate decarboxyla...	219	0.002	42.4	25	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
91	A9M3Q3	246	PYRF_NEIM0 Orotidine 5'-phosphate decarboxyla...	250	0.003	41.6	23	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.

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