Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR389W
Length:
654
Number of sequences:
5887
Description:
YDR389W SAC7 SGDID:S000002797, Chr IV from 1252537-1254501, Genome Release 64-1-1, Verified ORF, "GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q8K2H3    851   FA13B_MOUSE Protein FAM13B OS=Mus musculus (M...1210.0005     47     30     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
122Q9R0Z9    1092   RHG07_MOUSE Rho GTPase-activating protein 7 O...840.0005     47     31     56GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0005100; F:Rho GTPase activator activity; NAS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0048041; P:focal adhesion assembly; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0003007; P:heart morphogenesis; IMP:MGI.::GO:0021575; P:hindbrain morphogenesis; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
123P55194    601   3BP1_MOUSE SH3 domain-binding protein 1 OS=Mu...701.7     35.4     29     51GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IPI:MGI.
GO:0007165; P:signal transduction; IEA:InterPro.
124Q96QB1    1528   RHG07_HUMAN Rho GTPase-activating protein 7 O...840.0006     47     30     55GO:0005901; C:caveola; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.::GO:0030900; P:forebrain development; ISS:UniProtKB.::GO:0003007; P:heart morphogenesis; ISS:UniProtKB.::GO:0021575; P:hindbrain morphogenesis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0035024; P:negative regulation of Rho protein signal transduction; IMP:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; IDA:UniProtKB.::GO:0001843; P:neural tube closure; ISS:UniProtKB.::GO:0035307; P:positive regulation of protein dephosphorylation; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
125Q8AVG0    862   ABR_XENLA Active breakpoint cluster region-re...860.0007     46.6     29     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
126Q17R89    818   RHG44_HUMAN Rho GTPase-activating protein 44 ...1130.0007     46.6     26     43GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
127Q54SL6    531   GACQ_DICDI Rho GTPase-activating protein gacQ...850.0007     46.2     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
128Q54WY8    611   GACN_DICDI Rho GTPase-activating protein gacN...860.0007     46.2     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
129O43052    1150   RGA1_SCHPO Rho-type GTPase-activating protein...1110.0007     46.6     30     48GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005100; F:Rho GTPase activator activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0030036; P:actin cytoskeleton organization; IMP:PomBase.::GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro.
130Q5SSM3    814   RHG44_MOUSE Rho GTPase-activating protein 44 ...920.0007     46.6     26     47GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
131O43295    1099   SRGP3_HUMAN SLIT-ROBO Rho GTPase-activating p...770.0008     46.6     32     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
132Q6PAJ1    1270   BCR_MOUSE Breakpoint cluster region protein O...1400.0009     46.2     26     45GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0030675; F:Rac GTPase activator activity; IGI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043314; P:negative regulation of neutrophil degranulation; IGI:MGI.::GO:0050885; P:neuromuscular process controlling balance; IGI:MGI.::GO:0050766; P:positive regulation of phagocytosis; IGI:MGI.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.
133P11274    1271   BCR_HUMAN Breakpoint cluster region protein O...1400.001     46.2     26     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
134A4II46    862   ABR_XENTR Active breakpoint cluster region-re...860.001     46.2     29     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
135Q923Q2    1113   STA13_MOUSE StAR-related lipid transfer prote...930.001     46.2     28     55GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
136Q7YQL5    802   OPHN1_PONPY Oligophrenin-1 OS=Pongo pygmaeus ...890.001     45.8     29     53GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
137Q7YQL6    802   OPHN1_PANTR Oligophrenin-1 OS=Pan troglodytes...890.001     45.8     29     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
138O60890    802   OPHN1_HUMAN Oligophrenin-1 OS=Homo sapiens (H...890.001     45.8     29     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:ProtInc.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006930; P:substrate-dependent cell migration, cell extension; TAS:ProtInc.
139Q559A0    1164   GACU_DICDI Rho GTPase-activating protein gacU...1160.001     45.8     28     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
140Q8K031    1019   STAR8_MOUSE StAR-related lipid transfer prote...840.002     45.4     30     54GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
141A8WRJ2    752   RRC1_CAEBR GTPase-activating protein rrc-1 OS...840.002     45.4     30     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; ISS:UniProtKB.
GO:0007165; P:signal transduction; IEA:InterPro.
142Q54BP9    520   GACV_DICDI Rho GTPase-activating protein gacV...810.002     45.1     36     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
143Q20498    759   RRC1_CAEEL GTPase-activating protein rrc-1 OS...840.002     45.1     30     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007165; P:signal transduction; IEA:InterPro.
144Q9CXP4    425   RHG08_MOUSE Rho GTPase-activating protein 8 O...1350.003     44.3     30     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
145Q6ZW31    735   SYDE1_HUMAN Rho GTPase-activating protein SYD...1120.003     44.7     27     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
146Q9P2N2    729   RHG28_HUMAN Rho GTPase-activating protein 28 ...1200.003     44.3     25     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
147Q7Z6B7    1085   SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating p...770.004     44.3     29     51GO:0005829; C:cytosol; TAS:Reactome.
GO:0007411; P:axon guidance; TAS:Reactome.
148Q92502    1023   STAR8_HUMAN StAR-related lipid transfer prote...840.004     44.3     30     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
149Q6P4F7    1023   RHGBA_HUMAN Rho GTPase-activating protein 11A...1230.005     43.9     26     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
150Q9Y3M8    1113   STA13_HUMAN StAR-related lipid transfer prote...840.005     43.9     29     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
151Q8BN58    729   RHG28_MOUSE Rho GTPase-activating protein 28 ...1160.006     43.5     24     47
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
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