UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YEL021W

Length:

267

Number of sequences:

5887

Description:

YEL021W URA3 SGDID:S000000747, Chr V from 116167-116970, Genome Release 64-1-1, Verified ORF, "Orotidine-5'-phosphate (OMP) decarboxylase, catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
181	B8D963	236	PYRF_BUCA5 Orotidine 5'-phosphate decarboxyla...	209	0.73	34.3	23	39
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
182	Q2Y7B1	239	PYRF_NITMU Orotidine 5'-phosphate decarboxyla...	225	0.82	34.3	23	39
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
183	Q92G23	414	HEM1_RICCN 5-aminolevulinate synthase OS=Rick...	59	0.84	34.7	37	56
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
184	Q4UJV4	414	HEM1_RICFE 5-aminolevulinate synthase OS=Rick...	59	0.87	34.7	37	56
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
185	Q8RG83	237	PYRF_FUSNN Orotidine 5'-phosphate decarboxyla...	183	0.95	33.9	26	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
186	Q043A6	235	PYRF_LACGA Orotidine 5'-phosphate decarboxyla...	224	0.99	33.9	26	44
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
187	Q32GQ2	245	PYRF_SHIDS Orotidine 5'-phosphate decarboxyla...	219	1	33.9	23	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
188	A4WAY2	246	PYRF_ENT38 Orotidine 5'-phosphate decarboxyla...	219	1.1	33.9	21	44
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
189	B1LH07	245	PYRF_ECOSM Orotidine 5'-phosphate decarboxyla...	218	1.1	33.9	23	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
190	B7N497	245	PYRF_ECOLU Orotidine 5'-phosphate decarboxyla...	218	1.1	33.9	23	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
191	B7NVQ5	245	PYRF_ECO7I Orotidine 5'-phosphate decarboxyla...	218	1.1	33.9	23	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
192	P58640	245	PYRF_ECO57 Orotidine 5'-phosphate decarboxyla...	218	1.1	33.9	23	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
193	Q1RIV2	414	HEM1_RICBR 5-aminolevulinate synthase OS=Rick...	60	1.2	34.3	37	55
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
194	Q4FRL9	232	PYRF_PSYA2 Orotidine 5'-phosphate decarboxyla...	215	1.2	33.5	25	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
195	B0TDZ7	243	PYRF_HELMI Orotidine 5'-phosphate decarboxyla...	75	1.4	33.5	32	44
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
196	Q8EUY3	231	PYRF_MYCPE Orotidine 5'-phosphate decarboxyla...	165	1.5	33.5	26	43
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
197	O74110	214	PYRF_THEAC Orotidine 5'-phosphate decarboxyla...	216	1.6	33.1	23	46
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
198	B2U0H4	245	PYRF_SHIB3 Orotidine 5'-phosphate decarboxyla...	219	2	33.1	23	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
199	Q9PIC1	279	PYRF_CAMJE Orotidine 5'-phosphate decarboxyla...	217	2.2	33.1	23	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
200	Q3IGA7	234	PYRF_PSEHT Orotidine 5'-phosphate decarboxyla...	229	2.4	32.7	27	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
201	Q1RC84	245	PYRF_ECOUT Orotidine 5'-phosphate decarboxyla...	219	2.6	32.7	23	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
202	B7MLV7	245	PYRF_ECO45 Orotidine 5'-phosphate decarboxyla...	219	2.6	32.7	23	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
203	Q39VY5	239	PYRF_GEOMG Orotidine 5'-phosphate decarboxyla...	170	2.9	32.7	27	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
204	Q8TS37	221	PYRF_METAC Orotidine 5'-phosphate decarboxyla...	224	3.2	32.3	24	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
205	B9LZK2	239	PYRF_GEOSF Orotidine 5'-phosphate decarboxyla...	229	3.4	32.3	23	41
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
206	O29333	209	PYRF_ARCFU Orotidine 5'-phosphate decarboxyla...	233	3.5	32.3	25	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
207	C6DK13	247	PYRF_PECCP Orotidine 5'-phosphate decarboxyla...	81	4.7	32	30	49
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
208	Q6F9Z3	227	PYRF_ACIAD Orotidine 5'-phosphate decarboxyla...	95	4.7	32	27	46
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
209	B1HQC3	234	PYRF_LYSSC Orotidine 5'-phosphate decarboxyla...	193	5.3	31.6	27	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
210	A1VYA1	226	PYRF_CAMJJ Orotidine 5'-phosphate decarboxyla...	227	5.8	31.6	22	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.
211	A8FKG8	226	PYRF_CAMJ8 Orotidine 5'-phosphate decarboxyla...	227	5.8	31.6	22	42
									GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC.
									GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro.

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