Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR460W
Length:
321
Number of sequences:
5887
Description:
YDR460W TFB3 SGDID:S000002868, Chr IV from 1383811-1384776, Genome Release 64-1-1, Verified ORF, "Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair; ring finger protein similar to mammalian CAK and TFIIH subunit"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q03290    321   TFB3_YEAST RNA polymerase II transcription fa...3210     654     100     100GO:0070985; C:TFIIK complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:InterPro.::GO:0006289; P:nucleotide-excision repair; IMP:SGD.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:SGD.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:SGD.
2Q6FMP4    330   TFB3_CANGA RNA polymerase II transcription fa...3171e-176     499     74     90GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q6CT73    318   TFB3_KLULA RNA polymerase II transcription fa...3214e-172     487     74     87GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q75D20    318   TFB3_ASHGO RNA polymerase II transcription fa...3213e-167     475     72     86GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q6BP96    340   TFB3_DEBHA RNA polymerase II transcription fa...3381e-85     268     43     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q6C7D0    346   TFB3_YARLI RNA polymerase II transcription fa...3197e-77     245     44     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7O94684    318   TFB3_SCHPO RNA polymerase II transcription fa...3047e-58     195     37     58GO:0005829; C:cytosol; IDA:PomBase.::GO:0005675; C:holo TFIIH complex; TAS:PomBase.::GO:0000112; C:nucleotide-excision repair factor 3 complex; ISS:PomBase.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:InterPro.::GO:0006289; P:nucleotide-excision repair; ISS:PomBase.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IGI:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; IC:PomBase.
8P51950    324   MAT1_MARGL CDK-activating kinase assembly fac...1881e-32     128     38     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
9P51948    309   MAT1_HUMAN CDK-activating kinase assembly fac...3184e-31     124     30     52GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005675; C:holo TFIIH complex; IDA:UniProtKB.
GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0006370; P:mRNA capping; TAS:Reactome.::GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0006461; P:protein complex assembly; TAS:ProtInc.::GO:0006468; P:protein phosphorylation; IDA:GOC.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.::GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.::GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
10P51949    309   MAT1_MOUSE CDK-activating kinase assembly fac...1351e-30     122     45     67GO:0005675; C:holo TFIIH complex; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007512; P:adult heart development; IMP:MGI.::GO:0006915; P:apoptotic process; IMP:MGI.::GO:0044236; P:multicellular organismal metabolic process; IMP:MGI.::GO:0050790; P:regulation of catalytic activity; IMP:MGI.::GO:0051592; P:response to calcium ion; IMP:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0021591; P:ventricular system development; IMP:MGI.
11P51951    309   MAT1_XENLA CDK-activating kinase assembly fac...3141e-30     122     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
12Q13049    653   TRI32_HUMAN E3 ubiquitin-protein ligase TRIM3...760.055     38.9     36     51GO:0005634; C:nucleus; ISS:BHF-UCL.
GO:0017022; F:myosin binding; ISS:BHF-UCL.::GO:0043621; F:protein self-association; IDA:UniProtKB.::GO:0003723; F:RNA binding; ISS:BHF-UCL.::GO:0030957; F:Tat protein binding; TAS:BHF-UCL.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0031369; F:translation initiation factor binding; ISS:BHF-UCL.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IDA:BHF-UCL.::GO:0048147; P:negative regulation of fibroblast proliferation; ISS:BHF-UCL.::GO:0045787; P:positive regulation of cell cycle; IDA:BHF-UCL.::GO:0030307; P:positive regulation of cell growth; IDA:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.::GO:0050769; P:positive regulation of neurogenesis; ISS:BHF-UCL.::GO:0045666; P:positive regulation of neuron differentiation; ISS:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; ISS:BHF-UCL.::GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0034612; P:response to tumor necrosis factor; ISS:BHF-UCL.::GO:0009411; P:response to UV; ISS:BHF-UCL.
13Q8CH72    655   TRI32_MOUSE E3 ubiquitin-protein ligase TRIM3...760.068     38.5     36     51GO:0005737; C:cytoplasm; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:MGI.
GO:0017022; F:myosin binding; IPI:MGI.::GO:0043621; F:protein self-association; ISS:BHF-UCL.::GO:0003723; F:RNA binding; IDA:BHF-UCL.::GO:0031369; F:translation initiation factor binding; IPI:MGI.::GO:0043130; F:ubiquitin binding; ISS:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045444; P:fat cell differentiation; IEP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.::GO:0048147; P:negative regulation of fibroblast proliferation; IEP:BHF-UCL.::GO:0045787; P:positive regulation of cell cycle; ISS:BHF-UCL.::GO:0030307; P:positive regulation of cell growth; ISS:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; ISS:BHF-UCL.::GO:0050769; P:positive regulation of neurogenesis; IDA:BHF-UCL.::GO:0045666; P:positive regulation of neuron differentiation; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; IDA:BHF-UCL.::GO:0045862; P:positive regulation of proteolysis; ISS:BHF-UCL.::GO:0000209; P:protein polyubiquitination; ISS:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0034612; P:response to tumor necrosis factor; IDA:BHF-UCL.::GO:0009411; P:response to UV; IDA:BHF-UCL.
14Q86T96    592   RN180_HUMAN E3 ubiquitin-protein ligase RNF18...710.17     37.4     31     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
15Q9FKW0    522   RNG1A_ARATH Putative E3 ubiquitin-protein lig...560.17     37.4     39     48GO:0035102; C:PRC1 complex; IPI:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001709; P:cell fate determination; IMP:UniProtKB.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010076; P:maintenance of floral meristem identity; IMP:UniProtKB.::GO:0010077; P:maintenance of inflorescence meristem identity; IMP:UniProtKB.::GO:0010492; P:maintenance of shoot apical meristem identity; IMP:UniProtKB.::GO:0045814; P:negative regulation of gene expression, epigenetic; IGI:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q7TNF8    1846   RIMB1_MOUSE Peripheral-type benzodiazepine re...1290.19     37.4     27     47GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
17A2R7P5    1201   NST1_ASPNC Stress response protein nst1 OS=As...1380.29     36.6     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
18Q11072    218   YT44_CAEEL Uncharacterized RING finger protei...570.32     35.8     32     53
GO:0008270; F:zinc ion binding; IEA:InterPro.
19Q0VF96    1302   CGNL1_HUMAN Cingulin-like protein 1 OS=Homo s...1620.64     35.8     27     47GO:0016459; C:myosin complex; IEA:InterPro.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0003774; F:motor activity; IEA:InterPro.
20O57971    305   ASGX_PYRHO Putative L-asparaginase OS=NBRC 10...460.71     35     41     59
GO:0004067; F:asparaginase activity; IEA:EC.::GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
21Q5RAK3    592   RN180_PONAB E3 ubiquitin-protein ligase RNF18...710.74     35.4     31     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
22Q6DEU9    1172   CTR9_XENTR RNA polymerase-associated protein ...1090.75     35.4     25     50GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0005488; F:binding; IEA:InterPro.
GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.::GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
23Q60YN5    828   BRE1_CAEBR E3 ubiquitin-protein ligase bre-1 ...430.76     35.4     35     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
24Q8U4E6    306   ASGX_PYRFU Putative L-asparaginase OS=Pyrococ...460.8     34.7     41     59
GO:0004067; F:asparaginase activity; IEA:EC.::GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
25A1SV88    419   HEM1_PSYIN Glutamyl-tRNA reductase OS=Psychro...1420.84     35     22     46
GO:0008883; F:glutamyl-tRNA reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
26Q3U827    592   RN180_MOUSE E3 ubiquitin-protein ligase RNF18...700.96     35     31     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031227; C:intrinsic to endoplasmic reticulum membrane; IDA:MGI.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.
GO:0031624; F:ubiquitin conjugating enzyme binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:MGI.
27P19474    475   RO52_HUMAN E3 ubiquitin-protein ligase TRIM21...431.1     34.7     35     53GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; IMP:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0070206; P:protein trimerization; IDA:UniProtKB.
28Q0WX00    460   RNG1B_ARATH Putative E3 ubiquitin-protein lig...561.1     34.7     36     48GO:0035102; C:PRC1 complex; IPI:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001709; P:cell fate determination; IMP:UniProtKB.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010076; P:maintenance of floral meristem identity; IMP:UniProtKB.::GO:0010077; P:maintenance of inflorescence meristem identity; IMP:UniProtKB.::GO:0010492; P:maintenance of shoot apical meristem identity; IMP:UniProtKB.::GO:0045814; P:negative regulation of gene expression, epigenetic; IGI:TAIR.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29P34537    837   BRE1_CAEEL E3 ubiquitin-protein ligase bre-1 ...431.1     34.7     35     51GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0006664; P:glycolipid metabolic process; IMP:UniProtKB.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
30Q9VMA7    1430   TGO1_DROME Transport and Golgi organization p...621.3     34.7     32     69GO:0070971; C:endoplasmic reticulum exit site; IDA:FlyBase.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007030; P:Golgi organization; IMP:FlyBase.::GO:0009306; P:protein secretion; IMP:UniProtKB.
31O60229    2985   KALRN_HUMAN Kalirin OS=Homo sapiens (Human). ...2221.5     34.7     21     44GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; ISS:HGNC.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
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