Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR389W
Length:
654
Number of sequences:
5887
Description:
YDR389W SAC7 SGDID:S000002797, Chr IV from 1252537-1254501, Genome Release 64-1-1, Verified ORF, "GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q62796    647   RBP1_RAT RalA-binding protein 1 OS=Rattus nor...880.00009     49.3     32     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IMP:RGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007052; P:mitotic spindle organization; IDA:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IPI:RGD.
92O94988    1023   FA13A_HUMAN Protein FAM13A OS=Homo sapiens (H...1250.00009     49.3     31     49GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
93O14559    1287   RHG33_HUMAN Rho GTPase-activating protein 33 ...1250.0001     49.3     30     46
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
94Q86L99    1523   GACHH_DICDI Rho GTPase-activating protein gac...890.0001     49.3     34     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
95Q9VDS5    740   RG92B_DROME Rho GTPase-activating protein 92B...1470.0001     49.3     24     40GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
96A2RUV4    1935   RHG21_XENTR Rho GTPase-activating protein 21 ...850.0001     49.3     28     51GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
97Q5T5U3    1957   RHG21_HUMAN Rho GTPase-activating protein 21 ...850.0001     49.3     29     49GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051683; P:establishment of Golgi localization; IDA:BHF-UCL.::GO:0007030; P:Golgi organization; IMP:BHF-UCL.::GO:0051684; P:maintenance of Golgi location; IMP:BHF-UCL.::GO:0072384; P:organelle transport along microtubule; IMP:BHF-UCL.::GO:0007165; P:signal transduction; IEA:InterPro.
98Q7Z6I6    1101   RHG30_HUMAN Rho GTPase-activating protein 30 ...1150.0001     49.3     30     46GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
99Q68EM7    881   RHG17_HUMAN Rho GTPase-activating protein 17 ...1120.0001     48.9     29     41GO:0005829; C:cytosol; TAS:Reactome.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
100Q63358    1980   MYO9B_RAT Unconventional myosin-IXb OS=Rattus...840.0001     48.9     29     54GO:0005884; C:actin filament; IDA:RGD.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:RGD.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0001726; C:ruffle; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0051015; F:actin filament binding; IDA:RGD.::GO:0030898; F:actin-dependent ATPase activity; IDA:RGD.::GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0043008; F:ATP-dependent protein binding; IDA:RGD.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IDA:RGD.
GO:0007266; P:Rho protein signal transduction; IDA:RGD.
101Q71M21    1902   RH21B_XENLA Rho GTPase-activating protein 21-...850.0002     48.9     28     51GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
102Q640N3    1101   RHG30_MOUSE Rho GTPase-activating protein 30 ...1150.0002     48.9     29     46GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
103Q13459    2157   MYO9B_HUMAN Unconventional myosin-IXb OS=Homo...840.0002     48.9     29     54GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031941; C:filamentous actin; IDA:UniProtKB.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0043531; F:ADP binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
GO:0030048; P:actin filament-based movement; TAS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; IC:UniProtKB.
104Q80Y19    987   RHGBA_MOUSE Rho GTPase-activating protein 11A...1140.0002     48.5     32     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
105B9VTT2    1091   RHG07_CANFA Rho GTPase-activating protein 7 O...930.0002     48.5     29     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
106Q12979    859   ABR_HUMAN Active breakpoint cluster region-re...860.0002     48.1     29     55GO:0005829; C:cytosol; TAS:Reactome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
107A6QNS3    859   ABR_BOVIN Active breakpoint cluster region-re...860.0002     48.1     29     55
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
108Q6DFG0    1926   RH21A_XENLA Rho GTPase-activating protein 21-...850.0003     48.1     27     49GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
109Q5SSL4    859   ABR_MOUSE Active breakpoint cluster region-re...860.0003     47.8     29     55GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043314; P:negative regulation of neutrophil degranulation; IGI:MGI.::GO:0050885; P:neuromuscular process controlling balance; IGI:MGI.::GO:0050766; P:positive regulation of phagocytosis; IGI:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.
110Q86IG9    566   GACH_DICDI Rho GTPase-activating protein gacH...1120.0003     47.8     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
111Q86I31    885   GACFF_DICDI Rho GTPase-activating protein gac...1100.0003     47.8     26     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
112D2H9U0    547   RHG36_AILME Rho GTPase-activating protein 36 ...850.0003     47.4     34     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
113P0CAX5    802   OPHN1_RAT Oligophrenin-1 OS=Rattus norvegicus...890.0003     47.8     29     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
114Q2M1Z3    1444   RHG31_HUMAN Rho GTPase-activating protein 31 ...1160.0003     47.8     28     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
115Q9C0H5    1083   RHG39_HUMAN Rho GTPase-activating protein 39 ...1500.0004     47.4     29     44GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
116O75044    1071   FNBP2_HUMAN SLIT-ROBO Rho GTPase-activating p...732     35.4     27     53GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
117A7E300    1112   RHG07_BOVIN Rho GTPase-activating protein 7 O...840.0004     47.4     31     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
118Q91Z67    1071   FNBP2_MOUSE SLIT-ROBO Rho GTPase-activating p...733.3     34.7     27     53GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
119Q9NYF5    915   FA13B_HUMAN Protein FAM13B OS=Homo sapiens (H...1210.0004     47.4     30     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
120Q54F80    514   GACD_DICDI Rho GTPase-activating protein gacD...770.0005     47     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
121Q8K2H3    851   FA13B_MOUSE Protein FAM13B OS=Mus musculus (M...1210.0005     47     30     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
records
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