Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR457W
Length:
3268
Number of sequences:
5887
Description:
YDR457W TOM1 SGDID:S000002865, Chr IV from 1369790-1379596, Genome Release 64-1-1, Verified ORF, "E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q8SSY6    1887   SPKUL_DICDI Bifunctional serine/threonine-pro...540.002     48.1     41     63GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
92P33202    1483   UFD4_YEAST Ubiquitin fusion degradation prote...3682e-21     107     27     43GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
93Q9VR91    4912   HERC2_DROME Probable E3 ubiquitin-protein lig...3302e-18     97.4     25     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
94Q10435    1647   YDE1_SCHPO Probable ubiquitin fusion degradat...3826e-16     89.4     26     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
95Q62671    2788   UBR5_RAT E3 ubiquitin-protein ligase UBR5 OS=...2977e-16     89     25     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
96O95071    2799   UBR5_HUMAN E3 ubiquitin-protein ligase UBR5 O...2979e-16     89     25     45GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0035413; P:positive regulation of catenin import into nucleus; IMP:BHF-UCL.::GO:0033160; P:positive regulation of protein import into nucleus, translocation; IMP:BHF-UCL.::GO:0050847; P:progesterone receptor signaling pathway; IDA:HGNC.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IDA:HGNC.
97Q80TP3    2792   UBR5_MOUSE E3 ubiquitin-protein ligase UBR5 O...2970.000000000000001     88.6     25     45GO:0005634; C:nucleus; ISS:HGNC.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0050847; P:progesterone receptor signaling pathway; ISS:HGNC.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; ISS:HGNC.
98Q6WWW4    1888   UPL3_ARATH E3 ubiquitin-protein ligase UPL3 O...4020.000000000000003     87     24     39GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0042023; P:DNA endoreduplication; IMP:TAIR.::GO:0006464; P:protein modification process; IEA:InterPro.::GO:0010091; P:trichome branching; IMP:TAIR.
99Q9ULT8    2610   HECD1_HUMAN E3 ubiquitin-protein ligase HECTD...1920.000000000002     77.8     28     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
100Q69ZR2    2618   HECD1_MOUSE E3 ubiquitin-protein ligase HECTD...1950.00000000004     73.6     28     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0001843; P:neural tube closure; IMP:UniProtKB.
101Q9Y4D8    3996   K0614_HUMAN Probable E3 ubiquitin-protein lig...2920.000000001     68.6     24     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
102C6KTB7    10287   ALTH1_PLAF7 Putative E3 ubiquitin-protein lig...2800.00001     55.5     25     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
103Q6UDG4    433   UL01_PSHV1 Uncharacterized protein UL-1 OS=(P...1051.3     38.1     33     50GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
104P14888    115   NIFW_AZOVI Nitrogenase-stabilizing/protective...1064.2     34.3     25     50
GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
105C1DH23    115   NIFW_AZOVD Nitrogenase-stabilizing/protective...1064.2     34.3     25     50
GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
106Q9HPC2    233   RS4E_HALSA 30S ribosomal protein S4e OS=(Halo...984.8     35.8     28     45GO:0005840; C:ribosome; IEA:UniProtKB-KW.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
107B0R668    233   RS4E_HALS3 30S ribosomal protein S4e OS=Halob...984.8     35.8     28     45GO:0005840; C:ribosome; IEA:UniProtKB-KW.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
108Q6GGZ5    932   ODO1_STAAR 2-oxoglutarate dehydrogenase E1 co...2305.6     36.6     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
109Q931R8    932   ODO1_STAAM 2-oxoglutarate dehydrogenase E1 co...2305.6     36.6     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
110A5ISU5    932   ODO1_STAA9 2-oxoglutarate dehydrogenase E1 co...2305.6     36.6     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
111A6U1N4    932   ODO1_STAA2 2-oxoglutarate dehydrogenase E1 co...2305.6     36.6     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
112A7X295    932   ODO1_STAA1 2-oxoglutarate dehydrogenase E1 co...2305.6     36.6     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
113A8Z3Z0    932   ODO1_STAAT 2-oxoglutarate dehydrogenase E1 co...2305.7     36.6     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
114Q6G9E8    932   ODO1_STAAS 2-oxoglutarate dehydrogenase E1 co...2305.7     36.6     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
115A6QGW6    932   ODO1_STAAE 2-oxoglutarate dehydrogenase E1 co...2305.7     36.6     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
116Q5HG06    932   ODO1_STAAC 2-oxoglutarate dehydrogenase E1 co...2305.7     36.6     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
117Q2FYM1    932   ODO1_STAA8 2-oxoglutarate dehydrogenase E1 co...2305.7     36.6     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
118Q2FH25    932   ODO1_STAA3 2-oxoglutarate dehydrogenase E1 co...2305.7     36.6     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
119Q2YY05    932   ODO1_STAAB 2-oxoglutarate dehydrogenase E1 co...2305.8     36.2     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
120Q8NWR6    932   ODO1_STAAW 2-oxoglutarate dehydrogenase E1 co...2306.1     36.2     23     42
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
121A2BID5    813   MELT_DANRE Ventricular zone-expressed PH doma...1227.3     36.2     29     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007420; P:brain development; IMP:ZFIN.::GO:0042471; P:ear morphogenesis; IMP:ZFIN.
records
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