UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR518W

Length:

517

Number of sequences:

5887

Description:

YDR518W EUG1 SGDID:S000002926, Chr IV from 1478608-1480161, Genome Release 64-1-1, Verified ORF, "Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
121	P50254	107	THIO_PORYE Thioredoxin OS=Porphyra yezoensis....	95	1.1	33.5	21	48	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
122	Q5R875	454	TMX3_PONAB Protein disulfide-isomerase TMX3 O...	104	0.0003	46.6	30	48	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
123	P46843	458	TRXB_MYCLE Bifunctional thioredoxin reductase...	74	0.001	45.1	30	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0019430; P:removal of superoxide radicals; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
124	Q9PJK3	102	THIO_CHLMU Thioredoxin OS=Chlamydia muridarum...	66	2.1	32.7	30	45
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
125	Q8IXB1	793	DJC10_HUMAN DnaJ homolog subfamily C member 1...	74	0.0004	47	30	50	GO:0034663; C:endoplasmic reticulum chaperone complex; IDA:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
									GO:0001671; F:ATPase activator activity; ISS:UniProtKB.::GO:0051117; F:ATPase binding; IPI:UniProtKB.::GO:0051087; F:chaperone binding; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051787; F:misfolded protein binding; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; IDA:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030433; P:ER-associated protein catabolic process; IMP:UniProtKB.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:UniProtKB.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
126	Q5R5L3	793	DJC10_PONAB DnaJ homolog subfamily C member 1...	74	0.0003	47	30	50	GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IEA:InterPro.
127	Q50KB1	223	SEP2_EMIHU Protein disulfide-isomerase-like p...	76	0.008	41.6	30	51	GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
									GO:0003756; F:protein disulfide isomerase activity; NAS:UniProtKB.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
128	Q1RKN1	105	THIO_RICBR Thioredoxin OS=Rickettsia bellii (...	82	0.006	40.4	28	46
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
129	P51225	107	THIO_PORPU Thioredoxin OS=Porphyra purpurea. ...	95	4.4	31.6	20	47	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
130	Q4UNK3	105	THIO_RICFE Thioredoxin OS=Rickettsia felis (s...	73	0.006	40	32	47
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
131	P52227	102	THIO_CHLCV Thioredoxin OS=Chlamydophila cavia...	106	0.00005	46.6	31	56
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
132	P50338	109	THIO_GRIPA Thioredoxin OS=Griffithsia pacific...	86	3.3	32	21	51	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
133	P52231	107	THIO_SYNY3 Thioredoxin OS=Synechocystis sp. (...	73	1.2	33.5	25	45
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
134	Q7XKD0	180	TRXX_ORYSJ Thioredoxin X, chloroplastic OS=Or...	121	0.00007	47	26	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
135	Q6GNG3	452	TMX3_XENLA Protein disulfide-isomerase TMX3 O...	100	0.012	42	29	47	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
136	Q95108	166	THIOM_BOVIN Thioredoxin, mitochondrial OS=Bos...	94	0.00007	46.6	29	56	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
137	Q99316	277	MPD2_YEAST Protein disulfide isomerase MPD2 O...	90	0.00007	48.1	32	49	GO:0005783; C:endoplasmic reticulum; IGI:SGD.
									GO:0003756; F:protein disulfide isomerase activity; IDA:SGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:SGD.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006457; P:protein folding; IGI:SGD.
138	P23400	140	TRXM_CHLRE Thioredoxin M-type, chloroplastic ...	87	0.089	37.4	26	46	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
139	P43785	107	THIO_HAEIN Thioredoxin OS=Haemophilus influen...	87	0.14	36.2	29	44
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
140	Q8JGM4	743	QSOX1_CHICK Sulfhydryl oxidase 1 OS=Gallus ga...	112	0.037	40.4	28	45	GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0016971; F:flavin-linked sulfhydryl oxidase activity; ISS:UniProtKB.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; ISS:UniProtKB.
141	Q9UW02	106	THIO_COPCM Thioredoxin OS=Coprinus comatus (S...	68	1.2	33.1	24	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
142	P10472	108	THIO_CHLLT Thioredoxin OS=Chlorobium limicola...	71	0.24	35.4	30	44
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
143	P52233	108	THIO_THIFE Thioredoxin OS=Thiobacillus ferroo...	84	0.005	40.4	30	55
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
144	P33791	106	THIO_STRAU Thioredoxin OS=Streptomyces aureof...	85	0.005	40.4	31	47
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
145	P97615	166	THIOM_RAT Thioredoxin, mitochondrial OS=Rattu...	94	0.0002	45.8	29	56	GO:0030425; C:dendrite; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0031669; P:cellular response to nutrient levels; IEP:RGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009725; P:response to hormone stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0006979; P:response to oxidative stress; IEP:RGD.::GO:0006810; P:transport; IEA:UniProtKB-KW.
146	P97493	166	THIOM_MOUSE Thioredoxin, mitochondrial OS=Mus...	94	0.0002	45.8	29	56	GO:0005739; C:mitochondrion; IDA:MGI.
									GO:0009055; F:electron carrier activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
147	Q9CAS1	148	TRXH8_ARATH Thioredoxin H8 OS=Arabidopsis tha...	97	0.0002	45.4	31	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
148	Q99757	166	THIOM_HUMAN Thioredoxin, mitochondrial OS=Hom...	94	0.0002	45.4	29	56	GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
									GO:0009055; F:electron carrier activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
149	Q6NPF9	172	TRXY1_ARATH Thioredoxin Y1, chloroplastic OS=...	80	0.0002	45.4	30	55	GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
150	Q9ZEE0	105	THIO_RICPR Thioredoxin OS=Rickettsia prowazek...	73	0.058	37.4	29	45
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
151	P07591	181	TRXM_SPIOL Thioredoxin M-type, chloroplastic ...	106	9.1	32	23	42	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.

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