rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q04195 | 904 | SIZ1_YEAST E3 SUMO-protein ligase SIZ1 OS=Sac... | 904 | 0 | 1842 | 100 | 100 | GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0000790; C:nuclear chromatin; IDA:SGD.::GO:0005940; C:septin ring; IDA:SGD. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007059; P:chromosome segregation; IMP:SGD.::GO:0016925; P:protein sumoylation; IMP:SGD. | 2 | Q12216 | 726 | SIZ2_YEAST E3 SUMO-protein ligase SIZ2 OS=Sac... | 484 | 2e-116 | 378 | 42 | 61 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000790; C:nuclear chromatin; IDA:SGD. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030261; P:chromosome condensation; TAS:SGD.::GO:0007059; P:chromosome segregation; IMP:SGD.::GO:0016925; P:protein sumoylation; IDA:SGD. | 3 | O94451 | 727 | PLI1_SCHPO E3 SUMO-protein ligase pli1 OS=Sch... | 446 | 2e-42 | 169 | 30 | 45 | GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030999; P:linear element assembly; IMP:PomBase.::GO:0016925; P:protein sumoylation; IMP:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0051983; P:regulation of chromosome segregation; IMP:PomBase.::GO:0000019; P:regulation of mitotic recombination; IMP:PomBase.::GO:0032204; P:regulation of telomere maintenance; IMP:PomBase. | 4 | Q9JM05 | 507 | PIAS4_MOUSE E3 SUMO-protein ligase PIAS4 OS=M... | 191 | 1e-21 | 103 | 30 | 51 | GO:0016363; C:nuclear matrix; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0019789; F:SUMO ligase activity; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:MGI.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; NAS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IDA:BHF-UCL.::GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 5 | Q8N2W9 | 510 | PIAS4_HUMAN E3 SUMO-protein ligase PIAS4 OS=H... | 191 | 2e-21 | 102 | 30 | 51 | GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019789; F:SUMO ligase activity; IDA:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 6 | Q6AZ28 | 572 | PIAS2_RAT E3 SUMO-protein ligase PIAS2 OS=Rat... | 140 | 4e-18 | 92.8 | 32 | 52 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035259; F:glucocorticoid receptor binding; IPI:RGD.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:RGD.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:MGI.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0007283; P:spermatogenesis; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q8C5D8 | 621 | PIAS2_MOUSE E3 SUMO-protein ligase PIAS2 OS=M... | 140 | 5e-18 | 92.4 | 32 | 52 | GO:0016604; C:nuclear body; IDA:MGI.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0019789; F:SUMO ligase activity; IDA:MGI.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0016925; P:protein sumoylation; IDA:MGI.::GO:0045667; P:regulation of osteoblast differentiation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | O75928 | 621 | PIAS2_HUMAN E3 SUMO-protein ligase PIAS2 OS=H... | 140 | 6e-18 | 92.4 | 32 | 52 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019789; F:SUMO ligase activity; IDA:BHF-UCL.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | O75925 | 651 | PIAS1_HUMAN E3 SUMO-protein ligase PIAS1 OS=H... | 190 | 4e-17 | 89.7 | 28 | 50 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0019789; F:SUMO ligase activity; IDA:BHF-UCL.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.::GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | O70260 | 628 | PIAS3_RAT E3 SUMO-protein ligase PIAS3 OS=Rat... | 150 | 2e-16 | 87.4 | 30 | 49 | GO:0030425; C:dendrite; IDA:RGD.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:RGD. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0015459; F:potassium channel regulator activity; IDA:RGD.::GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0047485; F:protein N-terminus binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010628; P:positive regulation of gene expression; IDA:RGD.::GO:0045838; P:positive regulation of membrane potential; IDA:RGD.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009725; P:response to hormone stimulus; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q9Y6X2 | 628 | PIAS3_HUMAN E3 SUMO-protein ligase PIAS3 OS=H... | 150 | 3e-16 | 87 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | O54714 | 628 | PIAS3_MOUSE E3 SUMO-protein ligase PIAS3 OS=M... | 150 | 3e-16 | 87 | 30 | 49 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0019789; F:SUMO ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | Q94361 | 793 | GEI17_CAEEL E3 SUMO-protein ligase gei-17 OS=... | 178 | 4e-16 | 86.7 | 28 | 52 | | | | | | | | | | | GO:0001085; F:RNA polymerase II transcription factor binding; IPI:WormBase.::GO:0019789; F:SUMO ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0016925; P:protein sumoylation; IDA:WormBase. | 14 | O88907 | 651 | PIAS1_MOUSE E3 SUMO-protein ligase PIAS1 OS=M... | 142 | 6e-16 | 85.9 | 30 | 53 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q9ULJ6 | 1067 | ZMIZ1_HUMAN Zinc finger MIZ domain-containing... | 112 | 0.00000000000008 | 79.7 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q6P1E1 | 1072 | ZMIZ1_MOUSE Zinc finger MIZ domain-containing... | 112 | 0.00000000000009 | 79.3 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q8NF64 | 920 | ZMIZ2_HUMAN Zinc finger MIZ domain-containing... | 112 | 0.0000000000008 | 76.3 | 30 | 54 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0043596; C:nuclear replication fork; IDA:UniProtKB. | | | | | | | | | | GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q8CIE2 | 920 | ZMIZ2_MOUSE Zinc finger MIZ domain-containing... | 112 | 0.000000000001 | 75.5 | 30 | 54 | GO:0043596; C:nuclear replication fork; ISS:UniProtKB. | | | | | | | | | | GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. | 19 | Q6L4L4 | 875 | SIZ1_ORYSJ E3 SUMO-protein ligase SIZ1 OS=Ory... | 452 | 0.00000000003 | 70.9 | 21 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 20 | Q6ASW7 | 813 | SIZ2_ORYSJ E3 SUMO-protein ligase SIZ2 OS=Ory... | 250 | 0.0000000005 | 67 | 22 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 21 | Q680Q4 | 884 | SIZ1_ARATH E3 SUMO-protein ligase SIZ1 OS=Ara... | 87 | 0.000000002 | 65.5 | 29 | 60 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0019789; F:SUMO ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IMP:TAIR.::GO:0016049; P:cell growth; IMP:TAIR.::GO:0016036; P:cellular response to phosphate starvation; IMP:TAIR.::GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010247; P:detection of phosphate ion; IDA:TAIR.::GO:0048589; P:developmental growth; IMP:UniProtKB.::GO:0009908; P:flower development; IEA:UniProtKB-KW.::GO:0010286; P:heat acclimation; IMP:UniProtKB.::GO:0009910; P:negative regulation of flower development; IMP:TAIR.::GO:0010113; P:negative regulation of systemic acquired resistance; IMP:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0009787; P:regulation of abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0040008; P:regulation of growth; IMP:TAIR.::GO:0090352; P:regulation of nitrate assimilation; IMP:TAIR.::GO:2000070; P:regulation of response to water deprivation; IMP:TAIR.::GO:0010337; P:regulation of salicylic acid metabolic process; IMP:TAIR.::GO:0050826; P:response to freezing; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:UniProtKB. | 22 | Q18DN4 | 9159 | HMU_HALWD Halomucin OS=Haloquadratum walsbyi ... | 106 | 2.6 | 35.8 | 29 | 54 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030246; F:carbohydrate binding; IEA:InterPro.::GO:0004180; F:carboxypeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IEA:InterPro. | 23 | P0C6U3 | 4471 | R1A_CVHN1 Replicase polyprotein 1a OS=Human c... | 183 | 1.4 | 36.6 | 19 | 42 | GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro. | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro. | 24 | P0C6X2 | 7182 | R1AB_CVHN1 Replicase polyprotein 1ab OS=Human... | 183 | 1.4 | 36.6 | 19 | 42 | GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro. | 25 | P0C6U5 | 4421 | R1A_CVHN5 Replicase polyprotein 1a OS=Human c... | 140 | 1.4 | 36.6 | 19 | 42 | GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro. | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro. | 26 | P0C6X4 | 7132 | R1AB_CVHN5 Replicase polyprotein 1ab OS=Human... | 140 | 1.4 | 36.6 | 19 | 42 | GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro. | 27 | P0C6U4 | 4441 | R1A_CVHN2 Replicase polyprotein 1a OS=Human c... | 139 | 1.5 | 36.6 | 19 | 45 | GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro. | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro. | 28 | P0C6X3 | 7152 | R1AB_CVHN2 Replicase polyprotein 1ab OS=Human... | 139 | 1.5 | 36.6 | 19 | 45 | GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro. | 29 | Q6J6J0 | 1863 | BRCA1_PONPY Breast cancer type 1 susceptibili... | 69 | 0.13 | 40 | 33 | 55 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB. | 30 | P38398 | 1863 | BRCA1_HUMAN Breast cancer type 1 susceptibili... | 69 | 0.14 | 39.7 | 33 | 55 | GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0008274; C:gamma-tubulin ring complex; NAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.::GO:0001726; C:ruffle; IDA:BHF-UCL. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0015631; F:tubulin binding; NAS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0071681; P:cellular response to indole-3-methanol; IDA:UniProtKB.::GO:0007059; P:chromosome segregation; IMP:UniProtKB.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; TAS:UniProtKB.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:MGI.::GO:0000724; P:double-strand break repair via homologous recombination; IDA:HGNC.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0046600; P:negative regulation of centriole replication; NAS:UniProtKB.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; IMP:UniProtKB.::GO:0051573; P:negative regulation of histone H3-K9 methylation; IDA:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0071158; P:positive regulation of cell cycle arrest; IDA:BHF-UCL.::GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IDA:BHF-UCL.::GO:2000617; P:positive regulation of histone H3-K9 acetylation; IDA:BHF-UCL.::GO:2000620; P:positive regulation of histone H4-K16 acetylation; IDA:BHF-UCL.::GO:0070512; P:positive regulation of histone H4-K20 methylation; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006301; P:postreplication repair; IDA:HGNC.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:2000145; P:regulation of cell motility; IDA:BHF-UCL.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:UniProtKB.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL. | 31 | Q6J6I9 | 1863 | BRCA1_MACMU Breast cancer type 1 susceptibili... | 69 | 0.14 | 39.7 | 33 | 55 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB. |