Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR545W
Length:
1796
Number of sequences:
5887
Description:
YDR545W YRF1-1 SGDID:S000002953, Chr IV from 1526321-1531711, Genome Release 64-1-1, Verified ORF, "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301P17844    614   DDX5_HUMAN Probable ATP-dependent RNA helicas...1120.41     39.3     31     46GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0050681; F:androgen receptor binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.::GO:0036002; F:pre-mRNA binding; IDA:UniProtKB.::GO:0003724; F:RNA helicase activity; IMP:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
GO:0016049; P:cell growth; NAS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IMP:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:2001014; P:regulation of skeletal muscle cell differentiation; ISS:UniProtKB.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
302Q10MH8    770   RH24_ORYSJ DEAD-box ATP-dependent RNA helicas...1370.41     39.3     23     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
303Q8DHC6    668   UVRB_THEEB UvrABC system protein B OS=Thermos...970.42     39.3     28     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:InterPro.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
304Q5UQD1    524   YR458_MIMIV Putative ATP-dependent RNA helica...1080.43     38.9     28     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
305Q3EBC8    1388   DCL2_ARATH Endoribonuclease Dicer homolog 2 O...1030.45     39.3     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.
GO:0051607; P:defense response to virus; IMP:TAIR.::GO:0010216; P:maintenance of DNA methylation; IMP:TAIR.::GO:0010267; P:production of ta-siRNAs involved in RNA interference; IMP:TAIR.
306Q31ES7    678   UVRB_THICR UvrABC system protein B OS=Thiomic...1050.48     38.9     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
307P22596    485   GC_EHV4 Glycoprotein C OS=virus). GN=GC Synon...950.5     38.9     34     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.
308P35837    233   VG26_BPP22 Tail needle protein gp26 OS=Entero...1390.7     37.4     24     41GO:0019012; C:virion; IEA:UniProtKB-SubCell.
309Q8RXK6    505   RH8_ARATH DEAD-box ATP-dependent RNA helicase...1310.53     38.5     27     47GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0019048; P:virus-host interaction; IPI:TAIR.
310Q55681    831   RECG_SYNY3 ATP-dependent DNA helicase recG OS...1320.53     38.9     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
311P0CQ96    442   SUB2_CRYNJ ATP-dependent RNA helicase SUB2 OS...1290.54     38.5     26     48GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
312P0CQ97    442   SUB2_CRYNB ATP-dependent RNA helicase SUB2 OS...1290.54     38.5     26     48GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
313B0UUZ9    419   RHLB_HAES2 ATP-dependent RNA helicase rhlB OS...1430.56     38.5     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
314Q65N62    487   CSHA_BACLD DEAD-box ATP-dependent RNA helicas...1070.57     38.5     29     46GO:0043590; C:bacterial nucleoid; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; ISS:UniProtKB.
315Q68XG5    662   UVRB_RICTY UvrABC system protein B OS=Rickett...1190.58     38.5     24     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:InterPro.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
316Q6CIV2    554   DBP2_KLULA ATP-dependent RNA helicase DBP2 OS...920.59     38.5     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
317Q91Z22    195   PORIM_MOUSE Porimin OS=Mus musculus (Mouse). ...1430.59     37.4     26     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
318P53166    561   MRH4_YEAST ATP-dependent RNA helicase MRH4, m...660.59     38.5     33     58GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003724; F:RNA helicase activity; IDA:SGD.
GO:0042254; P:ribosome biogenesis; TAS:SGD.
319A6ZUB2    561   MRH4_YEAS7 ATP-dependent RNA helicase MRH4, m...660.59     38.5     33     58GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
320B0CE09    668   UVRB_ACAM1 UvrABC system protein B OS=Acaryoc...1310.59     38.5     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
321Q46IE1    678   UVRB_PROMT UvrABC system protein B OS=Prochlo...1100.6     38.5     27     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:InterPro.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
322Q5RC67    820   DDX23_PONAB Probable ATP-dependent RNA helica...1100.6     38.5     28     45GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
323A5E3W5    433   SUB2_LODEL ATP-dependent RNA helicase SUB2 OS...1310.61     38.5     26     50GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
324A2C5B3    678   UVRB_PROM1 UvrABC system protein B OS=Prochlo...1100.62     38.5     27     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0009381; F:excinuclease ABC activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
325Q9M2E0    498   RH12_ARATH DEAD-box ATP-dependent RNA helicas...970.62     38.5     30     49GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
326P39517    506   DHH1_YEAST ATP-dependent RNA helicase DHH1 OS...920.65     38.5     30     50GO:0000932; C:cytoplasmic mRNA processing body; IDA:SGD.::GO:0010494; C:cytoplasmic stress granule; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000753; P:cell morphogenesis involved in conjugation with cellular fusion; IMP:SGD.::GO:0033962; P:cytoplasmic mRNA processing body assembly; IMP:SGD.::GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IMP:SGD.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0034063; P:stress granule assembly; IMP:SGD.
327A6ZXG9    506   DHH1_YEAS7 ATP-dependent RNA helicase DHH1 OS...920.65     38.5     30     50GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
328P31996    326   CD68_MOUSE Macrosialin OS=Mus musculus (Mouse...770.66     38.1     34     57GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0071310; P:cellular response to organic substance; IDA:MGI.
329Q9BUQ8    820   DDX23_HUMAN Probable ATP-dependent RNA helica...1100.67     38.5     28     45GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0005682; C:U5 snRNP; IDA:HGNC.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0000354; P:cis assembly of pre-catalytic spliceosome; IC:HGNC.
330Q7ZY47    947   DDX42_XENLA ATP-dependent RNA helicase DDX42 ...1700.67     38.5     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
331A3D9I5    438   RHLB_SHEB5 ATP-dependent RNA helicase rhlB OS...1130.69     38.1     27     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
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