Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR490C
Length:
766
Number of sequences:
5887
Description:
YDR490C PKH1 SGDID:S000002898, Chr IV from 1434268-1431968, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
841O14408    382   KCC1_METAN Calcium/calmodulin-dependent prote...2971e-23     107     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
842Q8SWM6    488   CDC5_ENCCU Probable cell cycle serine/threoni...2661e-23     108     28     49GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
843P43291    363   SRK2A_ARATH Serine/threonine-protein kinase S...2761e-23     107     29     47GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009737; P:response to abscisic acid stimulus; IDA:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR.
844P51956    506   NEK3_HUMAN Serine/threonine-protein kinase Ne...2661e-23     108     30     50GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; NAS:UniProtKB.
845Q9N0P9    313   PIM1_BOVIN Serine/threonine-protein kinase pi...2771e-23     106     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
846Q9Y6R4    1608   M3K4_HUMAN Mitogen-activated protein kinase k...3061e-23     110     29     47GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.
847Q91ZR4    698   NEK8_MOUSE Serine/threonine-protein kinase Ne...2611e-23     110     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
848P18431    1067   SGG_DROME Protein kinase shaggy OS=Drosophila...3441e-23     110     28     45GO:0045169; C:fusome; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.
GO:0008407; P:chaeta morphogenesis; NAS:FlyBase.::GO:0035293; P:chitin-based larval cuticle pattern formation; IMP:FlyBase.::GO:0009649; P:entrainment of circadian clock; IMP:FlyBase.::GO:0003382; P:epithelial cell morphogenesis; IMP:FlyBase.::GO:0090163; P:establishment of epithelial cell planar polarity; IMP:FlyBase.::GO:0046959; P:habituation; IMP:FlyBase.::GO:0007507; P:heart development; NAS:FlyBase.::GO:0045475; P:locomotor rhythm; NAS:FlyBase.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:FlyBase.::GO:0045879; P:negative regulation of smoothened signaling pathway; IDA:FlyBase.::GO:0045886; P:negative regulation of synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; TAS:FlyBase.::GO:0007219; P:Notch signaling pathway; TAS:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0030707; P:ovarian follicle cell development; IMP:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0042306; P:regulation of protein import into nucleus; TAS:FlyBase.::GO:0030162; P:regulation of proteolysis; IDA:FlyBase.::GO:0072347; P:response to anesthetic; IMP:FlyBase.::GO:0007367; P:segment polarity determination; IMP:FlyBase.::GO:0035019; P:somatic stem cell maintenance; IMP:FlyBase.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0035309; P:wing and notum subfield formation; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; TAS:FlyBase.
849Q54TW2    686   PDPKA_DICDI Probable serine/threonine-protein...1122e-23     109     46     63
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
850Q8FUI5    660   PKN1_COREF Probable serine/threonine-protein ...2362e-23     109     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
851Q55FT4    2247   TSUA_DICDI Probable serine/threonine-protein ...2762e-23     110     29     51GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase.
852Q8QZX0    417   SBK1_MOUSE Serine/threonine-protein kinase SB...3052e-23     107     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
853Q9Z335    417   SBK1_RAT Serine/threonine-protein kinase SBK1...3052e-23     107     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0007420; P:brain development; IEP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:RGD.
854Q8K045    878   PKN3_MOUSE Serine/threonine-protein kinase N3...2932e-23     110     27     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0007165; P:signal transduction; IEA:InterPro.
855Q10GB1    599   NEK1_ORYSJ Serine/threonine-protein kinase Ne...2782e-23     109     30     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
856P49071    359   MAPK2_DROME MAP kinase-activated protein kina...2842e-23     106     31     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.
GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.
857Q9QYZ6    504   SMK2A_MOUSE Sperm motility kinase 2A OS=Mus m...2612e-23     108     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
858Q52EB3    982   ATG1_MAGO7 Serine/threonine-protein kinase AT...3432e-23     110     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:PAMGO_MGG.
GO:0048102; P:autophagic cell death; IMP:PAMGO_MGG.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0044409; P:entry into host; IMP:PAMGO_MGG.::GO:0009405; P:pathogenesis; IMP:PAMGO_MGG.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0009847; P:spore germination; IMP:PAMGO_MGG.
859P07313    608   MYLK2_RABIT Myosin light chain kinase 2, skel...2732e-23     108     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:BHF-UCL.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:BHF-UCL.::GO:0004687; F:myosin light chain kinase activity; IDA:BHF-UCL.
GO:0032971; P:regulation of muscle filament sliding; IC:BHF-UCL.
860Q1ZXH2    1142   FHKB_DICDI Probable serine/threonine-protein ...2872e-23     110     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
861Q55C57    473   GLKA_DICDI Probable serine/threonine-protein ...3142e-23     107     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005977; P:glycogen metabolic process; ISS:dictyBase.
862O70444    326   PIM3_RAT Serine/threonine-protein kinase pim-...2742e-23     106     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016572; P:histone phosphorylation; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.
863Q39193    361   SRK2I_ARATH Serine/threonine-protein kinase S...2772e-23     106     27     47GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0009789; P:positive regulation of abscisic acid mediated signaling pathway; IGI:TAIR.::GO:0010029; P:regulation of seed germination; IGI:TAIR.::GO:0009739; P:response to gibberellin stimulus; IGI:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR.
864A2YNT8    339   SAPK2_ORYSI Serine/threonine-protein kinase S...2032e-23     106     33     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
865Q9UEE5    414   ST17A_HUMAN Serine/threonine-protein kinase 1...2832e-23     107     25     48GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
866Q13233    1512   M3K1_HUMAN Mitogen-activated protein kinase k...2742e-23     110     26     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
867Q86V86    326   PIM3_HUMAN Serine/threonine-protein kinase pi...2742e-23     105     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.
868Q5QN75    355   M2K1_ORYSJ Mitogen-activated protein kinase k...3472e-23     106     24     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
869Q02066    332   AAIP_WHEAT Abscisic acid-inducible protein ki...2703e-23     105     28     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
870Q08942    431   NRKA_TRYBB Putative serine/threonine-protein ...2633e-23     107     30     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
871Q8N568    766   DCLK2_HUMAN Serine/threonine-protein kinase D...2773e-23     109     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
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