rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
781 | O75385 | 1050 | ULK1_HUMAN Serine/threonine-protein kinase UL... | 230 | 2e-27 | 124 | 36 | 53 | GO:0005776; C:autophagic vacuole; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.::GO:0070969; C:ULK1-ATG13-FIP200 complex; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB. | 782 | P21901 | 351 | KAPL_APLCA Spermatozoon-associated protein ki... | 295 | 2e-27 | 119 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 783 | Q13233 | 1512 | M3K1_HUMAN Mitogen-activated protein kinase k... | 283 | 2e-27 | 124 | 30 | 50 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome. | 784 | Q8K1R7 | 984 | NEK9_MOUSE Serine/threonine-protein kinase Ne... | 201 | 2e-27 | 124 | 37 | 57 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 785 | P31749 | 480 | AKT1_HUMAN RAC-alpha serine/threonine-protein... | 269 | 2e-27 | 120 | 31 | 52 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0030235; F:nitric-oxide synthase regulator activity; IMP:BHF-UCL.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0006924; P:activation-induced cell death of T cells; IMP:MGI.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0060644; P:mammary gland epithelial cell differentiation; TAS:UniProtKB.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0031999; P:negative regulation of fatty acid beta-oxidation; IMP:BHF-UCL.::GO:0010748; P:negative regulation of plasma membrane long-chain fatty acid transport; IMP:BHF-UCL.::GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006809; P:nitric oxide biosynthetic process; TAS:ProtInc.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0031659; P:positive regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:BHF-UCL.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0045600; P:positive regulation of fat cell differentiation; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:BHF-UCL.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:BHF-UCL.::GO:0051000; P:positive regulation of nitric-oxide synthase activity; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IMP:UniProtKB.::GO:2001047; P:regulation of G1/S transition checkpoint; TAS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0034405; P:response to fluid shear stress; IMP:BHF-UCL.::GO:0009408; P:response to heat; TAS:ProtInc.::GO:0070141; P:response to UV-A; IDA:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 786 | Q2VWQ3 | 642 | STE20_PENMA Serine/threonine-protein kinase p... | 213 | 3e-27 | 122 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 787 | O19111 | 591 | KPCZ_RABIT Protein kinase C zeta type OS=Oryc... | 264 | 3e-27 | 122 | 31 | 51 | GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:UniProtKB.::GO:0046628; P:positive regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:2001181; P:positive regulation of interleukin-10 secretion; ISS:UniProtKB.::GO:2000667; P:positive regulation of interleukin-13 secretion; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:2000664; P:positive regulation of interleukin-5 secretion; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:2000553; P:positive regulation of T-helper 2 cell cytokine production; ISS:UniProtKB.::GO:0045630; P:positive regulation of T-helper 2 cell differentiation; ISS:UniProtKB. | 788 | Q551H4 | 1028 | FRAY2_DICDI Serine/threonine-protein kinase f... | 279 | 3e-27 | 124 | 29 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 789 | Q7YQL3 | 559 | PAK3_PONPY Serine/threonine-protein kinase PA... | 269 | 3e-27 | 121 | 28 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 790 | Q7YQL4 | 559 | PAK3_PANTR Serine/threonine-protein kinase PA... | 269 | 3e-27 | 121 | 28 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 791 | O75914 | 559 | PAK3_HUMAN Serine/threonine-protein kinase PA... | 269 | 3e-27 | 121 | 28 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; TAS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; IDA:UniProtKB.::GO:0050808; P:synapse organization; TAS:UniProtKB. | 792 | Q0WPH8 | 956 | NEK5_ARATH Serine/threonine-protein kinase Ne... | 217 | 3e-27 | 123 | 30 | 53 | GO:0055028; C:cortical microtubule; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009913; P:epidermal cell differentiation; IMP:TAIR.::GO:0007017; P:microtubule-based process; IMP:TAIR. | 793 | P31750 | 480 | AKT1_MOUSE RAC-alpha serine/threonine-protein... | 269 | 3e-27 | 120 | 31 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005819; C:spindle; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0042640; P:anagen; IMP:MGI.::GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.::GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0015758; P:glucose transport; IMP:UniProtKB.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0060709; P:glycogen cell development involved in embryonic placenta development; IMP:MGI.::GO:0006954; P:inflammatory response; IDA:MGI.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060716; P:labyrinthine layer blood vessel development; IMP:MGI.::GO:0001893; P:maternal placenta development; IMP:MGI.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0032287; P:peripheral nervous system myelin maintenance; IMP:MGI.::GO:0045768; P:positive regulation of anti-apoptosis; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0010765; P:positive regulation of sodium ion transport; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0030163; P:protein catabolic process; IDA:MGI.::GO:0016567; P:protein ubiquitination; IDA:MGI.::GO:0010975; P:regulation of neuron projection development; IDA:UniProtKB.::GO:0045884; P:regulation of survival gene product expression; IDA:MGI.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0032094; P:response to food; IDA:MGI.::GO:0051146; P:striated muscle cell differentiation; IGI:MGI. | 794 | P47196 | 480 | AKT1_RAT RAC-alpha serine/threonine-protein k... | 269 | 3e-27 | 120 | 31 | 51 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007568; P:aging; IDA:RGD.::GO:0030030; P:cell projection organization; IDA:MGI.::GO:0071456; P:cellular response to hypoxia; IDA:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045792; P:negative regulation of cell size; IDA:MGI.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IDA:RGD.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0030307; P:positive regulation of cell growth; IDA:RGD.::GO:0045907; P:positive regulation of vasoconstriction; IMP:RGD.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0006412; P:translation; IMP:UniProtKB. | 795 | Q4P5N0 | 746 | STE20_USTMA Serine/threonine-protein kinase S... | 233 | 3e-27 | 122 | 31 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 796 | Q94CU5 | 943 | NEK5_ORYSJ Serine/threonine-protein kinase Ne... | 216 | 3e-27 | 123 | 31 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 797 | A7TIZ4 | 994 | ATG1_VANPO Serine/threonine-protein kinase at... | 260 | 3e-27 | 123 | 32 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 798 | P32023 | 934 | KGP25_DROME cGMP-dependent protein kinase, is... | 259 | 4e-27 | 123 | 32 | 53 | GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046959; P:habituation; IMP:FlyBase.::GO:0030536; P:larval feeding behavior; IMP:UniProtKB.::GO:0008345; P:larval locomotory behavior; IMP:FlyBase.::GO:0007616; P:long-term memory; IMP:FlyBase.::GO:0008016; P:regulation of heart contraction; IMP:FlyBase.::GO:0032095; P:regulation of response to food; IMP:FlyBase.::GO:0009744; P:response to sucrose stimulus; IDA:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase. | 799 | Q6P0Q8 | 1798 | MAST2_HUMAN Microtubule-associated serine/thr... | 282 | 4e-27 | 124 | 32 | 49 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045075; P:regulation of interleukin-12 biosynthetic process; ISS:UniProtKB.::GO:0048515; P:spermatid differentiation; ISS:UniProtKB. | 800 | Q811L6 | 2618 | MAST4_MOUSE Microtubule-associated serine/thr... | 222 | 4e-27 | 124 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 801 | Q6H9I1 | 952 | ATG1_BOTFU Serine/threonine-protein kinase AT... | 328 | 5e-27 | 122 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 802 | A6RYB8 | 952 | ATG1_BOTFB Serine/threonine-protein kinase at... | 328 | 5e-27 | 122 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 803 | P53349 | 1493 | M3K1_MOUSE Mitogen-activated protein kinase k... | 283 | 5e-27 | 123 | 30 | 50 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL. | 804 | Q18846 | 772 | KS6A2_CAEEL Putative ribosomal protein S6 kin... | 270 | 2e-23 | 110 | 30 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0002119; P:nematode larval development; IMP:WormBase. | 805 | Q98TY9 | 481 | AKT1_XENLA RAC-alpha serine/threonine-protein... | 272 | 5e-27 | 120 | 31 | 51 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0015758; P:glucose transport; ISS:UniProtKB.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB. | 806 | Q8CDB0 | 459 | MKNK2_MOUSE MAP kinase-interacting serine/thr... | 323 | 5e-27 | 119 | 31 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 807 | P05128 | 682 | KPCG_BOVIN Protein kinase C gamma type OS=Bos... | 262 | 5e-27 | 122 | 32 | 50 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB. | 808 | P23647 | 805 | FUSED_DROME Serine/threonine-protein kinase f... | 273 | 5e-27 | 122 | 32 | 51 | GO:0035301; C:Hedgehog signaling complex; IPI:FlyBase.::GO:0016020; C:membrane; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase. | | | | | | | | | | GO:0007293; P:germarium-derived egg chamber formation; IMP:FlyBase.::GO:0007228; P:positive regulation of hh target transcription factor activity; IMP:FlyBase.::GO:0042993; P:positive regulation of transcription factor import into nucleus; IMP:FlyBase.::GO:0031647; P:regulation of protein stability; IDA:FlyBase.::GO:0030162; P:regulation of proteolysis; NAS:FlyBase.::GO:0007367; P:segment polarity determination; IMP:FlyBase. | 809 | P31748 | 501 | AKT_MLVAT AKT kinase-transforming protein OS=... | 269 | 6e-27 | 119 | 31 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 810 | Q6CVA2 | 989 | STE20_KLULA Serine/threonine-protein kinase S... | 238 | 6e-27 | 122 | 31 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019236; P:response to pheromone; IEA:UniProtKB-KW. | 811 | Q86IX1 | 737 | DST1_DICDI Serine/threonine-protein kinase ds... | 289 | 7e-27 | 121 | 29 | 50 | GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase. |