Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR451C
Length:
353
Number of sequences:
5887
Description:
YDR451C YHP1 SGDID:S000002859, Chr IV from 1362181-1361120, Genome Release 64-1-1, reverse complement, Verified ORF, "One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
901P22361    628   HNF1A_MOUSE Hepatocyte nuclear factor 1-alpha...1440.48     36.2     26     44GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001750; C:photoreceptor outer segment; IGI:MGI.::GO:0045120; C:pronucleus; IDA:MGI.::GO:0005667; C:transcription factor complex; IPI:MGI.
GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0015721; P:bile acid and bile salt transport; IMP:MGI.::GO:0006699; P:bile acid biosynthetic process; IMP:MGI.::GO:0001824; P:blastocyst development; IMP:MGI.::GO:0045453; P:bone resorption; IGI:MGI.::GO:0008203; P:cholesterol metabolic process; IMP:MGI.::GO:0006338; P:chromatin remodeling; IMP:UniProtKB.::GO:0030326; P:embryonic limb morphogenesis; IGI:MGI.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0006633; P:fatty acid biosynthetic process; IMP:MGI.::GO:0015908; P:fatty acid transport; IMP:MGI.::GO:0042593; P:glucose homeostasis; IDA:UniProtKB.::GO:0046323; P:glucose import; IDA:UniProtKB.::GO:0006783; P:heme biosynthetic process; IMP:MGI.::GO:0030073; P:insulin secretion; IMP:MGI.::GO:0001889; P:liver development; IMP:MGI.::GO:0048341; P:paraxial mesoderm formation; IGI:MGI.::GO:0001890; P:placenta development; IGI:MGI.::GO:0008104; P:protein localization; IMP:MGI.::GO:0050796; P:regulation of insulin secretion; IMP:MGI.::GO:0030111; P:regulation of Wnt receptor signaling pathway; IGI:MGI.::GO:0035623; P:renal glucose absorption; IDA:UniProtKB.::GO:0048608; P:reproductive structure development; IMP:MGI.::GO:0009749; P:response to glucose stimulus; IMP:MGI.::GO:0006979; P:response to oxidative stress; IMP:MGI.::GO:0043691; P:reverse cholesterol transport; IMP:MGI.::GO:0060395; P:SMAD protein signal transduction; IDA:MGI.
902P0C7M4    288   RHF2B_HUMAN Rhox homeobox family member 2B OS...510.49     35.8     31     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
903B5DFK3    343   HXD9_RAT Homeobox protein Hox-D9 OS=Rattus no...570.49     35.8     33     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
904P52729    265   HME2A_XENLA Homeobox protein engrailed-2-A OS...700.49     35.4     33     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
905P20823    631   HNF1A_HUMAN Hepatocyte nuclear factor 1-alpha...1440.49     36.2     26     44GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0046983; F:protein dimerization activity; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0046323; P:glucose import; IMP:UniProtKB.::GO:0030073; P:insulin secretion; IMP:UniProtKB.::GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; IGI:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0035623; P:renal glucose absorption; IMP:UniProtKB.
906Q94165    256   HM34_CAEEL Homeobox protein ceh-34 OS=Caenorh...610.49     35.4     31     52GO:0005634; C:nucleus; IDA:WormBase.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
907P50476    388   HOX3_XENLA Homeobox protein XHOX-3 OS=Xenopus...590.49     35.8     27     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
908Q1KL16    287   HXAAA_TAKRU Homeobox protein Hox-A10a OS=Taki...310.5     35.4     39     77GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
909A6NHT5    357   HMX3_HUMAN Homeobox protein HMX3 OS=Homo sapi...730.51     35.8     30     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
910P61374    349   ISL1_RAT Insulin gene enhancer protein ISL-1 ...560.51     35.8     32     54GO:0005634; C:nucleus; IDA:RGD.
GO:0030331; F:estrogen receptor binding; IDA:BHF-UCL.::GO:0016922; F:ligand-dependent nuclear receptor binding; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031103; P:axon regeneration; IEP:RGD.::GO:0071385; P:cellular response to glucocorticoid stimulus; IEP:BHF-UCL.::GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IDA:BHF-UCL.::GO:0090074; P:negative regulation of protein homodimerization activity; IDA:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; IMP:RGD.
911P61372    349   ISL1_MOUSE Insulin gene enhancer protein ISL-...560.51     35.8     32     54GO:0005634; C:nucleus; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060413; P:atrial septum morphogenesis; IGI:BHF-UCL.::GO:0060913; P:cardiac cell fate determination; IMP:MGI.::GO:0060379; P:cardiac muscle cell myoblast differentiation; IMP:MGI.::GO:0003215; P:cardiac right ventricle morphogenesis; IGI:BHF-UCL.::GO:0003203; P:endocardial cushion morphogenesis; IGI:BHF-UCL.::GO:0060384; P:innervation; IMP:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:BHF-UCL.::GO:0045665; P:negative regulation of neuron differentiation; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0001755; P:neural crest cell migration; IGI:MGI.::GO:0003148; P:outflow tract septum morphogenesis; IGI:BHF-UCL.::GO:0031016; P:pancreas development; IMP:MGI.::GO:0048936; P:peripheral nervous system neuron axonogenesis; IMP:BHF-UCL.::GO:0060037; P:pharyngeal system development; IGI:BHF-UCL.::GO:0021983; P:pituitary gland development; IMP:MGI.::GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.::GO:0043388; P:positive regulation of DNA binding; IDA:MGI.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:MGI.::GO:0003266; P:regulation of secondary heart field cardioblast proliferation; IMP:MGI.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:MGI.::GO:0048880; P:sensory system development; IMP:BHF-UCL.::GO:0021520; P:spinal cord motor neuron cell fate specification; IGI:MGI.::GO:0021559; P:trigeminal nerve development; IMP:BHF-UCL.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IGI:BHF-UCL.::GO:0021524; P:visceral motor neuron differentiation; IGI:MGI.
912P61373    349   ISL1_MESAU Insulin gene enhancer protein ISL-...560.51     35.8     32     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
913P61371    349   ISL1_HUMAN Insulin gene enhancer protein ISL-...560.51     35.8     32     54GO:0005737; C:cytoplasm; NAS:BHF-UCL.::GO:0005634; C:nucleus; NAS:BHF-UCL.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0001158; F:enhancer sequence-specific DNA binding; IDA:BHF-UCL.::GO:0030331; F:estrogen receptor binding; ISS:BHF-UCL.::GO:0016922; F:ligand-dependent nuclear receptor binding; ISS:BHF-UCL.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060413; P:atrial septum morphogenesis; ISS:BHF-UCL.::GO:0060913; P:cardiac cell fate determination; IDA:BHF-UCL.::GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.::GO:0071385; P:cellular response to glucocorticoid stimulus; ISS:BHF-UCL.::GO:0003203; P:endocardial cushion morphogenesis; ISS:BHF-UCL.::GO:0060384; P:innervation; ISS:BHF-UCL.::GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; ISS:BHF-UCL.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.::GO:0090074; P:negative regulation of protein homodimerization activity; ISS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0003148; P:outflow tract septum morphogenesis; ISS:BHF-UCL.::GO:0031016; P:pancreas development; ISS:BHF-UCL.::GO:0048936; P:peripheral nervous system neuron axonogenesis; ISS:BHF-UCL.::GO:0060037; P:pharyngeal system development; ISS:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; IC:BHF-UCL.::GO:0003139; P:secondary heart field specification; IMP:BHF-UCL.::GO:0048880; P:sensory system development; ISS:BHF-UCL.::GO:0021559; P:trigeminal nerve development; ISS:BHF-UCL.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
914P50211    349   ISL1_CHICK Insulin gene enhancer protein ISL-...560.51     35.8     32     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.
915Q00444    222   HXC5_HUMAN Homeobox protein Hox-C5 OS=Homo sa...570.51     35.4     35     56GO:0030054; C:cell junction; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
916P17278    235   HXD4_CHICK Homeobox protein Hox-D4 OS=Gallus ...360.51     35.4     42     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
917Q9BQY4    288   RHXF2_HUMAN Rhox homeobox family member 2 OS=...470.51     35.4     32     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
918Q6DGH9    315   OTBP_DANRE Homeobox protein orthopedia B OS=D...490.52     35.8     35     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
919P32043    222   HXC5_MOUSE Homeobox protein Hox-C5 OS=Mus mus...570.52     35.4     35     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
920Q08727    375   HXA2_CHICK Homeobox protein Hox-A2 OS=Gallus ...730.53     35.8     29     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
921Q8SWA6    167   HD11_ENCCU Homeobox protein HD-11 OS=Encephal...600.53     35     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
922P28356    352   HXD9_HUMAN Homeobox protein Hox-D9 OS=Homo sa...570.53     35.8     33     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
923A8XJD0    233   HM30_CAEBR Homeobox protein ceh-30 OS=Caenorh...630.54     35.4     25     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
924P42581    356   HMX3_MOUSE Homeobox protein HMX3 OS=Mus muscu...730.54     35.8     30     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007420; P:brain development; IGI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007566; P:embryo implantation; IMP:MGI.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0060135; P:maternal process involved in female pregnancy; IMP:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
925Q6IR52    445   PBX2_XENLA Pre-B-cell leukemia transcription ...620.55     35.8     35     53GO:0005667; C:transcription factor complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
926Q90XP0    303   HMX3A_ORYLA Homeobox protein HMX3-A OS=Oryzia...730.56     35.4     30     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
927Q9ZU70    220   ATB21_ARATH Homeobox-leucine zipper protein A...1810.56     35     21     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
928P53410    319   ISL2_CHICK Insulin gene enhancer protein ISL-...560.56     35.4     32     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
929P31260    410   HXA10_HUMAN Homeobox protein Hox-A10 OS=Homo ...310.58     35.8     39     74GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0007283; P:spermatogenesis; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
930P31310    416   HXA10_MOUSE Homeobox protein Hox-A10 OS=Mus m...310.58     35.8     39     74GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
931P20271    351   HM14_CAEEL Homeobox protein ceh-14 OS=Caenorh...590.58     35.4     31     53GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0016048; P:detection of temperature stimulus; IMP:UniProtKB.::GO:0030182; P:neuron differentiation; IMP:UniProtKB.::GO:0040040; P:thermosensory behavior; IMP:WormBase.
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