Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR389W
Length:
654
Number of sequences:
5887
Description:
YDR389W SAC7 SGDID:S000002797, Chr IV from 1252537-1254501, Genome Release 64-1-1, Verified ORF, "GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q6TLK4    869   RHG27_RAT Rho GTPase-activating protein 27 OS...1220.00001     52.4     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:HGNC.::GO:0017124; F:SH3 domain binding; IDA:HGNC.
GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:HGNC.::GO:0006898; P:receptor-mediated endocytosis; IMP:HGNC.::GO:0007165; P:signal transduction; IEA:InterPro.
62Q99J31    802   OPHN1_MOUSE Oligophrenin-1 OS=Mus musculus (M...890.00001     52     30     55GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0043195; C:terminal button; IDA:MGI.
GO:0003779; F:actin binding; IDA:MGI.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IMP:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IMP:MGI.::GO:0051966; P:regulation of synaptic transmission, glutamatergic; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0048488; P:synaptic vesicle endocytosis; IMP:MGI.
63Q9PT60    655   RBP1A_XENLA RalA-binding protein 1-A OS=Xenop...1130.00001     52     28     52GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0001702; P:gastrulation with mouth forming second; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB.
64Q6DFV3    1944   RHG21_MOUSE Rho GTPase-activating protein 21 ...2780.00001     52.4     23     38GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
65Q07960    439   RHG01_HUMAN Rho GTPase-activating protein 1 O...830.00001     51.6     37     58GO:0005829; C:cytosol; TAS:Reactome.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
66Q5FWK3    439   RHG01_MOUSE Rho GTPase-activating protein 1 O...830.00002     51.6     37     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.
GO:0030675; F:Rac GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
67P97393    1501   RHG05_MOUSE Rho GTPase-activating protein 5 O...810.00002     52     35     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0030335; P:positive regulation of cell migration; IMP:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.::GO:0008361; P:regulation of cell size; IMP:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
68Q5TG30    622   RHG40_HUMAN Rho GTPase-activating protein 40 ...1430.00002     51.6     28     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
69Q13017    1502   RHG05_HUMAN Rho GTPase-activating protein 5 O...810.00002     52     35     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
70A6NI28    874   RHG42_HUMAN Rho GTPase-activating protein 42 ...2440.00002     51.6     24     36GO:0005622; C:intracellular; IEA:InterPro.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
71Q63744    1091   RHG07_RAT Rho GTPase-activating protein 7 OS=...840.00003     51.2     32     57GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0043274; F:phospholipase binding; IPI:RGD.::GO:0005100; F:Rho GTPase activator activity; IDA:RGD.::GO:0017166; F:vinculin binding; IPI:RGD.
GO:0007202; P:activation of phospholipase C activity; IDA:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; NAS:RGD.
72P98171    946   RHG04_HUMAN Rho GTPase-activating protein 4 O...870.00003     50.8     33     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; TAS:ProtInc.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
73B2RQE8    841   RHG42_MOUSE Rho GTPase-activating protein 42 ...2440.00003     50.8     24     36GO:0005622; C:intracellular; IEA:InterPro.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
74Q54FG5    873   GACJJ_DICDI Rho GTPase-activating protein gac...1330.00004     50.4     25     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
75Q3E875    376   RGAP1_ARATH Uncharacterized Rho GTPase-activa...1430.00005     49.7     29     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
76Q80YF9    1305   RHG33_MOUSE Rho GTPase-activating protein 33 ...1250.00005     50.4     30     46GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
77Q5VT97    1194   SYDE2_HUMAN Rho GTPase-activating protein SYD...2470.00005     50.4     23     37GO:0005829; C:cytosol; TAS:Reactome.
GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
78Q54QF4    909   MGP4_DICDI Mental retardation GTPase activati...740.00005     50.1     35     57GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
79Q9DBZ9    737   SYDE1_MOUSE Rho GTPase-activating protein SYD...1120.00006     50.1     28     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
80Q55DK5    1337   MGP3_DICDI Mental retardation GTPase activati...1140.00006     50.1     32     50GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
81Q9WVM1    628   RGAP1_MOUSE Rac GTPase-activating protein 1 O...860.00006     50.1     31     53GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0097149; C:centralspindlin complex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.
GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; ISS:UniProtKB.::GO:0007108; P:cytokinesis, initiation of separation; ISS:UniProtKB.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007405; P:neuroblast proliferation; IEP:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
82Q62172    648   RBP1_MOUSE RalA-binding protein 1 OS=Mus musc...1150.00006     49.7     27     51GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; ISS:UniProtKB.
GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
83Q9VIS1    1843   CDGAP_DROME GTPase-activating protein CdGAPr ...1180.00006     50.1     30     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0031290; P:retinal ganglion cell axon guidance; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
84Q6ZM89    805   RHG42_DANRE Rho GTPase-activating protein 42 ...1110.00006     50.1     30     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
85A6X8Z5    1425   RHG31_MOUSE Rho GTPase-activating protein 31 ...1240.00006     50.1     28     44GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0030027; C:lamellipodium; IDA:MGI.
GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI.
GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
86P59281    1107   RHG39_MOUSE Rho GTPase-activating protein 39 ...1500.00006     50.1     29     45GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0007165; P:signal transduction; IEA:InterPro.
87Q9H0H5    632   RGAP1_HUMAN Rac GTPase-activating protein 1 O...860.00007     49.7     31     52GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0097149; C:centralspindlin complex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0051233; C:spindle midzone; IDA:UniProtKB.
GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.::GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.::GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:UniProtKB.::GO:0007108; P:cytokinesis, initiation of separation; IMP:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0007018; P:microtubule-based movement; TAS:Reactome.::GO:0007405; P:neuroblast proliferation; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007283; P:spermatogenesis; IEP:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; IDA:UniProtKB.::GO:0008272; P:sulfate transport; IDA:UniProtKB.
88Q99N37    858   RHG17_RAT Rho GTPase-activating protein 17 OS...870.00008     49.7     33     47GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005626; C:insoluble fraction; IDA:MGI.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; IDA:MGI.::GO:0017156; P:calcium ion-dependent exocytosis; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
89Q9QY06    2114   MYO9B_MOUSE Unconventional myosin-IXb OS=Mus ...960.00008     49.7     28     50GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
90Q3UIA2    846   RHG17_MOUSE Rho GTPase-activating protein 17 ...870.00009     49.7     33     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
91Q62796    647   RBP1_RAT RalA-binding protein 1 OS=Rattus nor...880.00009     49.3     32     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IMP:RGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007052; P:mitotic spindle organization; IDA:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IPI:RGD.
records
Previous ‹‹ ›› Next Total records: 206 61 - 90
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::