Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YEL012W
Length:
218
Number of sequences:
5887
Description:
YEL012W UBC8 SGDID:S000000738, Chr V from 131772-131776,131900-132551, Genome Release 64-1-1, Verified ORF, "Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P28263    218   UBC8_YEAST Ubiquitin-conjugating enzyme E2-24...2181e-156     439     100     100GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
GO:0045721; P:negative regulation of gluconeogenesis; IMP:SGD.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.
2Q9P7R4    184   UBC8_SCHPO Ubiquitin-conjugating enzyme E2 8 ...1502e-72     224     66     82GO:0005737; C:cytoplasm; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.
3P42749    185   UBC5_ARATH Ubiquitin-conjugating enzyme E2 5 ...1753e-68     214     55     74GO:0005829; C:cytosol; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
4P42748    187   UBC4_ARATH Ubiquitin-conjugating enzyme E2 4 ...1471e-66     209     62     81
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
5P16577    184   UBC4_WHEAT Ubiquitin-conjugating enzyme E2-23...1473e-65     206     63     79
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
6P42750    183   UBC6_ARATH Ubiquitin-conjugating enzyme E2 6 ...1517e-64     202     59     79
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
7P62257    183   UBE2H_MOUSE Ubiquitin-conjugating enzyme E2 H...1534e-60     192     59     76
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
8P62256    183   UBE2H_HUMAN Ubiquitin-conjugating enzyme E2 H...1534e-60     192     59     76
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
9Q32LN1    183   UBE2H_BOVIN Ubiquitin-conjugating enzyme E2 H...1534e-60     192     59     76
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
10P52478    192   UBC1_CAEEL Ubiquitin-conjugating enzyme E2 1 ...1482e-26     105     35     61
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:WormBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.
GO:0006281; P:DNA repair; IDA:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
11P63149    152   UBE2B_RAT Ubiquitin-conjugating enzyme E2 B O...1495e-26     103     36     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; IEP:RGD.
12P63148    152   UBE2B_RABIT Ubiquitin-conjugating enzyme E2 B...1495e-26     103     36     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
13P63147    152   UBE2B_MOUSE Ubiquitin-conjugating enzyme E2 B...1495e-26     103     36     61GO:0000790; C:nuclear chromatin; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001741; C:XY body; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0051026; P:chiasma assembly; IMP:MGI.::GO:0070076; P:histone lysine demethylation; IMP:MGI.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0006344; P:maintenance of chromatin silencing; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0033128; P:negative regulation of histone phosphorylation; IMP:MGI.::GO:0010845; P:positive regulation of reciprocal meiotic recombination; IMP:MGI.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0007288; P:sperm axoneme assembly; IMP:MGI.::GO:0070193; P:synaptonemal complex organization; IMP:MGI.
14P63146    152   UBE2B_HUMAN Ubiquitin-conjugating enzyme E2 B...1495e-26     103     36     61GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005657; C:replication fork; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; IMP:UniProtKB.::GO:0043951; P:negative regulation of cAMP-mediated signaling; IDA:UniProtKB.::GO:0006301; P:postreplication repair; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0006513; P:protein monoubiquitination; IMP:UniProtKB.::GO:0050821; P:protein stabilization; IMP:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0009411; P:response to UV; IGI:UniProtKB.
15Q32P99    152   UBE2B_BOVIN Ubiquitin-conjugating enzyme E2 B...1495e-26     103     36     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
16Q96UP5    151   UBC2_EMENI Ubiquitin-conjugating enzyme E2 2 ...1491e-25     102     34     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17P78717    151   UBC2_NECHA Ubiquitin-conjugating enzyme E2 2 ...1491e-25     102     33     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q94490    148   UBCB_DICDI Ubiquitin conjugating enzyme E2 B ...1491e-25     102     34     60
GO:0004842; F:ubiquitin-protein ligase activity; ISS:dictyBase.
GO:0009653; P:anatomical structure morphogenesis; IMP:dictyBase.
19Q9Z255    152   UBE2A_MOUSE Ubiquitin-conjugating enzyme E2 A...1491e-25     102     36     60GO:0000790; C:nuclear chromatin; IDA:MGI.::GO:0001741; C:XY body; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0060135; P:maternal process involved in female pregnancy; IMP:MGI.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
20P49459    152   UBE2A_HUMAN Ubiquitin-conjugating enzyme E2 A...1491e-25     102     36     60GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.::GO:0033522; P:histone H2A ubiquitination; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0006301; P:postreplication repair; NAS:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0009411; P:response to UV; IGI:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
21Q4WLA7    151   UBC2_ASPFU Ubiquitin-conjugating enzyme E2 2 ...1491e-25     102     34     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22P0CS16    169   UBC2_CRYNJ Ubiquitin-conjugating enzyme E2 2 ...1472e-25     102     36     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23P0CS17    169   UBC2_CRYNB Ubiquitin-conjugating enzyme E2 2 ...1472e-25     102     36     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24P25153    151   UBCD6_DROME Ubiquitin-conjugating enzyme E2-1...1492e-25     102     35     59GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; IPI:BHF-UCL.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IC:BHF-UCL.
GO:0051299; P:centrosome separation; IMP:FlyBase.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:BHF-UCL.::GO:0006281; P:DNA repair; IGI:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IMP:BHF-UCL.::GO:2000499; P:negative regulation of induction of apoptosis in response to chemical stimulus; IMP:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.
25P15732    148   UBC5_YEAST Ubiquitin-conjugating enzyme E2-16...1503e-25     101     37     55GO:0000502; C:proteasome complex; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
GO:0000209; P:protein polyubiquitination; IDA:SGD.::GO:0006950; P:response to stress; IDA:SGD.
26P52490    153   UBC13_YEAST Ubiquitin-conjugating enzyme E2 1...1535e-25     100     37     59GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0031371; C:ubiquitin conjugating enzyme complex; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0010994; P:free ubiquitin chain polymerization; IDA:SGD.::GO:0006301; P:postreplication repair; IMP:SGD.::GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; IDA:SGD.
27P35128    151   UBE2N_DROME Ubiquitin-conjugating enzyme E2 N...1547e-25     100     38     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0007412; P:axon target recognition; IMP:FlyBase.::GO:0007629; P:flight behavior; IMP:FlyBase.::GO:0007625; P:grooming behavior; IMP:FlyBase.::GO:0007630; P:jump response; IMP:FlyBase.::GO:0008594; P:photoreceptor cell morphogenesis; IMP:FlyBase.::GO:0072347; P:response to anesthetic; IMP:FlyBase.
28P25867    147   UBCD1_DROME Ubiquitin-conjugating enzyme E2-1...1238e-25     100     40     60GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IGI:FlyBase.
GO:0051276; P:chromosome organization; IMP:FlyBase.::GO:0001751; P:compound eye photoreceptor cell differentiation; IMP:FlyBase.::GO:0008054; P:cyclin catabolic process; IMP:FlyBase.::GO:0048132; P:female germ-line stem cell division; IMP:FlyBase.::GO:0030718; P:germ-line stem cell maintenance; IMP:FlyBase.::GO:0007140; P:male meiosis; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0016322; P:neuron remodeling; IDA:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase.::GO:0045676; P:regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007286; P:spermatid development; IMP:FlyBase.
29P25866    152   UBC2_WHEAT Ubiquitin-conjugating enzyme E2 2 ...1178e-25     100     39     67
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
30P62840    147   UB2D2_XENLA Ubiquitin-conjugating enzyme E2 D...1239e-25     100     40     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
31P62839    147   UB2D2_RAT Ubiquitin-conjugating enzyme E2 D2 ...1239e-25     100     40     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
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