Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR451C
Length:
353
Number of sequences:
5887
Description:
YDR451C YHP1 SGDID:S000002859, Chr IV from 1362181-1361120, Genome Release 64-1-1, reverse complement, Verified ORF, "One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
871P28361    249   MSX1_CHICK Homeobox protein MSX-1 OS=Gallus g...300.38     35.8     47     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030509; P:BMP signaling pathway; IDA:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
872O13074    288   HXB4A_TAKRU Homeobox protein Hox-B4a OS=Takif...380.39     35.8     37     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
873Q03828    476   EVX2_HUMAN Homeobox even-skipped homolog prot...590.39     36.2     27     54GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
874Q0VCS4    372   HXA2_BOVIN Homeobox protein Hox-A2 OS=Bos tau...730.39     36.2     29     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
875Q29013    478   PO2F2_PIG POU domain, class 2, transcription ...690.39     36.2     26     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
876O09113    325   OTP_MOUSE Homeobox protein orthopedia OS=Mus ...490.39     36.2     35     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0021879; P:forebrain neuron differentiation; IMP:MGI.::GO:0021979; P:hypothalamus cell differentiation; IMP:MGI.::GO:0021985; P:neurohypophysis development; IMP:MGI.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
877Q5XKR4    325   OTP_HUMAN Homeobox protein orthopedia OS=Homo...490.39     36.2     35     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
878Q19503    329   HM40_CAEEL Homeobox protein ceh-40 OS=Caenorh...610.39     36.2     41     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.
879Q05917    288   HME2_CHICK Homeobox protein engrailed-2 OS=Ga...420.4     35.8     38     64GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0007411; P:axon guidance; IDA:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IDA:UniProtKB.::GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
880O35984    430   PBX2_MOUSE Pre-B-cell leukemia transcription ...620.4     36.2     35     52GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0030326; P:embryonic limb morphogenesis; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0009954; P:proximal/distal pattern formation; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
881Q9PWL5    245   HXA4A_DANRE Homeobox protein Hox-A4a OS=Danio...380.4     35.8     39     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
882P46604    278   HAT22_ARATH Homeobox-leucine zipper protein H...620.4     35.8     29     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0009735; P:response to cytokinin stimulus; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
883P22809    382   BAGP_DROME Homeobox protein bagpipe OS=Drosop...650.4     36.2     31     57GO:0005634; C:nucleus; IC:UniProtKB.
GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IGI:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.
GO:0007507; P:heart development; NAS:FlyBase.::GO:0007501; P:mesodermal cell fate specification; TAS:FlyBase.::GO:0007494; P:midgut development; TAS:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0007522; P:visceral muscle development; NAS:FlyBase.
884Q9PWD6    289   HXA10_MORSA Homeobox protein Hox-A10 OS=Moron...310.41     35.8     39     77GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
885A9L937    377   HXA2_PAPAN Homeobox protein Hox-A2 OS=Papio a...730.41     36.2     26     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
886P28167    3005   ZFH2_DROME Zinc finger protein 2 OS=Drosophil...500.42     36.6     34     62GO:0005634; C:nucleus; IDA:FlyBase.
GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007399; P:nervous system development; IEP:FlyBase.
887Q9QZW9    404   MNX1_MOUSE Motor neuron and pancreas homeobox...610.42     36.2     33     54GO:0005634; C:nucleus; IDA:MGI.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0060539; P:diaphragm development; IMP:MGI.::GO:0021904; P:dorsal/ventral neural tube patterning; IDA:MGI.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0008045; P:motor axon guidance; IMP:MGI.::GO:0021675; P:nerve development; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0021520; P:spinal cord motor neuron cell fate specification; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
888P09086    479   PO2F2_HUMAN POU domain, class 2, transcriptio...690.42     36.2     26     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0006959; P:humoral immune response; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
889Q96A47    359   ISL2_HUMAN Insulin gene enhancer protein ISL-...560.42     36.2     32     54GO:0005634; C:nucleus; IC:BHF-UCL.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048935; P:peripheral nervous system neuron development; TAS:BHF-UCL.
890P50219    401   MNX1_HUMAN Motor neuron and pancreas homeobox...610.43     36.2     33     54GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0006959; P:humoral immune response; TAS:ProtInc.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
891O43364    376   HXA2_HUMAN Homeobox protein Hox-A2 OS=Homo sa...730.45     35.8     26     53GO:0005634; C:nucleus; IDA:HPA.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
892Q9CXV0    359   ISL2_MOUSE Insulin gene enhancer protein ISL-...560.46     35.8     32     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:MGI.::GO:0021520; P:spinal cord motor neuron cell fate specification; IGI:MGI.::GO:0021524; P:visceral motor neuron differentiation; IMP:MGI.
893P28357    339   HXD9_MOUSE Homeobox protein Hox-D9 OS=Mus mus...570.46     35.8     33     58GO:0005634; C:nucleus; IDA:MGI.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0008344; P:adult locomotory behavior; IGI:MGI.::GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0035115; P:embryonic forelimb morphogenesis; IMP:MGI.::GO:0048704; P:embryonic skeletal system morphogenesis; IGI:MGI.::GO:0035137; P:hindlimb morphogenesis; IGI:MGI.::GO:0048935; P:peripheral nervous system neuron development; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0009954; P:proximal/distal pattern formation; IMP:MGI.::GO:0007519; P:skeletal muscle tissue development; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
894P17483    251   HXB4_HUMAN Homeobox protein Hox-B4 OS=Homo sa...380.46     35.4     37     63GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
895P40425    430   PBX2_HUMAN Pre-B-cell leukemia transcription ...620.46     35.8     35     52
GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
896P56672    409   OTP_DROME Homeobox protein orthopedia OS=Dros...500.47     35.8     32     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
897P15257    628   HNF1A_RAT Hepatocyte nuclear factor 1-alpha O...1440.47     36.2     26     44
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:RGD.
898Q00196    463   PO2F2_MOUSE POU domain, class 2, transcriptio...690.47     35.8     26     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0019904; F:protein domain specific binding; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0048469; P:cell maturation; IMP:MGI.::GO:0002380; P:immunoglobulin secretion involved in immune response; IMP:MGI.::GO:0002335; P:mature B cell differentiation; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
899P20270    84   HM07_CAEEL Homeobox protein ceh-7 OS=Caenorha...690.47     33.5     28     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
900P51783    162   HXA9_CAVPO Homeobox protein Hox-A9 OS=Cavia p...610.48     35     33     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
901P22361    628   HNF1A_MOUSE Hepatocyte nuclear factor 1-alpha...1440.48     36.2     26     44GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001750; C:photoreceptor outer segment; IGI:MGI.::GO:0045120; C:pronucleus; IDA:MGI.::GO:0005667; C:transcription factor complex; IPI:MGI.
GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0015721; P:bile acid and bile salt transport; IMP:MGI.::GO:0006699; P:bile acid biosynthetic process; IMP:MGI.::GO:0001824; P:blastocyst development; IMP:MGI.::GO:0045453; P:bone resorption; IGI:MGI.::GO:0008203; P:cholesterol metabolic process; IMP:MGI.::GO:0006338; P:chromatin remodeling; IMP:UniProtKB.::GO:0030326; P:embryonic limb morphogenesis; IGI:MGI.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0006633; P:fatty acid biosynthetic process; IMP:MGI.::GO:0015908; P:fatty acid transport; IMP:MGI.::GO:0042593; P:glucose homeostasis; IDA:UniProtKB.::GO:0046323; P:glucose import; IDA:UniProtKB.::GO:0006783; P:heme biosynthetic process; IMP:MGI.::GO:0030073; P:insulin secretion; IMP:MGI.::GO:0001889; P:liver development; IMP:MGI.::GO:0048341; P:paraxial mesoderm formation; IGI:MGI.::GO:0001890; P:placenta development; IGI:MGI.::GO:0008104; P:protein localization; IMP:MGI.::GO:0050796; P:regulation of insulin secretion; IMP:MGI.::GO:0030111; P:regulation of Wnt receptor signaling pathway; IGI:MGI.::GO:0035623; P:renal glucose absorption; IDA:UniProtKB.::GO:0048608; P:reproductive structure development; IMP:MGI.::GO:0009749; P:response to glucose stimulus; IMP:MGI.::GO:0006979; P:response to oxidative stress; IMP:MGI.::GO:0043691; P:reverse cholesterol transport; IMP:MGI.::GO:0060395; P:SMAD protein signal transduction; IDA:MGI.
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