Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR451C
Length:
353
Number of sequences:
5887
Description:
YDR451C YHP1 SGDID:S000002859, Chr IV from 1362181-1361120, Genome Release 64-1-1, reverse complement, Verified ORF, "One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q04116    353   YHP1_YEAST Homeobox protein YHP1 OS=Saccharom...3530     725     100     100GO:0000790; C:nuclear chromatin; IDA:SGD.
GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IPI:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0060277; P:negative regulation of transcription involved in G1 phase of mitotic cell cycle; IGI:SGD.
2P34161    385   YOX1_YEAST Homeobox protein YOX1 OS=Saccharom...2612e-51     181     43     61GO:0000790; C:nuclear chromatin; IDA:SGD.
GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IMP:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0060277; P:negative regulation of transcription involved in G1 phase of mitotic cell cycle; IMP:SGD.
3Q54PU1    638   HBX10_DICDI Homeobox protein 10 OS=Dictyostel...570.00000006     58.2     44     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q99160    509   HOY1_YARLI Homeobox protein HOY1 OS=lipolytic...550.0000003     55.8     44     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
5Q9FFI0    718   HDG9_ARATH Homeobox-leucine zipper protein HD...800.000002     53.5     33     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:TAIR.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q9S9Z0    708   HDG10_ARATH Homeobox-leucine zipper protein H...880.000003     52.4     28     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7O42115    453   ARX_DANRE Aristaless-related homeobox protein...690.000004     52     36     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q9I9D5    334   RX1_ASTFA Retinal homeobox protein Rx1 OS=Ast...1180.000004     51.6     29     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9O35085    564   ARX_MOUSE Homeobox protein ARX OS=Mus musculu...720.000005     52     36     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0021846; P:cell proliferation in forebrain; IMP:MGI.::GO:0021853; P:cerebral cortex GABAergic interneuron migration; IMP:MGI.::GO:0021800; P:cerebral cortex tangential migration; IMP:MGI.::GO:0021831; P:embryonic olfactory bulb interneuron precursor migration; IMP:MGI.::GO:0021759; P:globus pallidus development; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0046622; P:positive regulation of organ growth; IMP:MGI.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q96QS3    562   ARX_HUMAN Homeobox protein ARX OS=Homo sapien...720.000005     52     36     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q7T103    449   P5F11_XENLA POU domain, class 5, transcriptio...1260.000005     51.6     25     48GO:0005667; C:transcription factor complex; IPI:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0046332; F:SMAD binding; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0007369; P:gastrulation; IMP:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; IMP:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; IMP:UniProtKB.::GO:0045605; P:negative regulation of epidermal cell differentiation; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0050767; P:regulation of neurogenesis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12A6YP92    566   ARX_RAT Homeobox protein ARX OS=Rattus norveg...720.000006     51.6     36     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13Q9LTK3    682   HDG7_ARATH Homeobox-leucine zipper protein HD...590.000006     51.6     37     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:TAIR.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q9I9A2    327   RX2_ORYLA Retinal homeobox protein Rx2 OS=Ory...770.000007     50.8     35     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15Q8N693    406   ESX1_HUMAN Homeobox protein ESX1 OS=Homo sapi...610.000008     50.8     38     64GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16O35750    237   SHOX2_RAT Short stature homeobox protein 2 OS...600.000008     50.1     40     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
17O15266    292   SHOX_HUMAN Short stature homeobox protein OS=...990.000009     50.4     32     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0001501; P:skeletal system development; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
18Q7Y0V7    872   ROC6_ORYSJ Homeobox-leucine zipper protein RO...760.000009     51.2     32     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19P09083    449   GSBN_DROME Protein gooseberry-neuro OS=Drosop...1200.00001     50.4     26     43GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007367; P:segment polarity determination; IEP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20P53770    273   DLX3_NOTVI Homeobox protein DLX-3 OS=Notophth...1620.00001     49.7     29     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
21Q9PVY0    228   RX1_CHICK Retinal homeobox protein Rx1 OS=Gal...1120.00001     49.3     29     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22P70390    331   SHOX2_MOUSE Short stature homeobox protein 2 ...600.00001     50.1     40     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0003209; P:cardiac atrium morphogenesis; IMP:MGI.::GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IMP:MGI.::GO:0002063; P:chondrocyte development; IMP:MGI.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:MGI.::GO:0030326; P:embryonic limb morphogenesis; IMP:MGI.::GO:0060272; P:embryonic skeletal joint morphogenesis; IMP:MGI.::GO:0003170; P:heart valve development; IMP:MGI.::GO:0060415; P:muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0050772; P:positive regulation of axonogenesis; IMP:BHF-UCL.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.::GO:0048743; P:positive regulation of skeletal muscle fiber development; IMP:BHF-UCL.::GO:0045880; P:positive regulation of smoothened signaling pathway; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:2000172; P:regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0032330; P:regulation of chondrocyte differentiation; IMP:MGI.
23O60902    331   SHOX2_HUMAN Short stature homeobox protein 2 ...600.00001     50.1     40     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0007507; P:heart development; TAS:ProtInc.::GO:0007399; P:nervous system development; TAS:ProtInc.::GO:0001501; P:skeletal system development; TAS:ProtInc.
24Q91284    274   DLX3_PLEWA Distal-less-like protein DLX-3 OS=...1620.00002     49.7     29     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
25Q06453    408   AL_DROME Homeobox protein aristaless OS=Droso...690.00002     50.1     35     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IPI:FlyBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0035015; P:elongation of arista core; IMP:FlyBase.::GO:0007480; P:imaginal disc-derived leg morphogenesis; IMP:FlyBase.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IEP:FlyBase.
26Q1KKZ5    284   HXABB_TAKRU Homeobox protein Hox-A11b OS=Taki...760.00002     49.7     36     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q01702    269   DLX3B_DANRE Homeobox protein Dlx3b OS=Danio r...1460.00002     49.3     29     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
28O42356    330   RX1_DANRE Retinal homeobox protein Rx1 OS=Dan...910.00002     49.7     32     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q64205    287   DLX3_MOUSE Homeobox protein DLX-3 OS=Mus musc...1060.00002     49.3     33     54GO:0005634; C:nucleus; IDA:MGI.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0001568; P:blood vessel development; IMP:MGI.::GO:0001890; P:placenta development; IMP:MGI.
30P53774    277   DLL2_XENLA Homeobox protein DLL-2 OS=Xenopus ...920.00002     49.3     33     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
31Q8SW18    227   HD10_ENCCU Homeobox protein HD-10 OS=Encephal...560.00002     48.5     39     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
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