Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR454C
Length:
187
Number of sequences:
5887
Description:
YDR454C GUK1 SGDID:S000002862, Chr IV from 1366827-1366264, Genome Release 64-1-1, reverse complement, Verified ORF, "Guanylate kinase, converts GMP to GDP; required for growth and mannose outer chain elongation of cell wall N-linked glycoproteins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361Q62936    849   DLG3_RAT Disks large homolog 3 OS=Rattus norv...1844e-23     100     35     56GO:0043198; C:dendritic shaft; IDA:UniProtKB.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.
GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
362P70175    849   DLG3_MOUSE Disks large homolog 3 OS=Mus muscu...1844e-23     100     35     56GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
363Q15700    870   DLG2_HUMAN Disks large homolog 2 OS=Homo sapi...1914e-23     100     35     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:ProtInc.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0004385; F:guanylate kinase activity; TAS:ProtInc.
GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
364Q92796    817   DLG3_HUMAN Disks large homolog 3 OS=Homo sapi...1845e-23     100     35     56GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0004385; F:guanylate kinase activity; NAS:UniProtKB.::GO:0019902; F:phosphatase binding; IDA:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.::GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
365Q6P7F1    635   MPP4_MOUSE MAGUK p55 subfamily member 4 OS=Mu...1876e-23     99.8     29     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IDA:MGI.
GO:0035418; P:protein localization to synapse; IMP:MGI.
366Q62696    911   DLG1_RAT Disks large homolog 1 OS=Rattus norv...1917e-23     100     34     54GO:0009925; C:basal plasma membrane; IDA:RGD.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; TAS:UniProtKB.::GO:0045211; C:postsynaptic membrane; TAS:RGD.::GO:0042734; C:presynaptic membrane; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.::GO:0030315; C:T-tubule; IDA:RGD.
GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0007015; P:actin filament organization; ISS:UniProtKB.::GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0030866; P:cortical actin cytoskeleton organization; ISS:UniProtKB.::GO:0001935; P:endothelial cell proliferation; ISS:UniProtKB.::GO:0045930; P:negative regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0043268; P:positive regulation of potassium ion transport; IMP:RGD.::GO:0032880; P:regulation of protein localization; IMP:RGD.
367Q6R005    801   DLG4_DANRE Disks large homolog 4 OS=Danio rer...1841e-22     99.8     35     56GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB.
GO:0050808; P:synapse organization; NAS:UniProtKB.::GO:0007268; P:synaptic transmission; NAS:UniProtKB.
368Q91XM9    852   DLG2_MOUSE Disks large homolog 2 OS=Mus muscu...1911e-22     99.8     35     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0044224; C:juxtaparanode region of axon; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IDA:MGI.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0019233; P:sensory perception of pain; IMP:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI.
369Q96JB8    637   MPP4_HUMAN MAGUK p55 subfamily member 4 OS=Ho...1873e-22     97.8     30     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
370Q9WV34    552   MPP2_MOUSE MAGUK p55 subfamily member 2 OS=Mu...1832e-21     95.1     32     53
371O70589    926   CSKP_MOUSE Peripheral plasma membrane protein...1791e-20     94     28     51GO:0016323; C:basolateral plasma membrane; IDA:MGI.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0045202; C:synapse; IDA:MGI.::GO:0019717; C:synaptosome; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
372Q5PYH7    881   DLG2_DANRE Disks large homolog 2 OS=Danio rer...1991e-20     94     33     52
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0050808; P:synapse organization; NAS:UniProtKB.::GO:0007268; P:synaptic transmission; NAS:UniProtKB.
373Q14168    576   MPP2_HUMAN MAGUK p55 subfamily member 2 OS=Ho...1851e-20     93.2     30     53GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.
GO:0004385; F:guanylate kinase activity; TAS:ProtInc.
GO:0007165; P:signal transduction; TAS:ProtInc.
374O14936    926   CSKP_HUMAN Peripheral plasma membrane protein...1791e-20     93.6     28     51GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0060170; C:cilium membrane; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005652; C:nuclear lamina; IDA:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0005730; C:nucleolus; IDA:BHF-UCL.::GO:0042734; C:presynaptic membrane; ISS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004385; F:guanylate kinase activity; TAS:ProtInc.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0001953; P:negative regulation of cell-matrix adhesion; IMP:BHF-UCL.::GO:0090288; P:negative regulation of cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0010839; P:negative regulation of keratinocyte proliferation; IMP:BHF-UCL.::GO:0061045; P:negative regulation of wound healing; IMP:BHF-UCL.
375P54936    961   LIN2_CAEEL Protein lin-2 OS=Caenorhabditis el...1811e-20     93.6     28     54GO:0030054; C:cell junction; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0018991; P:oviposition; IMP:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0009791; P:post-embryonic development; IMP:WormBase.
376Q62915    909   CSKP_RAT Peripheral plasma membrane protein C...1794e-20     92.4     27     51GO:0060170; C:cilium membrane; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0042734; C:presynaptic membrane; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; TAS:RGD.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IMP:RGD.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0003713; F:transcription coactivator activity; TAS:RGD.
GO:0006886; P:intracellular protein transport; IMP:RGD.::GO:0006461; P:protein complex assembly; TAS:RGD.
377Q5ZJ00    468   EM55_CHICK 55 kDa erythrocyte membrane protei...1196e-19     87.8     38     58GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
378Q24210    898   CSKP_DROME Peripheral plasma membrane protein...1815e-18     86.3     28     51GO:0031594; C:neuromuscular junction; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0061174; C:type I terminal button; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:FlyBase.::GO:0042043; F:neurexin family protein binding; IPI:BHF-UCL.
GO:0007628; P:adult walking behavior; IMP:FlyBase.::GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0007163; P:establishment or maintenance of cell polarity; NAS:FlyBase.::GO:0040011; P:locomotion; IMP:BHF-UCL.::GO:0008049; P:male courtship behavior; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IMP:BHF-UCL.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IDA:FlyBase.::GO:2000331; P:regulation of terminal button organization; IMP:BHF-UCL.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; NAS:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:BHF-UCL.::GO:0016080; P:synaptic vesicle targeting; NAS:FlyBase.
379P49697    467   EM55_TAKRU 55 kDa erythrocyte membrane protei...1736e-17     82     27     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
380Q96M69    825   LRGUK_HUMAN Leucine-rich repeat and guanylate...1816e-17     82.8     27     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
381Q13368    585   MPP3_HUMAN MAGUK p55 subfamily member 3 OS=Ho...1821e-16     81.6     29     51GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0004385; F:guanylate kinase activity; TAS:ProtInc.
GO:0007165; P:signal transduction; TAS:ProtInc.
382Q01230    151   A57_VACCW Guanylate kinase homolog OS=WR)). G...1362e-16     77     30     58
GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
383P21074    151   A57_VACCC Guanylate kinase homolog OS=Vaccini...1364e-16     76.3     30     57
GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
384O88954    585   MPP3_RAT MAGUK p55 subfamily member 3 OS=Ratt...1897e-16     79.3     28     51
GO:0030165; F:PDZ domain binding; IPI:RGD.
385Q9D5S7    820   LRGUK_MOUSE Leucine-rich repeat and guanylate...1817e-16     79.7     25     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
386O88910    568   MPP3_MOUSE MAGUK p55 subfamily member 3 OS=Mu...1790.000000000000007     76.3     27     51
387A9CKM5    183   PHNN_AGRT5 Ribose 1,5-bisphosphate phosphokin...1510.000000005     56.2     31     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0033863; F:ribose 1,5-bisphosphate phosphokinase activity; IEA:EC.
388Q96QZ7    1491   MAGI1_HUMAN Membrane-associated guanylate kin...1160.000000007     58.2     32     45GO:0042995; C:cell projection; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0051393; F:alpha-actinin binding; IPI:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0006461; P:protein complex assembly; NAS:ProtInc.
389Q9JK71    1470   MAGI3_RAT Membrane-associated guanylate kinas...500.00000001     57.4     44     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
390Q9EQJ9    1476   MAGI3_MOUSE Membrane-associated guanylate kin...490.00000002     57     45     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005109; F:frizzled binding; IPI:MGI.
391Q5TCQ9    1506   MAGI3_HUMAN Membrane-associated guanylate kin...490.00000002     57     45     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004385; F:guanylate kinase activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
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