Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR416W
Length:
859
Number of sequences:
5887
Description:
YDR416W SYF1 SGDID:S000002824, Chr IV from 1298432-1301011, Genome Release 64-1-1, Verified ORF, "Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; null mutant has splicing defect and arrests in G2/M; homologs in human and C. elegans"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q04048    859   SYF1_YEAST Pre-mRNA-splicing factor SYF1 OS=S...8590     1773     100     100GO:0000974; C:Prp19 complex; IDA:SGD.::GO:0071006; C:U2-type catalytic step 1 spliceosome; IDA:SGD.::GO:0071007; C:U2-type catalytic step 2 spliceosome; IDA:SGD.::GO:0071008; C:U2-type post-mRNA release spliceosomal complex; IDA:SGD.::GO:0071004; C:U2-type prespliceosome; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000349; P:generation of catalytic spliceosome for first transesterification step; IDA:SGD.
2Q6FUJ7    835   SYF1_CANGA Pre-mRNA-splicing factor SYF1 OS=N...8642e-166     511     36     56GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
3Q75EF0    803   SYF1_ASHGO Pre-mRNA-splicing factor SYF1 OS=Y...8495e-150     468     33     55GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
4Q6CYA2    798   SYF1_KLULA Pre-mRNA-splicing factor SYF1 OS=1...8487e-119     386     31     52GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
5Q7SAK5    829   SYF1_NEUCR Pre-mRNA-splicing factor syf-1 OS=...8371e-70     254     26     45GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
6Q52DF3    832   SYF1_MAGO7 Pre-mRNA-splicing factor SYF1 OS=b...8483e-70     253     26     44GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
7Q4WVF4    839   SYF1_ASPFU Pre-mRNA-splicing factor syf1 OS=A...8314e-70     253     26     45GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
8Q5BH69    851   SYF1_EMENI Pre-mRNA-splicing factor syf1 OS=1...8527e-66     241     26     44GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
9Q9P7R9    790   SYF1_SCHPO Pre-mRNA-splicing factor cwf3 OS=S...8391e-62     231     24     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.::GO:0005681; C:spliceosomal complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IC:PomBase.
10Q54Z08    850   SYF1_DICDI Pre-mRNA-splicing factor SYF1 OS=D...8093e-61     227     24     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q6CAR6    736   SYF1_YARLI Pre-mRNA-splicing factor SYF1 OS=l...8464e-61     225     25     43GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
12Q6BQ23    850   SYF1_DEBHA Pre-mRNA-splicing factor SYF1 OS=0...9253e-59     221     24     43GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
13P0CO08    1031   SYF1_CRYNJ Pre-mRNA-splicing factor SYF1 OS=A...5311e-58     220     28     50GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
14P0CO09    1031   SYF1_CRYNB Pre-mRNA-splicing factor SYF1 OS=(...5311e-58     220     28     50GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
15Q4P7S1    1081   SYF1_USTMA Pre-mRNA-splicing factor SYF1 OS=U...5788e-58     218     28     48GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
16Q9DCD2    855   SYF1_MOUSE Pre-mRNA-splicing factor SYF1 OS=M...1412.6     35.4     21     39
GO:0005488; F:binding; IEA:InterPro.
GO:0001824; P:blastocyst development; IMP:MGI.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB.::GO:0006283; P:transcription-coupled nucleotide-excision repair; ISS:UniProtKB.
17Q9HCS7    855   SYF1_HUMAN Pre-mRNA-splicing factor SYF1 OS=H...1412.8     35.4     21     39GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IDA:UniProtKB.::GO:0006283; P:transcription-coupled nucleotide-excision repair; IDA:UniProtKB.
18Q99PK0    855   SYF1_RAT Pre-mRNA-splicing factor SYF1 OS=Rat...1412.6     35.4     21     39
GO:0005488; F:binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB.::GO:0006283; P:transcription-coupled nucleotide-excision repair; ISS:UniProtKB.
19Q54XP4    705   CRNL1_DICDI Crooked neck-like protein 1 OS=Di...1100.0001     49.3     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
GO:0003723; F:RNA binding; ISS:UniProtKB.
GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
20Q7SGD2    695   CLF1_NEUCR Pre-mRNA-splicing factor clf-1 OS=...3630.15     39.3     20     40GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
21Q5AED6    758   CLF1_CANAL Pre-mRNA-splicing factor CLF1 OS=C...2040.0002     48.5     29     50GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
22Q9HF03    724   CLF1_CRYNV Pre-mRNA-splicing factor CLF1 OS=g...2200.25     38.5     23     43GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
23P0CO10    726   CLF1_CRYNJ Pre-mRNA-splicing factor CLF1 OS=A...2200.26     38.5     23     43GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
24P0CO11    726   CLF1_CRYNB Pre-mRNA-splicing factor CLF1 OS=(...2200.26     38.5     23     43GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
25Q4WT84    676   CLF1_ASPFU Pre-mRNA-splicing factor clf1 OS=A...3140.054     40.8     21     39GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
26P63155    690   CRNL1_RAT Crooked neck-like protein 1 OS=Ratt...851.3     36.2     25     48
GO:0003723; F:RNA binding; ISS:UniProtKB.
GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
27P63154    690   CRNL1_MOUSE Crooked neck-like protein 1 OS=Mu...851.3     36.2     25     48GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
GO:0003723; F:RNA binding; ISS:UniProtKB.
GO:0000245; P:spliceosomal complex assembly; ISS:UniProtKB.
28Q6BSP7    714   CLF1_DEBHA Pre-mRNA-splicing factor CLF1 OS=0...3010.024     42     23     45GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
29Q527H0    691   CLF1_MAGO7 Pre-mRNA-splicing factor CLF1 OS=b...2731.4     36.2     19     39GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
30Q9BZJ0    848   CRNL1_HUMAN Crooked neck-like protein 1 OS=Ho...851.9     35.8     25     48GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IDA:UniProtKB.
GO:0000245; P:spliceosomal complex assembly; IDA:UniProtKB.
31P87312    674   CLF1_SCHPO Pre-mRNA-splicing factor cwf4 OS=S...2220.078     40.4     23     40GO:0005681; C:spliceosomal complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IC:PomBase.
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