Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR490C
Length:
766
Number of sequences:
5887
Description:
YDR490C PKH1 SGDID:S000002898, Chr IV from 1434268-1431968, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
751Q9HBH9    465   MKNK2_HUMAN MAP kinase-interacting serine/thr...2866e-25     112     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0071243; P:cellular response to arsenic-containing substance; IDA:UniProtKB.::GO:0030097; P:hemopoiesis; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
752Q8CEE6    1383   PASK_MOUSE PAS domain-containing serine/threo...2896e-25     115     30     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0045719; P:negative regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; IMP:UniProtKB.::GO:0070092; P:regulation of glucagon secretion; IMP:UniProtKB.::GO:0043576; P:regulation of respiratory gaseous exchange; IMP:UniProtKB.
753Q5R8Z4    681   PAK6_PONAB Serine/threonine-protein kinase PA...2906e-25     114     25     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
754Q90XC2    697   NEK8_DANRE Serine/threonine-protein kinase Ne...2626e-25     114     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
755O13945    532   PPK9_SCHPO Protein kinase domain-containing p...2846e-25     113     28     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007165; P:signal transduction; NAS:PomBase.
756Q69ZM6    1316   STK36_MOUSE Serine/threonine-protein kinase 3...2706e-25     115     27     49GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.
GO:0042384; P:cilium assembly; IDA:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:UniProtKB.
757P11730    527   KCC2G_RAT Calcium/calmodulin-dependent protei...2736e-25     113     30     49GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:RGD.::GO:0001666; P:response to hypoxia; IDA:RGD.::GO:0006979; P:response to oxidative stress; IDA:RGD.
758O64812    339   SRK2J_ARATH Serine/threonine-protein kinase S...2807e-25     110     30     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
759P70507    575   GRK4_RAT G protein-coupled receptor kinase 4 ...2787e-25     113     29     50GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0050254; F:rhodopsin kinase activity; IDA:RGD.
GO:0002031; P:G-protein coupled receptor internalization; IMP:RGD.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
760Q99759    626   M3K3_HUMAN Mitogen-activated protein kinase k...2787e-25     114     29     49GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.
761Q9NQU5    681   PAK6_HUMAN Serine/threonine-protein kinase PA...2907e-25     114     25     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:UniProtKB.
762Q6Z8C8    459   CDKF4_ORYSJ Cyclin-dependent kinase F-4 OS=Or...3637e-25     112     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
763B7XHR6    595   KIN1_ENTBH Probable serine/threonine-protein ...2677e-25     113     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
764Q66I46    466   MKNK2_XENTR MAP kinase-interacting serine/thr...2878e-25     112     30     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
765Q9M9V8    545   CDPKA_ARATH Calcium-dependent protein kinase ...2938e-25     112     30     46GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.
766Q8SR90    309   Y8H9_ENCCU Probable cell division protein kin...2369e-25     110     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
767Q9HC98    313   NEK6_HUMAN Serine/threonine-protein kinase Ne...2751e-24     110     28     48GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IDA:UniProtKB.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000772; P:regulation of cellular senescence; TAS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IDA:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB.
768P51954    1203   NEK1_MOUSE Serine/threonine-protein kinase Ne...2691e-24     114     29     51GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IMP:MGI.::GO:0010212; P:response to ionizing radiation; IMP:MGI.
769Q9XUJ7    722   DKF1_CAEEL Serine/threonine-protein kinase dk...2681e-24     113     30     50GO:0030424; C:axon; IDA:WormBase.::GO:0005938; C:cell cortex; IDA:WormBase.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0005624; C:membrane fraction; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005886; C:plasma membrane; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.
770Q6ZEZ5    585   NEK3_ORYSJ Serine/threonine-protein kinase Ne...2791e-24     112     32     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
771O97627    689   ARBK1_DIDMA Beta-adrenergic receptor kinase 1...3261e-24     113     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047696; F:beta-adrenergic receptor kinase activity; IEA:EC.::GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; ISS:UniProtKB.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
772Q6CSX2    831   ATG1_KLULA Serine/threonine-protein kinase AT...3301e-24     113     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
773Q00168    530   KCC2A_DROME Calcium/calmodulin-dependent prot...2721e-24     112     28     49GO:0030424; C:axon; IDA:FlyBase.::GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0030425; C:dendrite; IDA:FlyBase.::GO:0045211; C:postsynaptic membrane; IDA:FlyBase.::GO:0048786; C:presynaptic active zone; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; TAS:FlyBase.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:FlyBase.
GO:0007616; P:long-term memory; IMP:FlyBase.::GO:0008049; P:male courtship behavior; IMP:FlyBase.::GO:0007528; P:neuromuscular junction development; NAS:FlyBase.::GO:0051489; P:regulation of filopodium assembly; IMP:FlyBase.::GO:0060278; P:regulation of ovulation; IGI:FlyBase.::GO:0007268; P:synaptic transmission; IMP:FlyBase.
774O08875    433   DCLK1_RAT Serine/threonine-protein kinase DCL...2791e-24     110     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
775Q8C078    588   KKCC2_MOUSE Calcium/calmodulin-dependent prot...3281e-24     112     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
776P51136    467   GSK3_DICDI Glycogen synthase kinase-3 OS=Dict...3141e-24     111     26     48
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0031154; P:culmination involved in sorocarp development; IMP:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0030155; P:regulation of cell adhesion; TAS:dictyBase.::GO:0061118; P:regulation of positive chemotaxis to cAMP; IMP:dictyBase.::GO:0042306; P:regulation of protein import into nucleus; IMP:dictyBase.::GO:0007165; P:signal transduction; IMP:dictyBase.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:UniProtKB.
777Q9W0V1    836   PDPK1_DROME 3-phosphoinositide-dependent prot...1272e-24     112     42     62GO:0005829; C:cytosol; TAS:Reactome.::GO:0031594; C:neuromuscular junction; IDA:FlyBase.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.
GO:0006916; P:anti-apoptosis; IMP:FlyBase.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007292; P:female gamete generation; TAS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; NAS:FlyBase.::GO:0030307; P:positive regulation of cell growth; NAS:FlyBase.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0046620; P:regulation of organ growth; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0007548; P:sex differentiation; TAS:UniProtKB.::GO:0007283; P:spermatogenesis; TAS:UniProtKB.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase.
778Q1LUA6    3028   TRIO_DANRE Triple functional domain protein O...2572e-24     114     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
779Q54PX0    496   Y4251_DICDI Probable serine/threonine-protein...2792e-24     111     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
780Q8VCR8    613   MYLK2_MOUSE Myosin light chain kinase 2, skel...2732e-24     112     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0055007; P:cardiac muscle cell differentiation; IEP:UniProtKB.::GO:0007274; P:neuromuscular synaptic transmission; IMP:MGI.::GO:0014816; P:satellite cell differentiation; IMP:UniProtKB.::GO:0035914; P:skeletal muscle cell differentiation; IEP:UniProtKB.
781Q9ES70    313   NEK6_MOUSE Serine/threonine-protein kinase Ne...2842e-24     109     27     48GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.
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