Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR518W
Length:
517
Number of sequences:
5887
Description:
YDR518W EUG1 SGDID:S000002926, Chr IV from 1478608-1480161, Genome Release 64-1-1, Verified ORF, "Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q14554    519   PDIA5_HUMAN Protein disulfide-isomerase A5 OS...1030.35     37.4     24     49GO:0005788; C:endoplasmic reticulum lumen; TAS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; TAS:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; TAS:UniProtKB.
92Q2KIL5    521   PDIA5_BOVIN Protein disulfide-isomerase A5 OS...910.62     36.6     24     41GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
93Q9LJU2    483   PDI53_ARATH Protein disulfide-isomerase 5-3 O...720.075     39.3     28     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
94Q11067    440   PDIA6_CAEEL Probable protein disulfide-isomer...1080.012     42     25     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.
95O22022    102   THIO_CYAME Thioredoxin OS=Cyanidioschyzon mer...850.025     38.1     27     44GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
96Q12404    318   MPD1_YEAST Protein disulfide-isomerase MPD1 O...940.003     43.5     26     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0000324; C:fungal-type vacuole; IDA:SGD.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IDA:SGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:SGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IGI:SGD.
97P37395    107   THIO_CYACA Thioredoxin OS=Cyanidium caldarium...821.3     33.1     23     51GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
98P52232    105   THIO1_SYNY3 Thioredoxin-like protein slr0233 ...700.014     38.9     30     53
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
99O83889    105   THIO_TREPA Thioredoxin OS=Treponema pallidum ...684.8     31.6     26     47
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
100Q10N04    147   PDI51_ORYSJ Protein disulfide isomerase-like ...1140.006     40.8     24     43
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
101Q6NRT6    796   DJC10_XENLA DnaJ homolog subfamily C member 1...980.021     41.2     30     48GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IEA:InterPro.
102P12243    107   THIO1_SYNE7 Thioredoxin-1 OS=Synechococcus el...751.7     32.7     23     51
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
103P0A616    116   THIO_MYCTU Thioredoxin OS=Mycobacterium tuber...850.003     41.2     29     56GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005576; C:extracellular region; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0009055; F:electron carrier activity; IDA:MTBBASE.::GO:0015038; F:glutathione disulfide oxidoreductase activity; IDA:MTBBASE.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:MTBBASE.::GO:0080007; F:S-nitrosoglutathione reductase activity; IDA:MTBBASE.
GO:0045454; P:cell redox homeostasis; IDA:MTBBASE.::GO:0006535; P:cysteine biosynthetic process from serine; TAS:Reactome.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IDA:MTBBASE.::GO:0006810; P:transport; IEA:UniProtKB-KW.
104P0A617    116   THIO_MYCBO Thioredoxin OS=Mycobacterium bovis...850.003     41.2     29     56
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
105Q7KQL8    104   THIO_PLAF7 Thioredoxin OS=Plasmodium falcipar...690.16     35.8     30     48
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
106Q5JMR9    168   TRXY_ORYSJ Thioredoxin Y, chloroplastic OS=Or...850.002     42.4     27     52
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
107P0A4L1    107   THIO1_NOSS1 Thioredoxin-1 OS=Nostoc sp. (stra...960.083     36.6     24     46
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
108P0A4L2    107   THIO1_ANASO Thioredoxin-1 OS=Anabaena sp. (st...960.083     36.6     24     46
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
109Q8GYD1    146   PDI51_ARATH Protein disulfide-isomerase 5-1 O...1330.00007     46.6     26     44
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
110O84544    102   THIO_CHLTR Thioredoxin OS=Chlamydia trachomat...670.42     34.7     28     45
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
111Q9Z7P5    102   THIO_CHLPN Thioredoxin OS=Chlamydia pneumonia...673.5     32     30     46
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
112Q96JJ7    454   TMX3_HUMAN Protein disulfide-isomerase TMX3 O...1040.0007     45.8     30     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
113Q9DC23    793   DJC10_MOUSE DnaJ homolog subfamily C member 1...981.8     35     27     42GO:0034663; C:endoplasmic reticulum chaperone complex; ISS:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:UniProtKB.
GO:0001671; F:ATPase activator activity; IMP:UniProtKB.::GO:0051117; F:ATPase binding; IPI:UniProtKB.::GO:0051087; F:chaperone binding; IDA:UniProtKB.::GO:0015036; F:disulfide oxidoreductase activity; IDA:UniProtKB.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051787; F:misfolded protein binding; ISS:UniProtKB.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.
114Q8BXZ1    456   TMX3_MOUSE Protein disulfide-isomerase TMX3 O...1120.0008     45.4     30     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
115Q4N4N8    220   TXND_THEPA Thioredoxin domain-containing prot...670.00002     49.7     36     55GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
116P59527    109   THIO_BUCBP Thioredoxin OS=Buchnera aphidicola...720.18     35.8     28     49
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
117Q498R3    793   DJC10_RAT DnaJ homolog subfamily C member 10 ...590.0004     47     32     56GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006457; P:protein folding; IEA:InterPro.
118Q8L7S9    167   TRXY2_ARATH Thioredoxin Y2, chloroplastic OS=...800.0001     46.2     30     54GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0009416; P:response to light stimulus; IEP:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
119Q9CM49    106   THIO_PASMU Thioredoxin OS=Pasteurella multoci...751.4     33.1     28     49
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
120P80579    105   THIO_ALIAC Thioredoxin OS=Alicyclobacillus ac...780.0003     44.3     33     49
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
121P50254    107   THIO_PORYE Thioredoxin OS=Porphyra yezoensis....951.1     33.5     21     48GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
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