Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR516C
Length:
500
Number of sequences:
5887
Description:
YDR516C EMI2 SGDID:S000002924, Chr IV from 1476476-1474974, Genome Release 64-1-1, reverse complement, Verified ORF, "Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1; required for sporulation; expression is regulated by glucose-repression transcription factors Mig1/2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P27881    917   HXK2_RAT Hexokinase-2 OS=Rattus norvegicus (R...4741e-57     209     36     51GO:0005741; C:mitochondrial outer membrane; TAS:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005536; F:glucose binding; IDA:RGD.::GO:0004396; F:hexokinase activity; IDA:RGD.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0007595; P:lactation; IEP:RGD.
32Q9NFT7    486   HXK2_DROME Hexokinase type 2 OS=Drosophila me...4363e-62     216     34     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; NAS:UniProtKB.
GO:0006096; P:glycolysis; NAS:UniProtKB.
33O08528    917   HXK2_MOUSE Hexokinase-2 OS=Mus musculus (Mous...4747e-58     210     36     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:MGI.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0046324; P:regulation of glucose import; IMP:MGI.
34P27926    924   HXK3_RAT Hexokinase-3 OS=Rattus norvegicus (R...4876e-54     199     32     49GO:0043234; C:protein complex; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:RGD.::GO:0004396; F:hexokinase activity; IDA:RGD.::GO:0042562; F:hormone binding; IPI:RGD.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
35P05708    918   HXK1_RAT Hexokinase-1 OS=Rattus norvegicus (R...4444e-49     185     31     50GO:0005901; C:caveola; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0016887; F:ATPase activity; IC:RGD.::GO:0004340; F:glucokinase activity; IDA:RGD.::GO:0005536; F:glucose binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004672; F:protein kinase activity; IDA:RGD.
GO:0006096; P:glycolysis; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:RGD.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0010359; P:regulation of anion channel activity; IDA:RGD.
36P19367    917   HXK1_HUMAN Hexokinase-1 OS=Homo sapiens (Huma...4446e-51     190     32     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; TAS:ProtInc.
GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; TAS:ProtInc.::GO:0055085; P:transmembrane transport; TAS:Reactome.
37A2PYL6    917   HXK2_HORSE Hexokinase-2 OS=Equus caballus (Ho...4743e-55     203     35     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
38A2PYL7    917   HXK2_EQUZE Hexokinase-2 OS=Equus zebra (Mount...4743e-55     203     35     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
39A2PYL8    917   HXK2_EQUGR Hexokinase-2 OS=Equus grevyi (Grev...4743e-55     203     35     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
40P27595    918   HXK1_BOVIN Hexokinase-1 OS=Bos taurus (Bovine...4442e-39     157     29     48GO:0005829; C:cytosol; ISS:AgBase.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; ISS:AgBase.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
41Q5RC71    917   HXK1_PONAB Hexokinase-1 OS=Pongo abelii (Suma...4441e-50     189     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
42Q3TRM8    922   HXK3_MOUSE Hexokinase-3 OS=Mus musculus (Mous...4876e-46     176     31     48GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
43Q5W676    507   HXK5_ORYSJ Hexokinase-5 OS=Oryza sativa subsp...4896e-61     214     36     49GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
44Q2KNB4    500   HXK3_ORYSJ Hexokinase-3 OS=Oryza sativa subsp...4821e-60     213     35     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
45Q1W674    917   HXK2_PIG Hexokinase-2 OS=Sus scrofa (Pig). GN...4742e-57     209     36     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
46Q2KNB9    494   HXK2_ORYSJ Hexokinase-2 OS=Oryza sativa subsp...4365e-59     208     36     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
47Q9LPS1    498   HXK3_ARATH Hexokinase-3 OS=Arabidopsis thalia...4996e-57     202     33     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0009536; C:plastid; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
48Q8LH82    498   HXK1_ORYSJ Hexokinase-1 OS=Oryza sativa subsp...4361e-55     199     35     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
49P52792    465   HXK4_MOUSE Glucokinase OS=Mus musculus (Mouse...4943e-54     194     30     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB.
GO:0070509; P:calcium ion import; IMP:UniProtKB.::GO:0001678; P:cellular glucose homeostasis; IMP:MGI.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006739; P:NADP metabolic process; IMP:MGI.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0043266; P:regulation of potassium ion transport; IMP:MGI.
50P35557    465   HXK4_HUMAN Glucokinase OS=Homo sapiens (Human...4963e-53     192     31     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004340; F:glucokinase activity; IDA:UniProtKB.::GO:0005536; F:glucose binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; ISS:BHF-UCL.::GO:0051594; P:detection of glucose; IMP:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0045721; P:negative regulation of gluconeogenesis; IMP:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0010827; P:regulation of glucose transport; TAS:Reactome.::GO:0006110; P:regulation of glycolysis; NAS:BHF-UCL.::GO:0055085; P:transmembrane transport; TAS:Reactome.
51P17712    465   HXK4_RAT Glucokinase OS=Rattus norvegicus (Ra...4943e-53     191     30     50GO:0044448; C:cell cortex part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005654; C:nucleoplasm; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.
GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0019903; F:protein phosphatase binding; IPI:RGD.
GO:0001678; P:cellular glucose homeostasis; IMP:RGD.::GO:0042149; P:cellular response to glucose starvation; IMP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; IDA:BHF-UCL.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IDA:RGD.::GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IDA:RGD.::GO:0005978; P:glycogen biosynthetic process; IDA:RGD.::GO:0006096; P:glycolysis; IDA:RGD.::GO:0032811; P:negative regulation of epinephrine secretion; IMP:RGD.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:RGD.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IDA:RGD.::GO:0019932; P:second-messenger-mediated signaling; IDA:RGD.
52Q56XE8    502   HXK4_ARATH Hexokinase-4 OS=Arabidopsis thalia...4495e-51     186     33     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
53Q2KNB5    504   HXK10_ORYSJ Hexokinase-10 OS=Oryza sativa sub...4472e-49     182     35     50GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
54O64390    498   HXK1_SOLTU Hexokinase-1 OS=Solanum tuberosum ...4223e-46     173     33     47GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
55Q02155    493   HXK_PLAFA Hexokinase OS=Plasmodium falciparum...5063e-39     153     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
56Q969A8    468   HXK_TOXGO Hexokinase OS=Toxoplasma gondii. GN...4842e-34     138     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
57Q9T071    493   HXKL2_ARATH Probable hexokinase-like 2 protei...4463e-28     120     26     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0006974; P:response to DNA damage stimulus; IEP:TAIR.::GO:0009408; P:response to heat; IEP:TAIR.::GO:0006979; P:response to oxidative stress; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0010224; P:response to UV-B; IEP:TAIR.::GO:0009414; P:response to water deprivation; IEP:TAIR.
58Q9NFT9    465   HXK1_DROME Hexokinase type 1 OS=Drosophila me...4434e-28     119     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
59Q4U3Y2    549   HXK1_ASPFU Hexokinase-1 OS=A1100) (Aspergillu...4285e-28     120     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
60A3D8T3    284   Y3671_SHEB5 UPF0042 nucleotide-binding protei...660.5     36.2     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
61A9L0Z2    284   Y713_SHEB9 UPF0042 nucleotide-binding protein...660.5     36.2     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
records
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