Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR457W
Length:
3268
Number of sequences:
5887
Description:
YDR457W TOM1 SGDID:S000002865, Chr IV from 1369790-1379596, Genome Release 64-1-1, Verified ORF, "E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q03280    3268   TOM1_YEAST E3 ubiquitin-protein ligase TOM1 O...32680     6721     100     100GO:0005730; C:nucleolus; IDA:SGD.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
GO:0000448; P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0007067; P:mitosis; IMP:SGD.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IMP:SGD.::GO:0006997; P:nucleus organization; IMP:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2Q756G2    3258   TOM1_ASHGO Probable E3 ubiquitin-protein liga...33220     3231     52     70GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
3O13834    3227   PTR1_SCHPO E3 ubiquitin-protein ligase ptr1 O...5721e-21     108     25     44GO:0005634; C:nucleus; IDA:PomBase.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
4Q9P4Z1    4026   TOM1_NEUCR E3 ubiquitin-protein ligase TOM1-l...960.000003     57     30     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
5Q7Z6Z7    4374   HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1...2200.14     42     23     40GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0006284; P:base-excision repair; IMP:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016574; P:histone ubiquitination; IDA:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
6Q7TMY8    4377   HUWE1_MOUSE E3 ubiquitin-protein ligase HUWE1...981.1     38.9     32     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016574; P:histone ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
7Q8H0T4    3658   UPL2_ARATH E3 ubiquitin-protein ligase UPL2 O...700.28     40.8     36     59GO:0005829; C:cytosol; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
8Q8GY23    3681   UPL1_ARATH E3 ubiquitin-protein ligase UPL1 O...720.2     41.6     39     53GO:0005829; C:cytosol; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
9P51593    322   HUWE1_RAT E3 ubiquitin-protein ligase HUWE1 O...3228e-114     372     55     73GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016574; P:histone ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
10A1D3C5    816   RSP5_NEOFI Probable E3 ubiquitin-protein liga...3547e-99     346     48     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
11Q4WTF3    813   RSP5_ASPFU Probable E3 ubiquitin-protein liga...3549e-99     346     48     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
12B0XQ72    813   RSP5_ASPFC Probable E3 ubiquitin-protein liga...3549e-99     346     48     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
13Q0CCL1    808   RSP5_ASPTN Probable E3 ubiquitin-protein liga...3549e-98     343     48     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
14A1CQG2    815   RSP5_ASPCL Probable E3 ubiquitin-protein liga...3544e-97     341     47     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
15Q5BDP1    821   RSP5_EMENI E3 ubiquitin-protein ligase RSP5 O...3543e-96     339     48     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
16A2QQ28    821   RSP5_ASPNC Probable E3 ubiquitin-protein liga...3543e-96     338     48     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:UniProtKB.
17B8N7E5    812   RSP5_ASPFN Probable E3 ubiquitin-protein liga...3546e-96     338     47     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
18O14326    786   PUB3_SCHPO E3 ubiquitin-protein ligase pub3 O...3911e-95     336     46     65GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
19Q2UBP1    816   RSP5_ASPOR Probable E3 ubiquitin-protein liga...3553e-94     333     47     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
20Q9VVI3    1007   NEDD4_DROME E3 ubiquitin-protein ligase Nedd-...3843e-94     337     46     63GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:FlyBase.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0016199; P:axon midline choice point recognition; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0007528; P:neuromuscular junction development; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0002092; P:positive regulation of receptor internalization; IMP:FlyBase.::GO:0051965; P:positive regulation of synapse assembly; IMP:FlyBase.::GO:0031623; P:receptor internalization; IMP:UniProtKB.
21Q92462    767   PUB1_SCHPO E3 ubiquitin-protein ligase pub1 O...3542e-92     326     47     68GO:0071944; C:cell periphery; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:PomBase.
GO:0060360; P:negative regulation of leucine import in response to ammonium ion; IMP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.::GO:0051453; P:regulation of intracellular pH; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.::GO:0034762; P:regulation of transmembrane transport; IMP:PomBase.
22P46934    1319   NEDD4_HUMAN E3 ubiquitin-protein ligase NEDD4...3837e-92     335     45     64GO:0016327; C:apicolateral plasma membrane; TAS:BHF-UCL.::GO:0005938; C:cell cortex; IDA:BHF-UCL.::GO:0000785; C:chromatin; IDA:BHF-UCL.::GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0000151; C:ubiquitin ligase complex; ISS:BHF-UCL.
GO:0031698; F:beta-2 adrenergic receptor binding; IDA:UniProtKB.::GO:0050815; F:phosphoserine binding; ISS:BHF-UCL.::GO:0050816; F:phosphothreonine binding; ISS:BHF-UCL.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0070063; F:RNA polymerase binding; IPI:BHF-UCL.::GO:0019871; F:sodium channel inhibitor activity; IDA:BHF-UCL.::GO:0043130; F:ubiquitin binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0044111; P:development involved in symbiotic interaction; IMP:UniProtKB.::GO:0042921; P:glucocorticoid receptor signaling pathway; IDA:BHF-UCL.::GO:0010766; P:negative regulation of sodium ion transport; IDA:UniProtKB.::GO:0010768; P:negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; IMP:BHF-UCL.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; IEP:BHF-UCL.::GO:0046824; P:positive regulation of nucleocytoplasmic transport; IDA:BHF-UCL.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0050847; P:progesterone receptor signaling pathway; IDA:BHF-UCL.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0006622; P:protein targeting to lysosome; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0032801; P:receptor catabolic process; IDA:UniProtKB.::GO:0031623; P:receptor internalization; IDA:UniProtKB.::GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.::GO:0051592; P:response to calcium ion; TAS:BHF-UCL.::GO:0019089; P:transmission of virus; IMP:BHF-UCL.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:BHF-UCL.
23Q2TAS2    751   SMUF2_XENLA E3 ubiquitin-protein ligase SMURF...3692e-91     323     47     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
24Q5RBF2    959   NED4L_PONAB E3 ubiquitin-protein ligase NEDD4...3831e-90     325     44     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
25Q8CFI0    1004   NED4L_MOUSE E3 ubiquitin-protein ligase NEDD4...3831e-90     326     44     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
26Q96PU5    975   NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4...3832e-90     325     44     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0006883; P:cellular sodium ion homeostasis; NAS:UniProtKB.::GO:0007588; P:excretion; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0045807; P:positive regulation of endocytosis; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0042176; P:regulation of protein catabolic process; NAS:UniProtKB.::GO:0010038; P:response to metal ion; IDA:UniProtKB.::GO:0006814; P:sodium ion transport; NAS:UniProtKB.::GO:0030104; P:water homeostasis; NAS:UniProtKB.
27A9JRZ0    765   SMUF2_DANRE E3 ubiquitin-protein ligase SMURF...3492e-90     320     46     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
28P46935    887   NEDD4_MOUSE E3 ubiquitin-protein ligase NEDD4...4202e-90     323     42     62GO:0005829; C:cytosol; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IPI:MGI.
GO:0050815; F:phosphoserine binding; IDA:BHF-UCL.::GO:0050816; F:phosphothreonine binding; IDA:BHF-UCL.::GO:0070064; F:proline-rich region binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.
GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:UniProtKB.
29P39940    809   RSP5_YEAST E3 ubiquitin-protein ligase RSP5 O...3548e-90     319     44     68GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0010008; C:endosome membrane; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0005794; C:Golgi apparatus; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0000151; C:ubiquitin ligase complex; IDA:MGI.
GO:0035091; F:phosphatidylinositol binding; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.
GO:0034644; P:cellular response to UV; IMP:SGD.::GO:0006333; P:chromatin assembly or disassembly; IMP:SGD.::GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IMP:SGD.::GO:0007005; P:mitochondrion organization; IMP:SGD.::GO:0045723; P:positive regulation of fatty acid biosynthetic process; IMP:SGD.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IPI:SGD.::GO:0006513; P:protein monoubiquitination; IMP:SGD.::GO:0000209; P:protein polyubiquitination; IMP:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0032956; P:regulation of actin cytoskeleton organization; IGI:SGD.::GO:0010794; P:regulation of dolichol biosynthetic process; IMP:SGD.::GO:0032443; P:regulation of ergosterol biosynthetic process; IMP:SGD.::GO:0010793; P:regulation of mRNA export from nucleus; IMP:SGD.::GO:0010796; P:regulation of multivesicular body size; IMP:SGD.::GO:0006808; P:regulation of nitrogen utilization; IGI:SGD.::GO:0019220; P:regulation of phosphate metabolic process; IGI:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:2000203; P:regulation of ribosomal large subunit export from nucleus; IMP:SGD.::GO:2000232; P:regulation of rRNA processing; IMP:SGD.::GO:2000238; P:regulation of tRNA export from nucleus; IMP:SGD.::GO:2000235; P:regulation of tRNA processing; IMP:SGD.::GO:0010795; P:regulation of ubiquinone biosynthetic process; IMP:SGD.::GO:0042493; P:response to drug; IMP:SGD.::GO:0034517; P:ribophagy; IGI:SGD.::GO:0070086; P:ubiquitin-dependent endocytosis; IMP:SGD.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
30A2A5Z6    748   SMUF2_MOUSE E3 ubiquitin-protein ligase SMURF...3605e-89     315     46     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
31F8W2M1    904   HACE1_DANRE E3 ubiquitin-protein ligase HACE1...4371e-88     318     40     60GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
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