Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR456W
Length:
633
Number of sequences:
5887
Description:
YDR456W NHX1 SGDID:S000002864, Chr IV from 1367485-1369386, Genome Release 64-1-1, Verified ORF, "Na+/H+ and K+/H+ exchanger, required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P19634    815   SL9A1_HUMAN Sodium/hydrogen exchanger 1 OS=Ho...4228e-38     153     29     53GO:0016021; C:integral to membrane; TAS:UniProtKB.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0006885; P:regulation of pH; TAS:UniProtKB.
32Q6AI14    798   SL9A4_HUMAN Sodium/hydrogen exchanger 4 OS=Ho...4511e-37     152     29     51GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
GO:0006885; P:regulation of pH; IEA:InterPro.
33Q8BUE1    797   SL9A4_MOUSE Sodium/hydrogen exchanger 4 OS=Mu...4493e-37     152     29     48GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
GO:0006885; P:regulation of pH; IEA:InterPro.
34P48762    818   SL9A1_PIG Sodium/hydrogen exchanger 1 OS=Sus ...4542e-36     149     29     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
GO:0006885; P:regulation of pH; IEA:InterPro.
35P23791    816   SL9A1_RABIT Sodium/hydrogen exchanger 1 OS=Or...4548e-36     147     29     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
36Q28036    817   SL9A1_BOVIN Sodium/hydrogen exchanger 1 OS=Bo...4211e-35     146     28     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
GO:0006885; P:regulation of pH; IEA:InterPro.
37Q14940    896   SL9A5_HUMAN Sodium/hydrogen exchanger 5 OS=Ho...3331e-34     144     32     51GO:0016021; C:integral to membrane; TAS:ProtInc.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0015385; F:sodium:hydrogen antiporter activity; TAS:ProtInc.
GO:0006885; P:regulation of pH; IEA:InterPro.
38Q9Z0X2    898   SL9A5_RAT Sodium/hydrogen exchanger 5 OS=Ratt...3322e-33     140     30     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015385; F:sodium:hydrogen antiporter activity; IDA:RGD.
GO:0006885; P:regulation of pH; IEA:InterPro.
39P48761    822   SL9A1_CRIGR Sodium/hydrogen exchanger 1 OS=Cr...4543e-33     139     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
GO:0006885; P:regulation of pH; IEA:InterPro.
40P35449    667   NHX9_CAEEL Probable Na(+)/H(+) antiporter nhx...4302e-28     124     25     47GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015385; F:sodium:hydrogen antiporter activity; NAS:UniProtKB.
GO:0006885; P:regulation of pH; IEA:InterPro.
41O16452    670   NHX3_CAEEL Probable Na(+)/H(+) antiporter nhx...3953e-27     120     27     48GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
GO:0006885; P:regulation of pH; IEA:InterPro.
42Q9LKW9    1146   NHX7_ARATH Sodium/hydrogen exchanger 7 OS=Ara...3960.000000000000005     82.8     24     46GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0010163; P:high-affinity potassium ion import; IMP:TAIR.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:TAIR.::GO:0042542; P:response to hydrogen peroxide; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0006814; P:sodium ion transport; IMP:TAIR.
43Q3YL57    756   NHX8_ARATH Sodium/hydrogen exchanger 8 OS=Ara...4030.000000000002     74.3     24     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0010348; F:lithium:hydrogen antiporter activity; IGI:TAIR.
GO:0010352; P:lithium ion export; IMP:TAIR.
44P32703    549   YJCE_ECOLI Uncharacterized Na(+)/H(+) exchang...3620.0000000009     65.1     23     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
45A7Z8R4    671   NHAK_BACA2 Sodium, potassium, lithium and rub...2130.000003     53.9     26     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
46Q4KJF1    580   CVRA_PSEF5 Cell volume regulation protein A h...3630.00001     52     23     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:InterPro.
47A4WBF0    577   CVRA_ENT38 Cell volume regulation protein A O...3630.00002     51.2     24     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:InterPro.
48Q48P74    580   CVRA_PSE14 Cell volume regulation protein A h...3600.00002     51.2     23     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:InterPro.
49Q87VB6    580   CVRA_PSESM Cell volume regulation protein A h...3600.00002     50.8     23     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:InterPro.
50C3LSD1    581   CVRA_VIBCM Cell volume regulation protein A h...3630.00003     50.8     25     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:InterPro.
51Q9KNM9    581   CVRA_VIBCH Cell volume regulation protein A h...3630.00003     50.8     25     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:InterPro.
52O32212    670   NHAK_BACSU Sodium, potassium, lithium and rub...2170.00003     50.4     25     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
53Q4ZZ50    580   CVRA_PSEU2 Cell volume regulation protein A h...3590.00004     50.4     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:InterPro.
54Q87KV8    581   CVRA_VIBPA Cell volume regulation protein A h...3650.0008     46.2     24     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:InterPro.
55A8FHE3    671   NHAK_BACP2 Sodium, potassium, lithium and rub...3560.002     44.7     22     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
56P65527    542   Y2309_MYCBO Uncharacterized Na(+)/H(+) exchan...3130.003     44.3     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
57P65526    542   Y2287_MYCTU Uncharacterized Na(+)/H(+) exchan...3130.003     44.3     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
58Q60362    426   NAH1_METJA Na(+)/H(+) antiporter 1 OS=JCM 100...2110.006     43.1     25     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
59B1J2K7    580   CVRA_PSEPW Cell volume regulation protein A h...3300.006     43.1     24     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:InterPro.
60A7MKD6    576   CVRA_CROS8 Cell volume regulation protein A O...3640.007     43.1     26     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006813; P:potassium ion transport; IEA:InterPro.
61Q58916    422   NAH2_METJA Probable Na(+)/H(+) antiporter 2 O...620.007     43.1     34     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
records
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