UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR518W

Length:

517

Number of sequences:

5887

Description:

YDR518W EUG1 SGDID:S000002926, Chr IV from 1478608-1480161, Genome Release 64-1-1, Verified ORF, "Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
181	Q5HQ29	104	THIO_STAEQ Thioredoxin OS=Staphylococcus epid...	85	0.004	40.8	31	47
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
182	Q43636	118	TRXH_RICCO Thioredoxin H-type OS=Ricinus comm...	87	0.001	42.4	31	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
183	Q6IUU3	750	QSOX1_RAT Sulfhydryl oxidase 1 OS=Rattus norv...	64	0.23	38.1	28	55	GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0030173; C:integral to Golgi membrane; ISS:UniProtKB.
									GO:0016971; F:flavin-linked sulfhydryl oxidase activity; ISS:UniProtKB.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; ISS:UniProtKB.
184	Q9R6P9	100	THIO_MYCGA Thioredoxin OS=Mycoplasma gallisep...	83	0.038	37.7	29	46
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
185	Q4L5F0	104	THIO_STAHJ Thioredoxin OS=Staphylococcus haem...	88	0.013	39.3	28	53
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
186	P00275	105	THIO1_CORNE Thioredoxin C-1 OS=Corynebacteriu...	68	0.55	34.3	32	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
187	Q8BND5	748	QSOX1_MOUSE Sulfhydryl oxidase 1 OS=Mus muscu...	64	0.15	38.5	28	55	GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0030173; C:integral to Golgi membrane; ISS:UniProtKB.
									GO:0016971; F:flavin-linked sulfhydryl oxidase activity; ISS:UniProtKB.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; ISS:UniProtKB.
188	O14463	103	TRX1_SCHPO Thioredoxin-1 OS=Schizosaccharomyc...	85	0.37	34.7	28	47	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0016209; F:antioxidant activity; IDA:PomBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:PomBase.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034614; P:cellular response to reactive oxygen species; IDA:PomBase.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IDA:PomBase.::GO:0090329; P:regulation of DNA-dependent DNA replication; ISS:PomBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
189	Q7M1B9	110	THIO_CHLAA Thioredoxin OS=Chloroflexus aurant...	70	0.002	41.6	31	56
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
190	P22217	103	TRX1_YEAST Thioredoxin-1 OS=Saccharomyces cer...	76	1	33.5	28	46	GO:0005829; C:cytosol; IDA:SGD.::GO:0000324; C:fungal-type vacuole; IPI:SGD.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; TAS:SGD.::GO:0009263; P:deoxyribonucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:SGD.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0080058; P:protein deglutathionylation; IDA:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006275; P:regulation of DNA replication; IGI:SGD.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IDA:SGD.::GO:0042144; P:vacuole fusion, non-autophagic; IDA:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.
191	P57653	108	THIO_BUCAI Thioredoxin OS=(Acyrthosiphon pisu...	91	1.4	33.1	23	48
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
192	Q9X2T1	108	THIO_PSEAE Thioredoxin OS=12228). GN=trxA Syn...	65	0.47	34.7	28	55
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
193	Q7TN22	820	TXD16_MOUSE Thioredoxin domain-containing pro...	91	1.6	35.4	29	49	GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
194	A4FUW8	957	TXD11_BOVIN Thioredoxin domain-containing pro...	71	0.17	38.5	30	46	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
195	Q69AB1	127	TXND8_RAT Thioredoxin domain-containing prote...	78	0.003	41.6	29	55	GO:0001669; C:acrosomal vesicle; IDA:RGD.::GO:0019861; C:flagellum; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:RGD.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0001675; P:acrosome assembly; IEP:RGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
196	Q6PKC3	985	TXD11_HUMAN Thioredoxin domain-containing pro...	71	1.2	35.8	30	44	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
197	P52228	145	THIO3_CORNE Thioredoxin C-3 OS=Corynebacteriu...	73	2.1	33.5	29	48
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
198	P07887	108	THIO2_CORNE Thioredoxin C-2 OS=Corynebacteriu...	73	0.021	38.5	29	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
199	Q6XHI1	106	THIO2_DROYA Thioredoxin-2 OS=Drosophila yakub...	106	6.8	31.2	25	43
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
200	P20857	111	THIO2_NOSS1 Thioredoxin-2 OS=Nostoc sp. (stra...	65	0.65	34.3	28	52
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
201	Q8LD49	182	TRXX_ARATH Thioredoxin X, chloroplastic OS=Ar...	76	1.6	34.3	32	46	GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IDA:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
202	Q9H3N1	280	TMX1_HUMAN Thioredoxin-related transmembrane ...	104	0.006	42.4	23	49	GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
									GO:0030612; F:arsenate reductase (thioredoxin) activity; NAS:UniProtKB.::GO:0015036; F:disulfide oxidoreductase activity; IDA:UniProtKB.
									GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006260; P:DNA replication; NAS:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:UniProtKB.::GO:0045321; P:leukocyte activation; NAS:UniProtKB.::GO:0045927; P:positive regulation of growth; NAS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006950; P:response to stress; NAS:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.
203	P10473	104	THIO_RHORU Thioredoxin OS=Rhodospirillum rubr...	78	0.32	35	27	49
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
204	O17486	107	THIO_ECHGR Thioredoxin OS=Echinococcus granul...	73	0.007	40	30	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
205	Q17424	145	THIO2_CAEEL Probable thioredoxin-2 OS=Caenorh...	90	0.007	40.4	29	52
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
206	Q8VBT0	278	TMX1_MOUSE Thioredoxin-related transmembrane ...	82	0.007	42	28	52	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
207	O00391	747	QSOX1_HUMAN Sulfhydryl oxidase 1 OS=Homo sapi...	96	0.008	42.7	31	44	GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0030173; C:integral to Golgi membrane; IDA:UniProtKB.
									GO:0016971; F:flavin-linked sulfhydryl oxidase activity; IDA:UniProtKB.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IDA:UniProtKB.
208	Q9ZP20	172	TRXM5_ORYSJ Thioredoxin M5, chloroplastic OS=...	86	0.11	37.4	24	45	GO:0009507; C:chloroplast; IDA:UniProtKB.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0042744; P:hydrogen peroxide catabolic process; IMP:UniProtKB.::GO:0009657; P:plastid organization; IMP:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
209	P0AA30	109	THIO_SHIFL Thioredoxin-1 OS=Shigella flexneri...	88	0.043	37.7	30	47
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
210	P0AA28	109	THIO_SALTY Thioredoxin-1 OS=Salmonella typhim...	88	0.043	37.7	30	47
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
211	P0AA29	109	THIO_SALTI Thioredoxin-1 OS=Salmonella typhi....	88	0.043	37.7	30	47
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.

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