Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR430C
Length:
989
Number of sequences:
5887
Description:
YDR430C CYM1 SGDID:S000002838, Chr IV from 1328470-1325501, Genome Release 64-1-1, reverse complement, Verified ORF, "Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P05458    962   PTRA_ECOLI Protease 3 OS=Escherichia coli (st...2140.0002     48.9     26     42GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IDA:EcoCyc.
32P55679    512   Y4WA_RHISN Uncharacterized zinc protease y4wA...3370.0009     46.6     22     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
33O86835    459   Y5738_STRCO Uncharacterized zinc protease SCO...2900.017     42.4     21     38
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
34Q8Z418    962   PTRA_SALTI Protease 3 OS=Salmonella typhi. GN...1780.055     41.2     25     40GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
35Q8ZMB5    962   PTRA_SALTY Protease 3 OS=Salmonella typhimuri...1780.056     41.2     25     40GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
36Q1L673    422   VDRB_DANRE Vitamin D3 receptor B OS=Danio rer...1090.16     39.3     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0008434; F:vitamin D3 receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
37Q54JQ2    962   IDE_DICDI Insulin-degrading enzyme homolog OS...2410.23     39.3     22     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
38Q28037    426   VDR_BOVIN Vitamin D3 receptor OS=Bos taurus (...960.26     38.5     24     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
39Q8BHG1    1161   NRDC_MOUSE Nardilysin OS=Mus musculus (Mouse)...3430.51     38.1     21     40GO:0005739; C:mitochondrion; IDA:MGI.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
40P47245    1161   NRDC_RAT Nardilysin OS=Rattus norvegicus (Rat...3430.57     37.7     21     40
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
41P45181    926   PQQL_HAEIN Probable zinc protease pqqL OS=Hae...1990.59     37.7     24     37
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
42O14077    969   MU138_SCHPO Putative zinc protease mug138 OS=...1820.71     37.4     25     45GO:0005829; C:cytosol; IDA:PomBase.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0071432; P:peptide mating pheromone maturation involved in conjugation with cellular fusion; ISS:PomBase.::GO:0006508; P:proteolysis; ISS:PomBase.
43Q95MH5    427   VDR_SAGOE Vitamin D3 receptor OS=Saguinus oed...1030.98     36.6     24     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0008434; F:vitamin D3 receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
44O43847    1150   NRDC_HUMAN Nardilysin OS=Homo sapiens (Human)...871.3     36.6     30     45GO:0009986; C:cell surface; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.
GO:0048408; F:epidermal growth factor binding; TAS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0007528; P:neuromuscular junction development; TAS:ProtInc.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0006508; P:proteolysis; NAS:UniProtKB.::GO:0052548; P:regulation of endopeptidase activity; IDA:BHF-UCL.
45Q5R4H6    1152   NRDC_PONAB Nardilysin OS=Pongo abelii (Sumatr...871.4     36.6     30     45
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
46Q10040    856   YQA4_CAEEL Putative zinc protease C28F5.4 OS=...841.5     36.6     27     44
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
47O42392    451   VDR_CHICK Vitamin D3 receptor OS=Gallus gallu...1001.7     36.2     25     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0008434; F:vitamin D3 receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
48Q9PTN2    453   VDRA_DANRE Vitamin D3 receptor A OS=Danio rer...1081.8     35.8     25     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IPI:ZFIN.::GO:0005499; F:vitamin D binding; IDA:ZFIN.::GO:0008434; F:vitamin D3 receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
49Q24K02    1019   IDE_BOVIN Insulin-degrading enzyme OS=Bos tau...593.4     35.4     29     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
50P14735    1019   IDE_HUMAN Insulin-degrading enzyme OS=Homo sa...594.1     35     29     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; IDA:UniProtKB.::GO:0010815; P:bradykinin catabolic process; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
51A3RGC1    427   VDR_PIG Vitamin D3 receptor OS=Sus scrofa (Pi...1005.3     34.3     24     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0008434; F:vitamin D3 receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
52P35559    1019   IDE_RAT Insulin-degrading enzyme OS=Rattus no...596.4     34.3     29     54GO:0009986; C:cell surface; IDA:RGD.::GO:0031597; C:cytosolic proteasome complex; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005782; C:peroxisomal matrix; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016887; F:ATPase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IPI:RGD.::GO:0031626; F:beta-endorphin binding; IMP:RGD.::GO:0043559; F:insulin binding; IMP:RGD.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0042447; P:hormone catabolic process; IDA:RGD.::GO:0045861; P:negative regulation of proteolysis; IDA:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:RGD.
53Q9JHR7    1019   IDE_MOUSE Insulin-degrading enzyme OS=Mus mus...596.5     34.3     29     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004222; F:metalloendopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0010815; P:bradykinin catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
54P11473    427   VDR_HUMAN Vitamin D3 receptor OS=Homo sapiens...1036.8     33.9     24     43GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0046965; F:retinoid X receptor binding; IPI:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0008434; F:vitamin D3 receptor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000902; P:cell morphogenesis; IMP:UniProtKB.::GO:0046697; P:decidualization; IEP:BHF-UCL.::GO:0010839; P:negative regulation of keratinocyte proliferation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0010980; P:positive regulation of vitamin D 24-hydroxylase activity; IDA:BHF-UCL.::GO:0060558; P:regulation of calcidiol 1-monooxygenase activity; ISS:BHF-UCL.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
55Q5WVN3    323   LPXK_LEGPL Tetraacyldisaccharide 4'-kinase OS...1067     33.9     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009029; F:tetraacyldisaccharide 4'-kinase activity; IEA:EC.
GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
56Q07954    4544   LRP1_HUMAN Prolow-density lipoprotein recepto...627.4     34.3     31     50GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0034185; F:apolipoprotein binding; IPI:BHF-UCL.::GO:0034187; F:apolipoprotein E binding; IDA:UniProtKB.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0070325; F:lipoprotein particle receptor binding; IC:BHF-UCL.::GO:0042954; F:lipoprotein transporter activity; NAS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:BHF-UCL.::GO:0004872; F:receptor activity; TAS:ProtInc.
GO:0035909; P:aorta morphogenesis; ISS:BHF-UCL.::GO:0043277; P:apoptotic cell clearance; ISS:BHF-UCL.::GO:2000587; P:negative regulation of platelet-derived growth factor receptor-beta signaling pathway; ISS:BHF-UCL.::GO:0014912; P:negative regulation of smooth muscle cell migration; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:BHF-UCL.::GO:0010875; P:positive regulation of cholesterol efflux; ISS:BHF-UCL.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:BHF-UCL.::GO:0032429; P:regulation of phospholipase A2 activity; ISS:BHF-UCL.
57Q5X499    323   LPXK_LEGPA Tetraacyldisaccharide 4'-kinase OS...1067.6     33.9     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009029; F:tetraacyldisaccharide 4'-kinase activity; IEA:EC.
GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
58Q5ZUI0    323   LPXK_LEGPH Tetraacyldisaccharide 4'-kinase OS...1067.8     33.9     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009029; F:tetraacyldisaccharide 4'-kinase activity; IEA:EC.
GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
59A5ICX5    323   LPXK_LEGPC Tetraacyldisaccharide 4'-kinase OS...1067.8     33.9     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009029; F:tetraacyldisaccharide 4'-kinase activity; IEA:EC.
GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
60P48281    422   VDR_MOUSE Vitamin D3 receptor OS=Mus musculus...967.8     33.9     23     45
GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0050892; P:intestinal absorption; IMP:MGI.::GO:0007595; P:lactation; IMP:MGI.::GO:0060745; P:mammary gland branching involved in pregnancy; IMP:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060058; P:positive regulation of apoptotic process involved in mammary gland involution; IMP:MGI.::GO:0060558; P:regulation of calcidiol 1-monooxygenase activity; IMP:BHF-UCL.::GO:0001501; P:skeletal system development; IMP:MGI.
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