Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR466W
Length:
898
Number of sequences:
5887
Description:
YDR466W PKH3 SGDID:S000002874, Chr IV from 1395121-1397817, Genome Release 64-1-1, Verified ORF, "Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 (PDK1) and yeast Pkh1p and Pkh2p, two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
991P43565    1770   RIM15_YEAST Serine/threonine-protein kinase R...1250.000000000002     75.5     30     52GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:SGD.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0001324; P:age-dependent response to oxidative stress involved in chronological cell aging; IMP:SGD.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0040020; P:regulation of meiosis; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
992Q8TFG6    1318   PPK18_SCHPO Serine/threonine-protein kinase p...1140.000000000003     74.3     33     55GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.::GO:0000156; F:two-component response regulator activity; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
993B1WAR9    890   GWL_XENTR Serine/threonine-protein kinase gre...1110.000000000004     73.9     33     54GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051721; F:protein phosphatase 2A binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0034048; P:negative regulation of protein phosphatase type 2A activity; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.
994Q6NTJ3    887   GWL_XENLA Serine/threonine-protein kinase gre...1110.000000000005     73.6     32     52GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051721; F:protein phosphatase 2A binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.::GO:0007067; P:mitosis; IMP:UniProtKB.::GO:0034048; P:negative regulation of protein phosphatase type 2A activity; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.
995Q552E9    1367   PKGA_DICDI Probable serine/threonine-protein ...1130.00000000001     72.4     31     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
996Q9V3I5    1207   JIL1_DROME Chromosomal serine/threonine-prote...2290.000000001     66.2     25     42GO:0000228; C:nuclear chromosome; IDA:UniProtKB.::GO:0005705; C:polytene chromosome interband; IDA:UniProtKB.::GO:0016456; C:X chromosome located dosage compensation complex, transcription activating; IPI:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0031936; P:negative regulation of chromatin silencing; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
997A2AAJ9    8891   OBSCN_MOUSE Obscurin OS=Mus musculus (Mouse)....2270.000000002     65.9     23     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
998Q5VST9    7968   OBSCN_HUMAN Obscurin OS=Homo sapiens (Human)....2270.00000001     63.2     23     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; ISS:BHF-UCL.::GO:0030018; C:Z disc; ISS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0008307; F:structural constituent of muscle; NAS:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
999Q8C050    863   KS6A5_MOUSE Ribosomal protein S6 kinase alpha...692.1     35.8     35     54GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0043990; P:histone H2A-S1 phosphorylation; ISS:UniProtKB.::GO:0043987; P:histone H3-S10 phosphorylation; ISS:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
1000Q753D9    726   PKH3_ASHGO Serine/threonine-protein kinase PK...227.6     33.9     68     86
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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