Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR490C
Length:
766
Number of sequences:
5887
Description:
YDR490C PKH1 SGDID:S000002898, Chr IV from 1434268-1431968, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
811Q9CAU7    606   NEK2_ARATH Serine/threonine-protein kinase Ne...2735e-24     111     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
812Q96RR4    588   KKCC2_HUMAN Calcium/calmodulin-dependent prot...3115e-24     110     28     45GO:0005737; C:cytoplasm; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; TAS:UniProtKB.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; TAS:UniProtKB.
GO:0019722; P:calcium-mediated signaling; TAS:UniProtKB.::GO:0000165; P:MAPK cascade; TAS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; TAS:UniProtKB.
813Q7RX99    932   ATG1_NEUCR Serine/threonine-protein kinase at...3435e-24     112     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
814Q6BS08    875   ATG1_DEBHA Serine/threonine-protein kinase AT...3305e-24     111     23     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
815Q9FFP9    360   SRK2H_ARATH Serine/threonine-protein kinase S...2765e-24     108     28     48GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009651; P:response to salt stress; IDA:TAIR.
816P26794    313   PIM1_RAT Serine/threonine-protein kinase pim-...2776e-24     107     29     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
817O80902    431   CIPKM_ARATH CBL-interacting serine/threonine-...2326e-24     108     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
818Q86SG6    692   NEK8_HUMAN Serine/threonine-protein kinase Ne...2616e-24     111     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
819Q9Z2B9    773   KS6A4_MOUSE Ribosomal protein S6 kinase alpha...2937e-24     111     29     47GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0048273; F:mitogen-activated protein kinase p38 binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0043987; P:histone H3-S10 phosphorylation; ISS:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
820A4IFM7    623   MYLK2_BOVIN Myosin light chain kinase 2, skel...2737e-24     110     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
821Q869T7    1176   PAKF_DICDI Serine/threonine-protein kinase pa...2817e-24     111     29     48
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
822Q86IX1    737   DST1_DICDI Serine/threonine-protein kinase ds...2717e-24     111     28     48GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
823Q7TSC3    627   NEK5_MOUSE Serine/threonine-protein kinase Ne...2677e-24     110     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
824Q9JM01    593   CDKL3_RAT Cyclin-dependent kinase-like 3 OS=R...3328e-24     110     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
825Q5XHI9    691   HUNKA_XENLA Hormonally up-regulated neu tumor...2828e-24     110     30     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
826O14757    476   CHK1_HUMAN Serine/threonine-protein kinase Ch...2778e-24     109     28     49GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; IDA:UniProtKB.::GO:0006281; P:DNA repair; IMP:UniProtKB.::GO:0006260; P:DNA replication; TAS:Reactome.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0045839; P:negative regulation of mitosis; IDA:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; IDA:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; ISS:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; IDA:UniProtKB.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; ISS:UniProtKB.::GO:0090399; P:replicative senescence; NAS:BHF-UCL.
827Q8WP15    553   GRK7_PIG G protein-coupled receptor kinase 7 ...3138e-24     110     29     49GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0050254; F:rhodopsin kinase activity; ISS:UniProtKB.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
828Q96PY6    1258   NEK1_HUMAN Serine/threonine-protein kinase Ne...2728e-24     111     29     51GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0000242; C:pericentriolar material; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
829Q95LJ0    313   PIM1_FELCA Serine/threonine-protein kinase pi...2778e-24     107     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
830O35280    476   CHK1_MOUSE Serine/threonine-protein kinase Ch...2778e-24     108     28     48GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005657; C:replication fork; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.
GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0006281; P:DNA repair; IDA:MGI.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:MGI.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; IDA:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; IMP:UniProtKB.
831O75676    772   KS6A4_HUMAN Ribosomal protein S6 kinase alpha...2939e-24     110     30     47GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0048273; F:mitogen-activated protein kinase p38 binding; IGI:UniProtKB.::GO:0004711; F:ribosomal protein S6 kinase activity; NAS:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0043987; P:histone H3-S10 phosphorylation; IMP:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; IMP:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0001818; P:negative regulation of cytokine production; TAS:UniProtKB.::GO:0032793; P:positive regulation of CREB transcription factor activity; TAS:UniProtKB.::GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.::GO:0033129; P:positive regulation of histone phosphorylation; IMP:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
832P58750    326   PIM3_MOUSE Serine/threonine-protein kinase pi...2749e-24     107     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.
833Q8BLF2    595   CDKL3_MOUSE Cyclin-dependent kinase-like 3 OS...3329e-24     110     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
834Q4R8T9    590   CDKL3_MACFA Cyclin-dependent kinase-like 3 OS...3329e-24     110     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
835Q9S7U9    363   M2K2_ARATH Mitogen-activated protein kinase k...2889e-24     107     24     48GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009631; P:cold acclimation; IMP:TAIR.::GO:0009814; P:defense response, incompatible interaction; IGI:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR.
836P38622    512   RCK1_YEAST Serine/threonine-protein kinase RC...3111e-23     109     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0040020; P:regulation of meiosis; IMP:SGD.
837Q52WX2    424   SBK1_HUMAN Serine/threonine-protein kinase SB...3401e-23     108     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
838Q6ZI44    365   SAPK6_ORYSJ Serine/threonine-protein kinase S...2791e-23     107     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
839Q8IVW4    592   CDKL3_HUMAN Cyclin-dependent kinase-like 3 OS...3321e-23     109     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
840Q9LZW4    442   CIPKE_ARATH CBL-interacting serine/threonine-...2811e-23     108     30     53GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
841O14408    382   KCC1_METAN Calcium/calmodulin-dependent prote...2971e-23     107     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
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