Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR390C
Length:
636
Number of sequences:
5887
Description:
YDR390C UBA2 SGDID:S000002798, Chr IV from 1256847-1254937, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of a heterodimeric nuclear SUMO activating enzyme (E1) with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P52488    636   UBA2_YEAST Ubiquitin-activating enzyme E1-lik...6360     1303     100     100GO:0031510; C:SUMO activating enzyme complex; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; IPI:SGD.
GO:0016925; P:protein sumoylation; IDA:SGD.
2O42939    628   UBA2_SCHPO Ubiquitin-activating enzyme E1-lik...6373e-125     390     39     57GO:0031510; C:SUMO activating enzyme complex; TAS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:PomBase.
GO:0016925; P:protein sumoylation; IGI:PomBase.
3Q9UBT2    640   SAE2_HUMAN SUMO-activating enzyme subunit 2 O...6461e-97     318     34     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008047; F:enzyme activator activity; TAS:ProtInc.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0019948; F:SUMO activating enzyme activity; IDA:UniProtKB.
GO:0016925; P:protein sumoylation; IDA:UniProtKB.
4Q9Z1F9    638   SAE2_MOUSE SUMO-activating enzyme subunit 2 O...6482e-96     315     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:MGI.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
5Q9NAN1    582   SAE2_CAEEL SUMO-activating enzyme subunit uba...5426e-92     302     35     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; IDA:WormBase.
GO:0009952; P:anterior/posterior pattern specification; IGI:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0016925; P:protein sumoylation; IDA:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
6Q28GH3    641   SAE2_XENTR SUMO-activating enzyme subunit 2 O...5361e-90     300     36     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
7Q7ZY60    641   SAE2B_XENLA SUMO-activating enzyme subunit 2-...5242e-90     300     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
8Q642Q1    641   SAE2A_XENLA SUMO-activating enzyme subunit 2-...5242e-90     300     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
9Q7SXG4    650   SAE2_DANRE SUMO-activating enzyme subunit 2 O...6538e-89     295     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:UniProtKB.
GO:0016925; P:protein sumoylation; ISS:UniProtKB.
10Q54L40    661   SAE2_DICDI SUMO-activating enzyme subunit 2 O...4666e-85     285     38     57GO:0031510; C:SUMO activating enzyme complex; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; ISS:dictyBase.
GO:0016925; P:protein sumoylation; ISS:dictyBase.
11Q9SJT1    700   SAE2_ARATH SUMO-activating enzyme subunit 2 O...4522e-82     280     38     54GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019948; F:SUMO activating enzyme activity; IDA:TAIR.
GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0016925; P:protein sumoylation; IDA:TAIR.
12Q7ZVX6    462   UBA3_DANRE NEDD8-activating enzyme E1 catalyt...1640.012     42.4     24     39
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0045116; P:protein neddylation; IEA:InterPro.
13Q8TBC4    463   UBA3_HUMAN NEDD8-activating enzyme E1 catalyt...1640.004     43.5     23     40GO:0005634; C:nucleus; IDA:LIFEdb.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
GO:0045116; P:protein neddylation; IEA:InterPro.::GO:0006508; P:proteolysis; TAS:ProtInc.
14Q5R4A0    463   UBA3_PONAB NEDD8-activating enzyme E1 catalyt...1640.003     44.3     23     40
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0045116; P:protein neddylation; IEA:InterPro.
15Q99MI7    462   UBA3_RAT NEDD8-activating enzyme E1 catalytic...1640.002     44.3     23     40
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IMP:RGD.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:RGD.::GO:0045116; P:protein neddylation; TAS:RGD.
16Q8C878    462   UBA3_MOUSE NEDD8-activating enzyme E1 catalyt...1640.003     44.3     23     40
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; TAS:MGI.
GO:0007113; P:endomitotic cell cycle; IMP:MGI.::GO:0045116; P:protein neddylation; IEA:InterPro.::GO:0051726; P:regulation of cell cycle; IMP:MGI.
17Q09765    444   UBA3_SCHPO NEDD8-activating enzyme E1 catalyt...730.062     40     30     59GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0045116; P:protein neddylation; TAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
18Q9V6U8    450   UBA3_DROME NEDD8-activating enzyme E1 catalyt...1882e-36     145     40     59GO:0043234; C:protein complex; IPI:FlyBase.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:FlyBase.::GO:0045116; P:protein neddylation; IDA:FlyBase.
19O65041    454   UBA3_ARATH NEDD8-activating enzyme E1 catalyt...640.0001     48.5     36     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; IDA:TAIR.::GO:0046982; F:protein heterodimerization activity; NAS:TAIR.
GO:0045116; P:protein neddylation; TAS:TAIR.
20O94609    1012   UBA1_SCHPO Ubiquitin-activating enzyme E1 1 O...790.004     43.9     23     51GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0006464; P:protein modification process; IEA:InterPro.
21P52495    1021   UBA1_CANAW Ubiquitin-activating enzyme E1 1 O...820.002     45.4     22     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
22Q54QG9    442   UBA3_DICDI NEDD8-activating enzyme E1 catalyt...550.003     43.9     42     62
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; ISS:dictyBase.
GO:0045116; P:protein neddylation; ISS:dictyBase.
23P22515    1024   UBA1_YEAST Ubiquitin-activating enzyme E1 1 O...710.005     43.5     39     59GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004839; F:ubiquitin activating enzyme activity; IDA:SGD.
GO:0016567; P:protein ubiquitination; IDA:SGD.
24Q19360    430   UBA3_CAEEL NEDD8-activating enzyme E1 catalyt...1100.009     42.7     28     54GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0045116; P:protein neddylation; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
25Q99344    299   UBA3_YEAST NEDD8-activating enzyme E1 catalyt...1993e-32     130     37     58GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0019781; F:NEDD8 activating enzyme activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0045116; P:protein neddylation; IDA:SGD.
26Q55C16    1017   UBA1_DICDI Ubiquitin-like modifier-activating...1440.002     45.1     23     49GO:0005813; C:centrosome; TAS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
27P22314    1058   UBA1_HUMAN Ubiquitin-like modifier-activating...800.0007     46.6     28     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006464; P:protein modification process; IEA:InterPro.
28Q02053    1058   UBA1_MOUSE Ubiquitin-like modifier-activating...1440.0004     47.4     22     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
29Q29504    1058   UBA1_RABIT Ubiquitin-like modifier-activating...800.0007     46.6     28     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
30Q5U300    1058   UBA1_RAT Ubiquitin-like modifier-activating e...800.002     45.1     28     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
31A3KMV5    1058   UBA1_BOVIN Ubiquitin-like modifier-activating...800.0007     46.6     28     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
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