rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q04089 | 582 | DOT1_YEAST Histone-lysine N-methyltransferase... | 582 | 0 | 1203 | 100 | 100 | GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0031151; F:histone methyltransferase activity (H3-K79 specific); IDA:SGD.::GO:0031493; F:nucleosomal histone binding; IDA:SGD. | | | | | | | | | | GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0000077; P:DNA damage checkpoint; IMP:SGD.::GO:0070911; P:global genome nucleotide-excision repair; IMP:SGD.::GO:0000725; P:recombinational repair; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | Q6FNM5 | 652 | DOT1_CANGA Histone-lysine N-methyltransferase... | 622 | 2e-149 | 452 | 41 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q756E1 | 575 | DOT1_ASHGO Histone-lysine N-methyltransferase... | 527 | 8e-131 | 401 | 43 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q6CWV1 | 572 | DOT1_KLULA Histone-lysine N-methyltransferase... | 555 | 5e-124 | 384 | 41 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q6C4Y5 | 492 | DOT1_YARLI Histone-lysine N-methyltransferase... | 319 | 5e-66 | 229 | 37 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q4WVH4 | 502 | DOT1_ASPFU Histone-lysine N-methyltransferase... | 310 | 2e-50 | 186 | 33 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q2U696 | 335 | DOT1_ASPOR Histone-lysine N-methyltransferase... | 297 | 5e-50 | 181 | 33 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q1DKD8 | 499 | DOT1_COCIM Histone-lysine N-methyltransferase... | 254 | 2e-49 | 183 | 37 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | Q6BTC8 | 1172 | DOT1_DEBHA Histone-lysine N-methyltransferase... | 278 | 7e-49 | 187 | 41 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q5BH89 | 501 | DOT1_EMENI Histone-lysine N-methyltransferase... | 310 | 2e-47 | 177 | 32 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q7SB74 | 531 | DOT1_NEUCR Histone-lysine N-methyltransferase... | 266 | 2e-44 | 169 | 38 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | Q5A309 | 1343 | DOT1_CANAL Histone-lysine N-methyltransferase... | 277 | 5e-44 | 173 | 38 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | Q4IJP1 | 493 | DOT1_GIBZE Histone-lysine N-methyltransferase... | 254 | 1e-42 | 164 | 37 | 59 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q2H9L1 | 510 | DOT1_CHAGB Histone-lysine N-methyltransferase... | 260 | 4e-40 | 157 | 34 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q4P2W8 | 798 | DOT1_USTMA Histone-lysine N-methyltransferase... | 236 | 2e-33 | 139 | 32 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | P0CN14 | 644 | DOT1_CRYNJ Histone-lysine N-methyltransferase... | 316 | 5e-29 | 125 | 30 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | P0CN15 | 644 | DOT1_CRYNB Histone-lysine N-methyltransferase... | 317 | 6e-29 | 125 | 30 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q8TEK3 | 1739 | DOT1L_HUMAN Histone-lysine N-methyltransferas... | 297 | 2e-25 | 115 | 28 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0046425; P:regulation of JAK-STAT cascade; IDA:UniProtKB.::GO:2000677; P:regulation of transcription regulatory region DNA binding; IMP:UniProtKB. | 19 | Q8INR6 | 1848 | DOT1L_DROME Histone-lysine N-methyltransferas... | 292 | 3e-17 | 89.7 | 26 | 45 | GO:0035097; C:histone methyltransferase complex; IC:UniProtKB. | | | | | | | | | | GO:0031151; F:histone methyltransferase activity (H3-K79 specific); IMP:UniProtKB. | | | | | | | | | | GO:0006348; P:chromatin silencing at telomere; IMP:UniProtKB.::GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:UniProtKB. | 20 | Q55AX2 | 1845 | DOT1L_DICDI Histone-lysine N-methyltransferas... | 215 | 0.000000000001 | 75.1 | 26 | 46 | GO:0005634; C:nucleus; IDA:dictyBase. | | | | | | | | | | GO:0031151; F:histone methyltransferase activity (H3-K79 specific); IDA:dictyBase. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031156; P:regulation of sorocarp development; IMP:dictyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | Q2J1P2 | 448 | HGD_RHOP2 Homogentisate 1,2-dioxygenase OS=Rh... | 208 | 0.084 | 39.3 | 24 | 38 | | | | | | | | | | | GO:0004411; F:homogentisate 1,2-dioxygenase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006559; P:L-phenylalanine catabolic process; IEA:UniProtKB-KW.::GO:0006572; P:tyrosine catabolic process; IEA:UniProtKB-KW. | 22 | Q13CD3 | 448 | HGD_RHOPS Homogentisate 1,2-dioxygenase OS=Rh... | 186 | 0.13 | 38.9 | 25 | 41 | | | | | | | | | | | GO:0004411; F:homogentisate 1,2-dioxygenase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006559; P:L-phenylalanine catabolic process; IEA:UniProtKB-KW.::GO:0006572; P:tyrosine catabolic process; IEA:UniProtKB-KW. | 23 | A4XQT3 | 911 | SECA_PSEMY Protein translocase subunit SecA O... | 118 | 0.37 | 37.4 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017038; P:protein import; IEA:InterPro.::GO:0006605; P:protein targeting; IEA:InterPro. | 24 | Q861Y6 | 213 | NICN1_CANFA Nicolin-1 OS=Canis familiaris (Do... | 79 | 0.94 | 35.4 | 29 | 52 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 25 | Q8HY31 | 367 | DCUP_SHEEP Uroporphyrinogen decarboxylase OS=... | 62 | 3.2 | 34.3 | 29 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 26 | P13010 | 732 | XRCC5_HUMAN X-ray repair cross-complementing ... | 87 | 3.6 | 34.3 | 24 | 45 | GO:0005958; C:DNA-dependent protein kinase-DNA ligase 4 complex; IEA:InterPro.::GO:0043564; C:Ku70:Ku80 complex; IDA:UniProtKB.::GO:0000783; C:nuclear telomere cap complex; TAS:BHF-UCL.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc.::GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0042162; F:telomeric DNA binding; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL. | | | | | | | | | | GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:UniProtKB.::GO:0019059; P:initiation of viral infection; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0019047; P:provirus integration; TAS:Reactome.::GO:0000723; P:telomere maintenance; TAS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | Q9BSH3 | 213 | NICN1_HUMAN Nicolin-1 OS=Homo sapiens (Human)... | 79 | 4.5 | 33.1 | 29 | 51 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 28 | Q9SPU7 | 1123 | TERT_ARATH Telomerase reverse transcriptase O... | 45 | 6.7 | 33.5 | 40 | 51 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003721; F:telomeric template RNA reverse transcriptase activity; IEA:InterPro. | | | | | | | | | | GO:0050000; P:chromosome localization; IMP:TAIR.::GO:0007000; P:nucleolus organization; IMP:TAIR.::GO:0007004; P:telomere maintenance via telomerase; IMP:TAIR. | 29 | P38995 | 1004 | ATU2_YEAST Copper-transporting ATPase OS=Sacc... | 93 | 6.7 | 33.5 | 31 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0012510; C:trans-Golgi network transport vesicle membrane; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019829; F:cation-transporting ATPase activity; IDA:SGD.::GO:0005507; F:copper ion binding; IDA:SGD.::GO:0004008; F:copper-exporting ATPase activity; IEA:EC. | | | | | | | | | | GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0006879; P:cellular iron ion homeostasis; IMP:SGD. | 30 | Q64535 | 1451 | ATP7B_RAT Copper-transporting ATPase 2 OS=Rat... | 70 | 7.4 | 33.5 | 29 | 51 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005923; C:tight junction; IDA:RGD.::GO:0005802; C:trans-Golgi network; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005507; F:copper ion binding; IDA:RGD.::GO:0004008; F:copper-exporting ATPase activity; TAS:RGD.::GO:0008270; F:zinc ion binding; IDA:RGD. | | | | | | | | | | GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0010043; P:response to zinc ion; IEP:RGD. | 31 | Q9S7J8 | 1001 | HMA7_ARATH Copper-transporting ATPase RAN1 OS... | 64 | 7.4 | 33.5 | 28 | 53 | GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005507; F:copper ion binding; IEA:InterPro.::GO:0004008; F:copper-exporting ATPase activity; IEA:EC. | | | | | | | | | | GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0009873; P:ethylene mediated signaling pathway; TAS:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR. |