Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR457W
Length:
3268
Number of sequences:
5887
Description:
YDR457W TOM1 SGDID:S000002865, Chr IV from 1369790-1379596, Genome Release 64-1-1, Verified ORF, "E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q8CDU6    774   HECD2_MOUSE Probable E3 ubiquitin-protein lig...3875e-53     206     33     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
62Q5RD78    776   HECD2_PONAB Probable E3 ubiquitin-protein lig...3876e-53     206     33     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
63Q05086    875   UBE3A_HUMAN Ubiquitin-protein ligase E3A OS=H...4123e-48     192     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007420; P:brain development; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
64Q15386    1083   UBE3C_HUMAN Ubiquitin-protein ligase E3C OS=H...4108e-47     189     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
65Q9SCQ2    1142   UPL7_ARATH E3 ubiquitin-protein ligase UPL7 O...4362e-46     188     30     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
66Q5PQN1    1057   HERC4_RAT Probable E3 ubiquitin-protein ligas...3634e-46     187     32     51GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
67Q80U95    1083   UBE3C_MOUSE Ubiquitin-protein ligase E3C OS=M...4108e-46     186     31     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
68Q1K9C4    1029   YFK7_SCHPO Probable E3 ubiquitin protein liga...3659e-46     186     32     51GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
69O08759    885   UBE3A_MOUSE Ubiquitin-protein ligase E3A OS=M...4122e-45     184     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
70Q6PAV2    1057   HERC4_MOUSE Probable E3 ubiquitin-protein lig...3634e-45     184     32     50GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:UniProtKB.
71Q5GLZ8    1057   HERC4_HUMAN Probable E3 ubiquitin-protein lig...3632e-42     174     32     51GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
72Q757T0    839   HUL4_ASHGO Probable E3 ubiquitin-protein liga...3739e-42     171     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
73P40985    892   HUL4_YEAST Probable E3 ubiquitin-protein liga...3812e-41     171     31     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
74O94275    807   MUG30_SCHPO Probable E3 ubiquitin-protein lig...4166e-40     165     29     48GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
75Q9SU29    873   UPL5_ARATH E3 ubiquitin-protein ligase UPL5 O...3448e-40     166     31     50GO:0005737; C:cytoplasm; IDA:TAIR.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0010150; P:leaf senescence; IMP:TAIR.::GO:0042542; P:response to hydrogen peroxide; IEP:UniProtKB.::GO:0009753; P:response to jasmonic acid stimulus; IEP:UniProtKB.
76Q15034    1050   HERC3_HUMAN Probable E3 ubiquitin-protein lig...3656e-38     160     32     51GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
77Q7Z3V4    1068   UBE3B_HUMAN Ubiquitin-protein ligase E3B OS=H...3871e-37     159     32     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
78P53119    910   HUL5_YEAST Probable E3 ubiquitin-protein liga...3601e-37     159     33     50GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0000502; C:proteasome complex; IDA:SGD.
GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:SGD.
GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0000209; P:protein polyubiquitination; IDA:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
79Q9ES34    1070   UBE3B_MOUSE Ubiquitin-protein ligase E3B OS=M...3871e-37     159     31     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
80Q08CZ0    1072   UBE3B_XENTR Ubiquitin-protein ligase E3B OS=X...3872e-37     159     31     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
81Q9UII4    1024   HERC5_HUMAN E3 ISG15--protein ligase HERC5 OS...5464e-37     158     28     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0042296; F:ISG15 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032020; P:ISG15-protein conjugation; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0050688; P:regulation of defense response to virus; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
82Q15751    4861   HERC1_HUMAN Probable E3 ubiquitin-protein lig...3303e-34     149     30     52GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; TAS:ProtInc.
GO:0006464; P:protein modification process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
83Q8IVU3    1022   HERC6_HUMAN Probable E3 ubiquitin-protein lig...3637e-29     131     30     49GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
84Q9LYZ7    1502   UPL4_ARATH E3 ubiquitin-protein ligase UPL4 O...4066e-28     128     27     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
85Q14669    1992   TRIPC_HUMAN Probable E3 ubiquitin-protein lig...4731e-25     121     27     44GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
86Q4U2R1    4836   HERC2_MOUSE E3 ubiquitin-protein ligase HERC2...3295e-24     116     28     46GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:MGI.
87O95714    4834   HERC2_HUMAN E3 ubiquitin-protein ligase HERC2...3298e-24     115     27     46GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
88P51592    2885   HYD_DROME E3 ubiquitin-protein ligase hyd OS=...3033e-23     113     29     47GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048749; P:compound eye development; NAS:FlyBase.::GO:0007455; P:eye-antennal disc morphogenesis; IMP:FlyBase.::GO:0008585; P:female gonad development; IMP:FlyBase.::GO:0007446; P:imaginal disc growth; IMP:FlyBase.::GO:0007112; P:male meiosis cytokinesis; IMP:FlyBase.::GO:0045879; P:negative regulation of smoothened signaling pathway; NAS:FlyBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0030162; P:regulation of proteolysis; NAS:FlyBase.::GO:0007289; P:spermatid nucleus differentiation; IMP:FlyBase.
89Q5T447    861   HECD3_HUMAN E3 ubiquitin-protein ligase HECTD...3212e-22     109     27     48GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
90Q3U487    861   HECD3_MOUSE E3 ubiquitin-protein ligase HECTD...3216e-22     108     27     48GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0019905; F:syntaxin binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
91Q8SSY6    1887   SPKUL_DICDI Bifunctional serine/threonine-pro...540.002     48.1     41     63GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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