Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR399W
Length:
221
Number of sequences:
5887
Description:
YDR399W HPT1 SGDID:S000002807, Chr IV from 1270068-1270733, Genome Release 64-1-1, Verified ORF, "Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q04178    221   HPRT_YEAST Hypoxanthine-guanine phosphoribosy...2219e-165     461     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0052657; F:guanine phosphoribosyltransferase activity; IEA:EC.::GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0032263; P:GMP salvage; IDA:SGD.::GO:0032264; P:IMP salvage; IDA:SGD.::GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
2P47165    209   XPT1_YEAST Xanthine phosphoribosyltransferase...2161e-71     223     56     70GO:0005737; C:cytoplasm; IDA:SGD.
GO:0000310; F:xanthine phosphoribosyltransferase activity; IMP:SGD.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0032265; P:XMP salvage; IMP:SGD.
3O13917    206   YDWD_SCHPO Uncharacterized protein C23C11.13c...2055e-56     183     56     68GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0005634; C:nucleus; ISS:PomBase.
GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; ISS:PomBase.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0032261; P:purine nucleotide salvage; ISS:PomBase.
4B0CGJ6    165   XGPT_BRUSI Xanthine phosphoribosyltransferase...1210.011     38.9     29     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
5A6X0U5    165   XGPT_OCHA4 Xanthine phosphoribosyltransferase...1490.011     38.9     30     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
6Q8G0P3    165   XGPT_BRUSU Xanthine phosphoribosyltransferase...1210.043     37.4     28     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
7A9MB59    165   XGPT_BRUC2 Xanthine phosphoribosyltransferase...1210.043     37.4     28     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
8Q8YH64    170   XGPT_BRUME Xanthine phosphoribosyltransferase...1620.05     37     27     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
9Q2YQ27    170   XGPT_BRUA2 Xanthine phosphoribosyltransferase...1620.05     37     27     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
10Q3SQJ9    168   XGPT_NITWN Xanthine phosphoribosyltransferase...1270.16     35.4     27     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
11Q28PG8    172   XGPT_JANSC Xanthine phosphoribosyltransferase...1190.21     35.4     28     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
12Q11IP4    165   XGPT_MESSB Xanthine phosphoribosyltransferase...1430.35     34.7     27     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
13Q2K9D7    164   XGPT_RHIEC Xanthine phosphoribosyltransferase...1470.42     34.3     27     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
14Q1MHW9    164   XGPT_RHIL3 Xanthine phosphoribosyltransferase...1470.47     34.3     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
15P47959    218   HPRT_MERUN Hypoxanthine-guanine phosphoribosy...460.86     33.5     35     61GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0052657; F:guanine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0007610; P:behavior; ISS:UniProtKB.::GO:0046038; P:GMP catabolic process; ISS:UniProtKB.::GO:0006178; P:guanine salvage; ISS:UniProtKB.::GO:0043103; P:hypoxanthine salvage; ISS:UniProtKB.::GO:0046040; P:IMP metabolic process; ISS:UniProtKB.::GO:0045964; P:positive regulation of dopamine metabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006164; P:purine nucleotide biosynthetic process; ISS:UniProtKB.::GO:0006166; P:purine ribonucleoside salvage; ISS:UniProtKB.
16Q8UEM6    165   XGPT_AGRT5 Xanthine phosphoribosyltransferase...1471.8     32.3     27     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
17A6U9A2    165   XGPT_SINMW Xanthine phosphoribosyltransferase...1442.4     32     28     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
18Q2IV51    172   XGPT_RHOP2 Xanthine phosphoribosyltransferase...1113     32     26     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000310; F:xanthine phosphoribosyltransferase activity; IEA:EC.
GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
19A4II60    224   PRDC1_XENTR Phosphoribosyltransferase domain-...443.3     32     39     61GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006166; P:purine ribonucleoside salvage; IEA:InterPro.
20Q3SZ18    218   HPRT_BOVIN Hypoxanthine-guanine phosphoribosy...623.5     32     32     55GO:0005829; C:cytosol; IBA:RefGenome.
GO:0052657; F:guanine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0006168; P:adenine salvage; IBA:RefGenome.::GO:0021954; P:central nervous system neuron development; IBA:RefGenome.::GO:0021895; P:cerebral cortex neuron differentiation; IBA:RefGenome.::GO:0019835; P:cytolysis; IBA:RefGenome.::GO:0048813; P:dendrite morphogenesis; IBA:RefGenome.::GO:0046038; P:GMP catabolic process; ISS:UniProtKB.::GO:0032263; P:GMP salvage; IBA:RefGenome.::GO:0007625; P:grooming behavior; IBA:RefGenome.::GO:0006178; P:guanine salvage; ISS:UniProtKB.::GO:0043103; P:hypoxanthine salvage; ISS:UniProtKB.::GO:0032264; P:IMP salvage; IBA:RefGenome.::GO:0046651; P:lymphocyte proliferation; IBA:RefGenome.::GO:0045964; P:positive regulation of dopamine metabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006166; P:purine ribonucleoside salvage; ISS:UniProtKB.::GO:0001975; P:response to amphetamine; IBA:RefGenome.::GO:0021756; P:striatum development; IBA:RefGenome.
21Q92EQ6    273   IOLB_LISIN 5-deoxy-glucuronate isomerase OS=L...754.1     31.6     29     48
GO:0008880; F:glucuronate isomerase activity; IEA:InterPro.
GO:0006064; P:glucuronate catabolic process; IEA:InterPro.
22Q9W719    218   HPRT_CHICK Hypoxanthine-guanine phosphoribosy...464.4     31.6     35     59GO:0005694; C:chromosome; IDA:AgBase.::GO:0005829; C:cytosol; IBA:RefGenome.
GO:0052657; F:guanine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0002060; F:purine base binding; TAS:AgBase.
GO:0006168; P:adenine salvage; IBA:RefGenome.::GO:0021954; P:central nervous system neuron development; IBA:RefGenome.::GO:0021895; P:cerebral cortex neuron differentiation; IBA:RefGenome.::GO:0019835; P:cytolysis; IBA:RefGenome.::GO:0048813; P:dendrite morphogenesis; IBA:RefGenome.::GO:0046038; P:GMP catabolic process; ISS:UniProtKB.::GO:0032263; P:GMP salvage; IBA:RefGenome.::GO:0007625; P:grooming behavior; IBA:RefGenome.::GO:0006178; P:guanine salvage; ISS:UniProtKB.::GO:0043103; P:hypoxanthine salvage; ISS:UniProtKB.::GO:0032264; P:IMP salvage; IBA:RefGenome.::GO:0046651; P:lymphocyte proliferation; IBA:RefGenome.::GO:0045964; P:positive regulation of dopamine metabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006166; P:purine ribonucleoside salvage; ISS:UniProtKB.::GO:0001975; P:response to amphetamine; IBA:RefGenome.::GO:0021756; P:striatum development; IBA:RefGenome.
23B8DCT7    273   IOLB_LISMH 5-deoxy-glucuronate isomerase OS=L...754.7     31.6     29     48
GO:0008880; F:glucuronate isomerase activity; IEA:InterPro.
GO:0006064; P:glucuronate catabolic process; IEA:InterPro.
24Q45FY6    218   HPRT_PIG Hypoxanthine-guanine phosphoribosylt...464.7     31.6     33     59GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0052657; F:guanine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0007610; P:behavior; ISS:UniProtKB.::GO:0046038; P:GMP catabolic process; ISS:UniProtKB.::GO:0006178; P:guanine salvage; ISS:UniProtKB.::GO:0043103; P:hypoxanthine salvage; ISS:UniProtKB.::GO:0046040; P:IMP metabolic process; ISS:UniProtKB.::GO:0045964; P:positive regulation of dopamine metabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006164; P:purine nucleotide biosynthetic process; ISS:UniProtKB.::GO:0006166; P:purine ribonucleoside salvage; ISS:UniProtKB.
25Q2UA42    406   SLX1_ASPOR Structure-specific endonuclease su...985.6     31.6     23     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
26Q6WIT9    218   HPRT_CANFA Hypoxanthine-guanine phosphoribosy...626.5     30.8     32     55GO:0005829; C:cytosol; IBA:RefGenome.
GO:0052657; F:guanine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0006168; P:adenine salvage; IBA:RefGenome.::GO:0021954; P:central nervous system neuron development; IBA:RefGenome.::GO:0021895; P:cerebral cortex neuron differentiation; IBA:RefGenome.::GO:0019835; P:cytolysis; IBA:RefGenome.::GO:0048813; P:dendrite morphogenesis; IBA:RefGenome.::GO:0046038; P:GMP catabolic process; ISS:UniProtKB.::GO:0032263; P:GMP salvage; IBA:RefGenome.::GO:0007625; P:grooming behavior; IBA:RefGenome.::GO:0006178; P:guanine salvage; ISS:UniProtKB.::GO:0043103; P:hypoxanthine salvage; ISS:UniProtKB.::GO:0032264; P:IMP salvage; IBA:RefGenome.::GO:0046651; P:lymphocyte proliferation; IBA:RefGenome.::GO:0045964; P:positive regulation of dopamine metabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006166; P:purine ribonucleoside salvage; ISS:UniProtKB.::GO:0001975; P:response to amphetamine; IBA:RefGenome.::GO:0021756; P:striatum development; IBA:RefGenome.
27Q6LDD9    218   HPRT_MACFA Hypoxanthine-guanine phosphoribosy...628.1     30.8     32     53GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0052657; F:guanine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0007610; P:behavior; ISS:UniProtKB.::GO:0046038; P:GMP catabolic process; ISS:UniProtKB.::GO:0006178; P:guanine salvage; ISS:UniProtKB.::GO:0043103; P:hypoxanthine salvage; ISS:UniProtKB.::GO:0046040; P:IMP metabolic process; ISS:UniProtKB.::GO:0045964; P:positive regulation of dopamine metabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006164; P:purine nucleotide biosynthetic process; ISS:UniProtKB.::GO:0006166; P:purine ribonucleoside salvage; ISS:UniProtKB.
28P00492    218   HPRT_HUMAN Hypoxanthine-guanine phosphoribosy...628.1     30.8     32     53GO:0005829; C:cytosol; TAS:Reactome.
GO:0052657; F:guanine phosphoribosyltransferase activity; IDA:UniProtKB.::GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
GO:0006168; P:adenine salvage; IBA:RefGenome.::GO:0021954; P:central nervous system neuron development; IBA:RefGenome.::GO:0021895; P:cerebral cortex neuron differentiation; IBA:RefGenome.::GO:0019835; P:cytolysis; IBA:RefGenome.::GO:0048813; P:dendrite morphogenesis; IBA:RefGenome.::GO:0046038; P:GMP catabolic process; IDA:UniProtKB.::GO:0032263; P:GMP salvage; IBA:RefGenome.::GO:0007625; P:grooming behavior; IBA:RefGenome.::GO:0006178; P:guanine salvage; IDA:UniProtKB.::GO:0043103; P:hypoxanthine salvage; IDA:UniProtKB.::GO:0032264; P:IMP salvage; IBA:RefGenome.::GO:0046651; P:lymphocyte proliferation; IBA:RefGenome.::GO:0045964; P:positive regulation of dopamine metabolic process; IMP:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0006166; P:purine ribonucleoside salvage; IMP:UniProtKB.::GO:0001975; P:response to amphetamine; IBA:RefGenome.::GO:0021756; P:striatum development; IBA:RefGenome.
29A5A6I1    218   HPRT_PANTR Hypoxanthine-guanine phosphoribosy...628.3     30.8     32     53GO:0005829; C:cytosol; IBA:RefGenome.
GO:0052657; F:guanine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IBA:RefGenome.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006168; P:adenine salvage; IBA:RefGenome.::GO:0021954; P:central nervous system neuron development; IBA:RefGenome.::GO:0021895; P:cerebral cortex neuron differentiation; IBA:RefGenome.::GO:0019835; P:cytolysis; IBA:RefGenome.::GO:0048813; P:dendrite morphogenesis; IBA:RefGenome.::GO:0046038; P:GMP catabolic process; ISS:UniProtKB.::GO:0032263; P:GMP salvage; IBA:RefGenome.::GO:0007625; P:grooming behavior; IBA:RefGenome.::GO:0006178; P:guanine salvage; ISS:UniProtKB.::GO:0043103; P:hypoxanthine salvage; ISS:UniProtKB.::GO:0032264; P:IMP salvage; IBA:RefGenome.::GO:0046651; P:lymphocyte proliferation; IBA:RefGenome.::GO:0045964; P:positive regulation of dopamine metabolic process; IBA:RefGenome.::GO:0006166; P:purine ribonucleoside salvage; IBA:RefGenome.::GO:0001975; P:response to amphetamine; IBA:RefGenome.::GO:0021756; P:striatum development; IBA:RefGenome.
30Q6DCP3    224   PRDC1_XENLA Phosphoribosyltransferase domain-...448.7     30.8     36     61GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006166; P:purine ribonucleoside salvage; IEA:InterPro.
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