Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YEL012W
Length:
218
Number of sequences:
5887
Description:
YEL012W UBC8 SGDID:S000000738, Chr V from 131772-131776,131900-132551, Genome Release 64-1-1, Verified ORF, "Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q75AF2    184   UBC12_ASHGO NEDD8-conjugating enzyme UBC12 OS...1049e-18     82     42     60
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
122Q9D1C1    179   UBE2C_MOUSE Ubiquitin-conjugating enzyme E2 C...1481e-17     81.6     32     56GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0010994; P:free ubiquitin chain polymerization; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
123O13685    148   UBC13_SCHPO Ubiquitin-conjugating enzyme E2 1...1221e-17     80.5     35     53GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0071479; P:cellular response to ionizing radiation; IDA:PomBase.::GO:0006301; P:postreplication repair; IMP:PomBase.::GO:0070534; P:protein K63-linked ubiquitination; IDA:PomBase.
124Q9UTN8    155   UBC14_SCHPO Ubiquitin-conjugating enzyme E2 1...1392e-17     80.5     29     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.
125Q08BH7    194   UBE2T_DANRE Ubiquitin-conjugating enzyme E2 T...1242e-17     80.9     36     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.
126P52482    193   UB2E1_MOUSE Ubiquitin-conjugating enzyme E2 E...1514e-17     80.1     30     53GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
127P51965    193   UB2E1_HUMAN Ubiquitin-conjugating enzyme E2 E...1516e-17     79.7     30     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042296; F:ISG15 ligase activity; IDA:HGNC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.::GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
128Q6FVQ8    187   UBC12_CANGA NEDD8-conjugating enzyme UBC12 OS...1346e-17     79.7     38     58
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
129Q8L7T3    180   UBC20_ARATH Ubiquitin-conjugating enzyme E2 2...902e-16     78.2     44     61
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0008283; P:cell proliferation; IEP:TAIR.
130Q9SDY5    184   RCE1_ARATH NEDD8-conjugating enzyme Ubc12 OS=...1432e-16     78.2     31     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019788; F:NEDD8 ligase activity; TAS:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009733; P:response to auxin stimulus; IMP:TAIR.
131P52485    232   UBCD2_DROME Ubiquitin-conjugating enzyme E2-2...1513e-16     78.2     30     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:FlyBase.
GO:0019915; P:lipid storage; IDA:FlyBase.
132O74549    177   UBC12_SCHPO NEDD8-conjugating enzyme ubc12 OS...1445e-16     76.6     31     56GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019788; F:NEDD8 ligase activity; IC:PomBase.
GO:0045116; P:protein neddylation; ISS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.
133Q5R5I4    154   UB2L3_PONAB Ubiquitin-conjugating enzyme E2 L...1536e-16     76.3     28     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0071385; P:cellular response to glucocorticoid stimulus; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
134Q5UQ40    1297   UBC4_MIMIV Probable bifunctional E2/E3 enzyme...1546e-16     80.9     30     57GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
135Q4V908    221   UBE2S_DANRE Ubiquitin-conjugating enzyme E2 S...1617e-16     77     29     45GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0010994; P:free ubiquitin chain polymerization; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
136P68037    154   UB2L3_MOUSE Ubiquitin-conjugating enzyme E2 L...1167e-16     75.9     33     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0071385; P:cellular response to glucocorticoid stimulus; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
137P68036    154   UB2L3_HUMAN Ubiquitin-conjugating enzyme E2 L...1167e-16     75.9     33     53GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0071385; P:cellular response to glucocorticoid stimulus; IDA:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:UniProtKB.
138Q3MHP1    154   UB2L3_BOVIN Ubiquitin-conjugating enzyme E2 L...1167e-16     75.9     33     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0071385; P:cellular response to glucocorticoid stimulus; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
139O60015    188   UBCX_PICAN Ubiquitin-conjugating enzyme E2-21...1850.000000000000001     75.9     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007031; P:peroxisome organization; IEA:UniProtKB-KW.
140Q9VSF3    181   UBC12_DROME NEDD8-conjugating enzyme Ubc12 OS...1520.000000000000001     75.5     27     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019788; F:NEDD8 ligase activity; ISS:UniProtKB.::GO:0018169; F:ribosomal S6-glutamic acid ligase activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:FlyBase.::GO:0045116; P:protein neddylation; ISS:UniProtKB.
141Q54TI6    230   UBC12_DICDI NEDD8-conjugating enzyme Ubc12 OS...1070.000000000000002     75.9     30     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019788; F:NEDD8 ligase activity; ISS:dictyBase.::GO:0018169; F:ribosomal S6-glutamic acid ligase activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0045116; P:protein neddylation; ISS:dictyBase.
142Q9LJD7    182   COP10_ARATH Constitutive photomorphogenesis p...1500.000000000000002     75.1     27     54GO:0005634; C:nucleus; IDA:TAIR.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.::GO:0010099; P:regulation of photomorphogenesis; IMP:TAIR.
143B3MQV3    209   UBE2S_DROAN Ubiquitin-conjugating enzyme E2 S...1450.000000000000002     75.5     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.
144Q5UQC9    158   UBC1_MIMIV Probable ubiquitin-conjugating enz...1530.000000000000002     74.7     33     61
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
145Q7ZY08    192   UBE2T_XENLA Ubiquitin-conjugating enzyme E2 T...1230.000000000000002     75.1     32     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.
146Q9C8X7    154   UBC31_ARATH Probable ubiquitin-conjugating en...1210.000000000000003     74.3     32     58GO:0005773; C:vacuole; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
147Q6IRC7    185   UBE2F_XENLA NEDD8-conjugating enzyme UBE2F OS...1280.000000000000003     74.3     34     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019788; F:NEDD8 ligase activity; ISS:UniProtKB.
GO:0045116; P:protein neddylation; ISS:UniProtKB.
148P29340    183   UBCX_YEAST Ubiquitin-conjugating enzyme E2-21...1090.000000000000005     73.9     36     60GO:0005777; C:peroxisome; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.
GO:0051865; P:protein autoubiquitination; IDA:SGD.::GO:0016562; P:protein import into peroxisome matrix, receptor recycling; IMP:SGD.::GO:0006513; P:protein monoubiquitination; IDA:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.
149B3NWW9    209   UBE2S_DROER Ubiquitin-conjugating enzyme E2 S...1450.000000000000005     74.3     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.
150Q5M8Y2    185   UBE2F_XENTR NEDD8-conjugating enzyme UBE2F OS...1280.000000000000007     73.6     34     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019788; F:NEDD8 ligase activity; ISS:UniProtKB.
GO:0045116; P:protein neddylation; ISS:UniProtKB.
151B4Q2J2    209   UBE2S_DROYA Ubiquitin-conjugating enzyme E2 S...1450.000000000000008     73.9     32     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.
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